Kinetics of highly sensitive troponin I and T after eccentric exercise

2010 ◽  
Vol 48 (11) ◽  
Author(s):  
Giuseppe Lippi ◽  
Franco Impellizzeri ◽  
Gian Luca Salvagno ◽  
Monica Mion ◽  
Martina Zaninotto ◽  
...  
Keyword(s):  
Eccentric Exercise ◽  
Troponin I ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Kinetics Of

scholarly journals The Influence of Regular Hemodialysis on the Highly Sensitive Troponin-I Level in Children without Any Symptoms

2021 ◽  
Vol 11 (02) ◽  
pp. 183-198
Author(s):  
Hekmat Mohamed ◽  
Maha Youssef ◽  
Manal Abdel-Salam ◽  
Shayma A. Mohammed
Keyword(s):  
Troponin I ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Regular Hemodialysis

scholarly journals The value of highly sensitive troponin in the early diagnosis of acute myocardial infarction.

2018 ◽  
Vol 96 (1) ◽  
pp. 25-29
Author(s):  
N. N. Borovkov ◽  
Natalya A. Golitsyna
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Early Diagnosis ◽  
Diagnostic Accuracy ◽  
Clinical Significance ◽  
Cardiac Troponin ◽  
Troponin I ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Sensitivity Specificity

Aim. Study the immediate clinical significance of determination of highly sensitive troponin (high sensitive cardiac troponin - hscTn) in the early diagnosis of acute myocardial infarction (AMI). Material and methods. The analysis of nosological diagnosis in 92 patients with acute coronary syndrome (ACS), urgently hospitalized in the coronary care unit of the Nizhny Novgorod regional hospital. N.A. Semashko. The time from the moment of development of pain syndrome, hospitalization in a hospital ranged from 40 minutes to 4 hours, averaging 2.5 ± 0.32 hours. During hospitalization of patients in the complex diagnosis of AMI in addition to General clinical examination, ECG was determined by the content hscTn and troponin I. All patients in the hospital was performed selective coronary angiography (SCG). Evaluated the sensitivity, specificity and diagnostic accuracy hscTn in comparison with troponin I. Analysis results were represented as a percentage and using a software package "STATISTICA 10.0" (StatSoft, Inc., USA). Results. AMI is diagnosed in 74% of cases (n=68), and the rest 26% (n=24) unstable (progressive) angina (NS). Transmural myocardial infarction or Q-wave myocardial infarction detected in 54% (n=37) of patients. Intramural myocardial infarction or non Q-wave myocardial infarction - in 46% (n=31). AMI re-seen in 27% (n=18). Importance of the study of both cardiac troponin in the early diagnosis of AMI showed the following. Sensitivity hscTn reached 98%, while troponin I - 88%. Specificity hscTn was 79%, and troponin I, only 66%. Overall diagnostic accuracy hscTn was 92%, troponin I less - 83%). Conclusion. The results of the study indicate a predominant clinical significance hscTn in comparison with troponin I in early diagnosis of AMI in the parameters of sensitivity, specificity and diagnostic accuracy.

scholarly journals COMPARISON OF HIGHLY SENSITIVE TROPONIN I AND T RESULTS IN THE DIAGNOSIS OF ACUTE MYOCARDIAL INFARCTION

2013 ◽  
Vol 61 (10) ◽  
pp. E228 ◽  
Author(s):  
William Parsonage ◽  
Louise Cullen ◽  
Jaimi Greenslade ◽  
Jill Tate ◽  
Jacobus Ungerer ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Troponin I ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

scholarly journals Highly Sensitive Troponin Assays and the Cardiology Community: A Love/Hate Relationship?

2011 ◽  
Vol 57 (6) ◽  
pp. 826-829 ◽  
Author(s):  
James A de Lemos ◽  
David A Morrow ◽  
Christopher R deFilippi
Keyword(s):  
Cardiac Troponin ◽  
Cardiovascular Health ◽  
Troponin I ◽  
Troponin T ◽  
Cardiac Injury ◽  
Improve Patient Care ◽  
Fourth Generation ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
Improve Patient

Abstract The development of highly sensitive assays for cardiac troponin T (hs-cTnT)4 and cardiac troponin I (hs-cTnI) represents the latest technological advance in a field that has witnessed continual progression toward more sensitive and more precise tools for detecting cardiac injury. The hs-cTnT assay, for example, can detect cTnT concentrations 10-fold lower than the current fourth-generation assay, with high precision at the myocardial infarction (MI) detection limit. Despite the potential for such evolution to improve patient care, clinicians, including practicing cardiologists, often find themselves poorly prepared for the introduction of more-sensitive assays, because they fail to consider the implications of increasing sensitivity on the interpretation of the test results. We believe that highly sensitive troponin assays offer new opportunities to improve cardiovascular health, but they also present challenges in the areas in which troponin testing is most commonly used today.

Comparison of conventional and highly-sensitive troponin I measurement in ultra-marathon runners

2011 ◽  
Vol 33 (4) ◽  
pp. 338-342 ◽  
Author(s):  
Giuseppe Lippi ◽  
Federico Schena ◽  
Gian Luca Salvagno ◽  
Cantor Tarperi ◽  
Rosalia Aloe ◽  
...  
Keyword(s):  
Troponin I ◽  
Marathon Runners ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin

scholarly journals THE SIGNIFICANCE OF HIGH-SENSITIVE TROPONIN I UNDER VARIOUS FORMS OF INFECTIOUS ENDOCARDITIS

2017 ◽  
Vol 23 (4) ◽  
pp. 175-181
Author(s):  
T. A Fedorova ◽  
Serafima Ya. Tazina ◽  
A. N Gerasimov ◽  
N. A Semenenko
Keyword(s):  
Troponin I ◽  
Clinical Laboratory ◽  
Pathological Process ◽  
Functional Class ◽  
Cardiac Insufficiency ◽  
Infectious Endocarditis ◽  
Highly Sensitive ◽  
Highly Sensitive Troponin ◽  
The Relationship ◽  
High Sensitive Troponin

The study was carried out to analyze dynamics of highly sensitive Troponin I in patients with infectious endocarditis with the purpose of specifying its role in evaluation of myocardium condition and prognosis of disease. The sampling included 241 patients being on treatment in the S.P. Botkin municipal clinical hospital. The article presents characteristics of disease at actual stage, clinical laboratory and instrumental comparisons permitted to establish features and patterns of alterations of hsTnI in patients with primary and secondary infectious endocarditis. The relationship is established between increasing of indicator and clinical expression of infectious toxic syndrome, presence of complications, multi-functional alterations of myocardium and functional class of cardiac insufficiency. It is demonstrated that absence of positive dynamics of marker against the background of therapy is a unfavorable prognostic indication and increases a risk of lethal outcome.The obtained results testify undeniable involvement of cardiac muscle into development of pathological process under infectious endocarditis that alongside with valvular pathology determines severity of cardiac insufficiency and prognosis of disease.

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