Histomorphometrische Evaluation poröser Titanprobenkörper anhand eines computergestützten Bildanalysesystems / Histomorphometric evaluation of bone ingrowth of porous titanium by a computer-assisted analyzing system

2005 ◽  
Vol 50 (12) ◽  
pp. 408-412 ◽  
Author(s):  
S Endres ◽  
M Wilke ◽  
H Frank ◽  
P Knöll ◽  
M Kratz ◽  
...  
Keyword(s):  
Bone Ingrowth ◽  
Porous Titanium ◽  
Computer Assisted

scholarly journals Enhancement of Bone Ingrowth into a Porous Titanium Structure to Improve Osseointegration of Dental Implants: A Pilot Study in the Canine Model

Materials ◽  
2020 ◽  
Vol 13 (14) ◽  
pp. 3061 ◽  
Author(s):  
Ji-Youn Hong ◽  
Seok-Yeong Ko ◽  
Wonsik Lee ◽  
Yun-Young Chang ◽  
Su-Hwan Kim ◽  
...  
Keyword(s):  
Porous Structure ◽  
Dental Implants ◽  
Bone Growth ◽  
Bone Ingrowth ◽  
Test Group ◽  
Porous Titanium ◽  
Control Group ◽  
Machined Surface ◽  
Significant Difference ◽  
Titanium Structure

A porous titanium structure was suggested to improve implant stability in the early healing period or in poor bone quality. This study investigated the effect of a porous structure on the osseointegration of dental implants. A total of 28 implants (14 implants in each group) were placed in the posterior mandibles of four beagle dogs at 3 months after extraction. The control group included machined surface implants with an external implant–abutment connection, whereas test group implants had a porous titanium structure added to the apical portion. Resonance frequency analysis (RFA); removal torque values (RTV); and surface topographic and histometric parameters including bone-to-implant contact length and ratio, inter-thread bone area and ratio in total, and the coronal and apical parts of the implants were measured after 4 weeks of healing. RTV showed a significant difference between the groups after 4 weeks of healing (p = 0.032), whereas no difference was observed in RFA. In the test group, surface topography showed bone tissue integrated into the porous structures. In the apical part of the test group, all the histometric parameters exhibited significant increases compared to the control group. Within the limitations of this study, enhanced bone growth into the porous structure was achieved, which consequently improved osseointegration of the implant.

Long-Term Study of Osteoconductivity of Bioactive Porous Titanium Metals: Effect of Sodium Removal by Dilute HCl Treatment

2008 ◽  
Vol 396-398 ◽  
pp. 353-356 ◽  
Author(s):  
Kojiro Tanaka ◽  
Mitsuru Takemoto ◽  
Shunsuke Fujibayashi ◽  
Keiichi Kawanabe ◽  
Tomiharu Matsushita ◽  
...  
Keyword(s):  
Heat Treatment ◽  
Bone Ingrowth ◽  
Titanium Implant ◽  
Sodium Titanate ◽  
Porous Titanium ◽  
Hot Water ◽  
Sodium Removal ◽  
Long Term Study ◽  
Free Treatment

In a previous study, we have reported that sodium removal by dilute hydrochloric acid (HCl) converted the sodium titanate layer on the surface of an alkali-treated porous titanium into titania with a specific structure that has better bioactivity than sodium titanate. We have shown that a porous titanium with this treatment have good osteoinductivity in soft tissue of canines. In the present study, we investigated the effect of this treatment on the osteoconductive abilities of porous bioactive titanium implant in the long term. Three types of surface treatments were applied: (a) no treatment , (b) alkali, hot water, and heat treatment ( conventional treatment: W-AH treatment), and (c) alkali, dilute HCl, hot water, and heat treatment (Na-free treatment: HCl-AH treatment). We then examined the osteoconductivity of the materials implanted in the femoral condyles of Japanese white rabbits at 6, 12, 26, and 52 weeks. The results showed that the bone ingrowth in HCl-AH porous bioactive titanium was significantly higher than in W-AH porous bioactive titanium at 52 weeks. Therefore, sodium removal has a positive effect on the osteoconductivity of the porous bioactive titanium implant in the long term.

Novel Micro-CT Based 3-Dimentional Structural Analyses of Porous Biomaterials

2007 ◽  
Vol 330-332 ◽  
pp. 967-970 ◽  
Author(s):  
B. Otsuki ◽  
Mitsuru Takemoto ◽  
Shunsuke Fujibayashi ◽  
Masashi Neo ◽  
Tadashi Kokubo ◽  
...  
Keyword(s):  
Network Structure ◽  
Bone Ingrowth ◽  
Average Pore Size ◽  
Three Dimensional ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Average Pore ◽  
Tissue Ingrowth ◽  
Porous Biomaterials

A porous structure comprises pores and pore throats with a complex three-dimensional network structure, and many investigators have described the relationship between average pore size and the amount of bone ingrowth. However, the influence of network structure or pore throats for tissue ingrowth has rarely been discussed. Bioactive porous titanium implants with 48% porosity were analyzed using specific algorithms for three-dimensional analysis of interconnectivity based on a micro focus X-ray computed tomography system. In vivo histological analysis was performed using the very same implants implanted into the femoral condyles of male rabbits for 6 weeks. This matching study revealed that more poorly differentiated pores tended to have narrow pore throats, especially in their shorter routes to the outside. Data obtained suggest that this sort of novel analysis is useful for evaluating bone and tissue ingrowth into porous biomaterials.

