scholarly journals Cognitive decline affects diabetic women

2016 ◽  
Vol 17 (4) ◽  
pp. 272-274 ◽  
Author(s):  
Adam Perzyński ◽  
Iwona Chmiel-Perzyńska
Keyword(s):  
Motor Control ◽  
Cognitive Decline ◽  
Cognitive Functioning ◽  
Cognitive Functions ◽  
Verbal Learning ◽  
Apparent Lack ◽  
Auditory Verbal Learning ◽  
Trail Making ◽  
Learning Test ◽  
Underlying Mechanisms

AbstractIntroduction: DM provokes peripheral complications and changes in central nervous system. Central changes in the course of diabetes mellitus (DM) include changes in brain tissue structure, electrophysiological abnormalities but also disturbances in neurotransmission leading to cognitive decline.Aim of the study: The aim of our study was to asses cognitive functioning of patients suffering from DM1 for at least 5 years but without any diagnosed complications.Materials and methods: Cognitive functions were assessed in 59 patients (35 men) with Trail Making Test A (TMT A) and B (TMT B), Maze Test (MT), Stroop Test (SCWT) and Rey Auditory Verbal Learning Test (RAVLT). Mental disorders were excluded with Beck’s Depression Inventory (BT), Mini Mental State Examination (MMSE) and psychiatric examination.Results: We stated that women, compared with men, presented worsening of executive functions, speed and motor control. Cognitive decline depended on number of episodes of at least moderate hypoglycemia and duration of disease. HbA1c below 8% resulted in better memory, speed and motor control. Cognitive decline was more escalated in the patients with atherogenic lipid profile.Conclusions: It seems that even apparent lack of complications is not unambiguous with lack of cognitive decline and women seem to be more susceptible. DM1 affects young individuals, whose cognitive functions are in the course of the development, so it is important to find the underlying mechanisms and the areas of disturbed cognitive functioning and further investigations are needed.

scholarly journals Association of Anxiety Awareness with Risk Factors of Cognitive Decline in MCI

2021 ◽  
Vol 11 (2) ◽  
pp. 135
Author(s):  
Ariela Gigi ◽  
Merav Papirovitz
Keyword(s):  
Cognitive Decline ◽  
State Anxiety ◽  
Verbal Learning ◽  
Memory Loss ◽  
Control Group ◽  
General Tendency ◽  
General Anxiety ◽  
Auditory Verbal Learning ◽  
Skin Conductivity ◽  
Learning Test

Studies demonstrate that anxiety is a risk factor for cognitive decline. However, there are also study findings regarding anxiety incidence among people with mild cognitive impairment (MCI), which mostly examined general anxiety evaluated by subjective questionnaires. This study aimed to compare subjective and objective anxiety (using autonomic measures) and anxiety as a general tendency and anxiety as a reaction to memory examination. Participants were 50 adults aged 59–82 years who were divided into two groups: MCI group and control group, according to their objective cognitive performance in the Rey Auditory Verbal Learning Test. Objective changes in the anxiety response were measured by skin conductivity in all tests and questionnaires. To evaluate subjective anxiety as a reaction to memory loss, a questionnaire on “state-anxiety” was used immediately after completing memory tests. Our main finding was that although both healthy and memory-impaired participants exhibited elevations in physiological arousal during the memory test, only healthy participants reported an enhanced state anxiety (p = 0.025). Our results suggest that people with MCI have impaired awareness of their emotional state.

scholarly journals Longitudinal Cognitive Performance in Individuals at Ultrahigh Risk for Psychosis: A 10-year Follow-up

2018 ◽  
Vol 45 (5) ◽  
pp. 1101-1111 ◽  
Author(s):  
Kelly Allott ◽  
Stephen J Wood ◽  
Hok Pan Yuen ◽  
Alison R Yung ◽  
Barnaby Nelson ◽  
...  
Keyword(s):  
Cognitive Performance ◽  
Verbal Learning ◽  
Period Change ◽  
Digit Symbol ◽  
Cognitive Measures ◽  
Auditory Verbal Learning ◽  
Trail Making ◽  
Learning Test ◽  
Positive Correlations

