Measures for reducing ultra-high-molecular-weight polyethylene wear in total knee replacement: a simulator study / Reduzierter UHMWPE-Abrieb im Rahmen der Knieendoprothetik: eine Simulatorstudie

2007 ◽  
Vol 52 (4) ◽  
pp. 295-300 ◽  
Author(s):  
Ralf Mueller-Rath ◽  
Bernhard Kleffner ◽  
Stefan Andereya ◽  
Torsten Mumme ◽  
Dieter Christian Wirtz
Author(s):  
Katherine Etter ◽  
Abhishek S Chitnis ◽  
Chantal E Holy ◽  
F Scott Gray ◽  
Fernando J Manalac ◽  
...  

Aim: To examine the time-to-total knee replacement (TKR) surgery among patients with high-concentration nonavian high-molecular-weight hyaluronan injection (HMW-HA) compared with those without HA injections. Materials & methods: Using MarketScan® Commercial claims all patients aged 18–64 who underwent TKR surgery between 2008 and 2017 were identified. Time-to-TKR surgery was compared between patients receiving Orthovisc® (Anika Therapeutics Inc. Bedford MA, USA, referred to as nonavian HMW-HA) injections and patients who did not receive an HA injection. Results: The median time-to-TKR surgery was 893 days in the nonavian HMW-HA cohort and 399 days in the non-HA cohort (p < 0.001), a difference of 494 days (16.2 months). Conclusion: This study demonstrates that the time-to-TKR surgery is 16.2 months longer in patients who received treatment with nonavian HMW-HA injections.


Author(s):  
John Goodfellow ◽  
John O'Connor ◽  
Hemant Pandit ◽  
Christopher Dodd ◽  
David Murray

Having demonstrated in Chapter 2 that a fully conforming mobile bearing can minimise polyethylene wear, in this chapter we show that a mobile bearing prosthesis, unconstrained in the sagittal plane, can restore natural mobility and stability. For surgeon readers who are less interested in the theoretical background, it might be advisable to go straight to Chapter 4, Indications, or to start by reading the final section of this chapter, The Loaded Prosthetic Knee. If that proves interesting, the surgeon might attempt The Unloaded Prosthetic Knee. For the more research minded surgeon or engineer, it seems more logical to start with the Unloaded Natural Knee (the longest section of the chapter) and to read from there. The chapter may also be of interest to those surgeons embarking on the use of a bi-cruciate retaining total knee replacement.


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