Abstract It remains unclear whether the onset of psychosis is associated with deterioration in cognitive performance. The aim of this study was to examine the course of cognitive performance in an ultrahigh risk (UHR) cohort, and whether change in cognition is associated with transition to psychosis and change in functioning. Consecutive admissions to Personal Assessment and Crisis Evaluation (PACE) Clinic between May 1994 and July 2000 who had completed a comprehensive cognitive assessment at baseline and follow-up were eligible (N = 80). Follow-up ranged from 7.3 to 13.4 years (M = 10.4 years; SD = 1.5). In the whole sample, significant improvements were observed on the Similarities (P = .03), Information (P < .01), Digit Symbol Coding (P < .01), and Trail Making Test-B (P = .01) tasks, whereas performance on the Rey Auditory Verbal Learning Test (Trials 1–3) declined significantly (P < .01) over the follow-up period. Change in performance on cognitive measures was not significantly associated with transition status. Taking time to transition into account, those who transitioned after 1 year showed significant decline on Digit Symbol Coding, whereas those who did not transition improved on this measure (P = .01; effect size [ES] = 0.85). Small positive correlations were observed between improvements in functioning and improvements in performance on Digit Symbol Coding and Arithmetic (0.24, P = .03 and 0.28, P = .01, respectively). In summary, the onset of psychosis was not associated with deterioration in cognitive ability. However, specific findings suggest that immediate verbal learning and memory, and processing speed may be relevant domains for future risk models and early intervention research in UHR individuals.

scholarly journals The relationship between neuropsychological performance and depression in patients with traumatic brain injury

2016 ◽  
Vol 47 (2) ◽  
pp. 171-183 ◽  
Author(s):  
Noorjehan Joosub ◽  
Nafisa Cassimjee ◽  
Annelies Cramer
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Verbal Learning ◽  
Neuropsychological Performance ◽  
Auditory Verbal Learning Test ◽  
Symptoms Of Depression ◽  
Auditory Verbal Learning ◽  
Trail Making ◽  
Learning Test ◽  
The Relationship

Traumatic brain injury is a multi-faceted condition that affects individuals on physical, cognitive, and emotional levels. The study investigated the relationship between depression and neuropsychological performance in a group with traumatic brain injury. A retrospective review was conducted on 75 participants who completed neuropsychological assessments. Information on clinical characteristics, sociodemographic information, neuropsychological outcomes, and Beck Depression Inventory scores were included in the analysis. Results indicated that 36% of the participants reported experiencing severe symptoms of depression, 28% moderate symptoms of depression, and 36% mild/minimal symptoms of depression. Performance on the Rey Auditory Verbal Learning Test indicated inverse relationships with depression scores suggesting that traumatic brain injury patients with lower depression scores perform better on verbal memory tasks. Similarly, findings for the written and oral versions of the Symbol Digit Modalities Test reflected inverse correlations with depression scores, indicating that lower depression scores are correlated with increased processing speed and capacity. A significant positive association between the time taken to complete the Trail Making Test Trail A and Trail B and depression scores was found, suggesting that higher depression scores in this sample were related to slower performance speed and lower executive performance. When specific clinical and sociodemographic variables were included as covariates in a partial correlational analysis, neuropsychological performance indicators and depression scores remained significant for Symbol Digit Modalities Test (oral and written), the Rey Auditory Verbal Learning Test Retrieval and Recognition trials, and Trail Making Test (Trail B). This study indicates that in a traumatic brain injury cohort, depression levels are significantly associated with specific neuropsychological performance measures. The findings of this study have implications for psychosocial treatment planning after a traumatic brain injury and contribute to our understandings of the inter-relationship between cognition and emotion.

scholarly journals Impaired Recent Verbal Memory in Pornography-Addicted Juvenile Subjects

2019 ◽  
Vol 2019 ◽  
pp. 1-5 ◽  
Author(s):  
Pukovisa Prawiroharjo ◽  
Hainah Ellydar ◽  
Peter Pratama ◽  
Rizki Edmi Edison ◽  
Sitti Evangeline Imelda Suaidy ◽  
...  
Keyword(s):  
Verbal Memory ◽  
Visual Memory ◽  
Verbal Learning ◽  
Auditory Verbal Learning Test ◽  
Complex Figure ◽  
Auditory Verbal Learning ◽  
Pornography Addiction ◽  
Trail Making ◽  
Learning Test ◽  
Figure Test

We aimed to find the differences in memory capabilities between pornography-addicted and nonaddicted juveniles. We enrolled 30 juveniles (12–16 y) consisting of 15 pornography addiction and 15 nonaddiction subjects. We used Rey Auditory Verbal Learning Test (RAVLT) to measure verbal memory, Rey–Osterrieth Complex Figure Test (ROCFT) for visual memory, along with Trail Making Test A and B (TMT-A and TMT-B) for attention. We found a significant reduction in the RAVLT A6 result of the addiction group (nonaddiction vs addiction: 13.47 ± 2.00 vs 11.67 ± 2.44, MD = −1.80, p=0.04), but not in ROCFT or attention tests. Analysis in sex subgroups yielded no sex-specific difference. We concluded that pornography addiction may be associated with impaired recent verbal memory in juveniles, regardless of sex and without association to attention.

Do patients with better neuro-cognition have better theory of mind?

2016 ◽  
Vol 33 (S1) ◽  
pp. S140-S140
Author(s):  
J. Mrizak ◽  
A. Arous ◽  
R. Trabelsi ◽  
A. Aissa ◽  
H. Ben Ammar ◽  
...  
Keyword(s):  
Theory Of Mind ◽  
Cognitive Functioning ◽  
Digit Span ◽  
Verbal Learning ◽  
Card Sorting ◽  
Trail Making ◽  
Competing Interest ◽  
St Number ◽  
Learning Test ◽  
Sorting Test

IntroductionTheory of mind (ToM) has repeatedly been shown to be compromised in many patients with schizophrenia (SCZ). By contrast, the association between ToM deficits and neuro-cognitive functioning (NF) remains uncertain.ObjectivesTo investigate the association between ToM functioning and neuro-cognitive functioning in SCZ.MethodsFifty-eight outpatients with stable SCZ completed the intention-inferencing task (IIT), in which the ability to infer a character's intentions from 28 short comic strip stories is assessed. They also completed a neuro-cognitive battery comprising the following tests: the Hopkins Verbal Learning Test–Revised (HVLT-R), the Letter Digit Substitution Test (LDST), the Stroop Test (ST), the “Double Barrage” of Zazzo (DBZ), the Modified Card Sorting Test (MCST), Verbal Fluency (VF), the Trail Making Test-Part A (TMT-A) and the Digit Span (DS).ResultsThe performance in the IIT significantly correlated with performance in some neuro-cognitive tests including efficiency in DBZ, number of uncorrected mistakes in ST, number of correct categories in MCST and the time needed to succeed the TMT-A. No correlations were found between performance in the ITT and in memory tasks (HVLT-R and DS).ConclusionsToM may rely on some neuro-cognitive functions (mainly attention and executive functioning). Elucidating the exact relationship between ToM and NF may be useful as both are targeted in specific psychotherapeutic interventions.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals The recency ratio as predictor of early MCI

2018 ◽  
Vol 30 (12) ◽  
pp. 1883-1888 ◽  
Author(s):  
Davide Bruno ◽  
Rebecca L. Koscik ◽  
John L. Woodard ◽  
Nunzio Pomara ◽  
Sterling C. Johnson
Keyword(s):  
Cognitive Decline ◽  
Recall Performance ◽  
Verbal Learning ◽  
Consensus Conference ◽  
Older Individuals ◽  
Auditory Verbal Learning Test ◽  
Auditory Verbal Learning ◽  
Binomial Regression ◽  
Learning Test ◽  
Experimental Neuropsychology

ABSTRACTObjectives:Individuals with Alzheimer's disease (AD) present poor immediate primacy recall accompanied by intact or exaggerated recency, which then tends to decline after a delay. Bruno et al. (Journal of Clinical and Experimental Neuropsychology, Vol. 38, 2016, pp. 967–973) have shown that higher ratio scores between immediate and delayed recency (i.e. the recency ratio; Rr) are associated with cognitive decline in high-functioning older individuals. We tested whether Rr predicted conversion to early mild cognitive impairment (early MCI) from a cognitively healthy baseline.Design:Data were analyzed longitudinally with binomial regression. Baseline scores were used to predict conversion to early MCI after approximately nine years. Setting: Data were collected at the Wisconsin Registry of Alzheimer's Prevention, in Madison, Wisconsin.Participants:For the study, 427 individuals were included in the analysis; all participants were 50 years of age or older and cognitively intact at baseline, and were native English speakers.Measurements:Memory data were collected using the Rey's Auditory Verbal Learning Test, and the early MCI diagnosis was obtained via consensus conference.Results:Our results showed that higher Rr scores are correlated with greater risk of later early MCI diagnosis, and this association is independent of total recall performance.Conclusions:Rr is an emerging cognitive marker of cognitive decline.

Statins, Enzyme CoQ10 Supplement Use, and Cognitive Functioning

2021 ◽  
pp. 089198872110447
Author(s):  
Brian G. Collin ◽  
Dheeraj Raju ◽  
Steven Katsikas
Keyword(s):  
Cognitive Functioning ◽  
Test Performance ◽  
Neuropsychological Test ◽  
Verbal Learning ◽  
Prevention Study ◽  
Wechsler Memory Scale ◽  
Supplement Use ◽  
Auditory Verbal Learning ◽  
Medical Histories ◽  
Learning Test

Objective: The current study assessed the effects of statin and CoQ10 supplement use on changes in cognitive functioning in the Wisconsin Registry for Alzheimer’s Prevention study. Methods: 1,573 subjects were administered medical histories, the Mini-Mental State Examination (MMSE), Rey Auditory Verbal Learning Test (RAVLT), Wechsler Memory Scale, Logical Memory subtest, and the Trail Making Test, Parts A (TMT-A) and B (TMT-B) 3-4 times over 5-10 years. Results: Linear mixed models did not yield significant effects for statin or CoQ10 supplement use on changes in mental status, learning and memory, psychomotor speed, and cognitive flexibility. Conclusions: Statin and/or CoQ10 supplement use was not associated with neuropsychological test performance in the Wisconsin Registry for Alzheimer’s Prevention study.

Cognitive functions in tardive dyskinesia

1983 ◽  
Vol 13 (3) ◽  
pp. 671-674 ◽  
Author(s):  
Marion E. Wolf ◽  
Joseph J. Ryan ◽  
Aron D. Mosnaim
Keyword(s):  
Tardive Dyskinesia ◽  
Affective Disorder ◽  
Cognitive Functions ◽  
Psychiatric Patients ◽  
Verbal Learning ◽  
Adult Intelligence Scale ◽  
Auditory Verbal Learning Test ◽  
Wechsler Memory Scale ◽  
Auditory Verbal Learning ◽  
Learning Test

SynopsisCognitive functions of psychiatric patients with and without tardive dyskinesia were evaluated using the Wechsler Adult Intelligence Scale, Wechsler Memory Scale and Rey Auditory Verbal Learning Test. Schizophrenic patients with and without tardive dyskinesia did not differ in their performance on the administered psychological tests. However, affective disorder patients with tardive dyskinesia showed significantly more impairment on the Wechsler Memory Scale and Rey Auditory Verbal Learning Test than affective disorder patients without tardive dyskinesia. These findings suggest that affective disorder patients who develop tardive dyskinesia may have some predisposing brain damage or that tardive dyskinesia in these patients represents both a motor and a dementing disorder.

scholarly journals Known-Groups and Convergent Validity of the Telephone Rey Auditory Verbal Learning Test total Learning Scores for Distinguishing Between Older Adults With Amnestic Cognitive Impairment and Subjective Cognitive Decline

2020 ◽  
Author(s):  
Shreya Jagtap ◽  
Deirdre R Dawson ◽  
Susan Vandermorris ◽  
Nicole D Anderson ◽  
Naomi Davids-Brumer ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Cognitive Decline ◽  
Convergent Validity ◽  
Verbal Learning ◽  
Subjective Cognitive Decline ◽  
Total Recall ◽  
Auditory Verbal Learning Test ◽  
Auditory Verbal Learning ◽  
Learning Test

Abstract Objective To examine known-groups validity of a telephone administration of the total learning scores of the Rey Auditory Verbal Learning Test (RAVLT) in discriminating between people with subjective cognitive decline (SCD) and amnestic mild cognitive impairment (aMCI) and convergent validity of the telephone-RAVLT. Method In total, 83 older adults (age = 71.4 ± 7.0) with SCD or aMCI completed the RAVLT learning trials over the telephone and the Hopkins Verbal Learning Test (HVLT) in-person. Results Telephone-RAVLT total recall significantly correlated with HVLT total recall (r = .49, p &lt; .001). Significant between group differences were found (effect size = 0.94). Conclusions This study provides support for known-groups and convergent validity of the telephone-RAVLT.

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