Bone Ingrowth Into Porous Bioactive Titanium Implant for Load-Bearing Use: Experimental Study Using a Novel Canine Anterior Interbody Fusion Model

2007 ◽  
Vol 330-332 ◽  
pp. 987-990
Author(s):  
Mitsuru Takemoto ◽  
Shunsuke Fujibayashi ◽  
Masashi Neo ◽  
Kazutaka So ◽  
Norihiro Akiyama ◽  
...  
Keyword(s):  
Interbody Fusion ◽  
Bone Ingrowth ◽  
Average Pore Size ◽  
Fibrous Tissue ◽  
Titanium Implant ◽  
Porous Titanium ◽  
Histological Evaluation ◽  
Biological Fixation ◽  
Load Bearing ◽  
Porous Titania

We have developed a porous titanium implant sintered with spacer particles (porosity = 50 %, average pore size ± standard deviation = 303 ± 152 !m, yield compression strength = 100MPa). This porous titanium was successfully treated with chemical and thermal treatment that gives a bioactive micro-porous titania layer on the titanium surface, and it is expected as effective biomaterial for biological fixation on load bearing condition. In this study, ten adult female beagle dogs underwent anterior lumbar interbody fusion at L6-7 using either BT-implant or non-treated implant (NT-implant), then followed by posterior interspinous wiring and facet screw fixation. The radiographic evaluations were performed 1, 2 and 3 months postoperatively using X-ray fluoroscopy. Animals were sacrificed after 3 months postoperatively, and fusion status was evaluated by manual palpation. Histological evaluation was also performed. Both histological and radiological evaluation revealed that interbody fusion was achieved in 5 of 5 dogs (100%) in BT-group and 3 of 5 dogs (60%) in NT-group. In BT implants, we could observe a large amount of new bone formation from periphery to the center of the implant, whereas in NT implants, fibrous tissue formation was still observed even in the implants with successful fusion. The results of this study indicate that porous bioactive titanium implant will represent a new osteoconductive biomaterial with improved fusion characteristics.

Fabrication of bioactive 3D printed porous titanium implants with Sr ion-incorporated zeolite coatings for bone ingrowth

2018 ◽  
Vol 6 (20) ◽  
pp. 3254-3261 ◽  
Author(s):  
Shuang Wang ◽  
Ruiyan Li ◽  
Dongdong Li ◽  
Zhi-Yong Zhang ◽  
Guancong Liu ◽  
...  
Keyword(s):  
Bone Ingrowth ◽  
Porous Titanium ◽  
Titanium Implants ◽  
3D Printed ◽  
Strontium Ion ◽  
Zeolite Coatings

Strontium ion incorporated zeolites are uniformly fabricated on a 3D printed porous titanium scaffold for bone ingrowth.

scholarly journals Initial evaluation of bone ingrowth into a novel porous titanium coating

2010 ◽  
Vol 9999B ◽  
pp. NA-NA ◽  
Author(s):  
Rima M. Wazen ◽  
Louis-Philippe Lefebvre ◽  
Eric Baril ◽  
Antonio Nanci
Keyword(s):  
Bone Ingrowth ◽  
Porous Titanium ◽  
Initial Evaluation ◽  
Titanium Coating

scholarly journals Bone Ingrowth Through Porous Titanium Granulate Around a Femoral Stem

2007 ◽  
Vol 112 (2) ◽  
pp. 191-197 ◽  
Author(s):  
Thomas M Turner ◽  
Robert M. Urban ◽  
Deborah J. Hall ◽  
Gunnar B. J. Andersson
Keyword(s):  
Bone Ingrowth ◽  
Femoral Stem ◽  
Porous Titanium

Fabrication and Compressive Properties of Porous Ti6Al4V Alloy with Elongated Pores for Biomedical Application

2015 ◽  
Vol 815 ◽  
pp. 354-358
Author(s):  
Fu Ping Li ◽  
Jin Shan Li ◽  
Ge Jun Liu ◽  
Hong Chao Kou ◽  
Guang Sheng Xu ◽  
...  
Keyword(s):  
Titanium Alloy ◽  
Biomedical Application ◽  
Bone Ingrowth ◽  
Porous Titanium ◽  
Ti6al4v Alloy ◽  
Anisotropic Structure ◽  
Compressive Properties ◽  
Out Of Plane ◽  
Plane Direction ◽  
Mechanical Compatibility

Porous Ti6Al4V alloys with anisotropic structure for biomedical application was fabricated by diffusion bonding of titanium alloy meshes. Compressive mechanical compatibility of the alloys is investigated as human bone implants. It is concluded that the fabrication processing for porous Ti6Al4V alloys has better control of the porosity. The pore structure of porous titanium is anisotropic, with elongated and square pores in the out-of-plane and in-plane direction, respectively, which is suited for bone ingrowth. The compressive Young’s modulus and yield stress of porous Ti6Al4V alloy compressed in the out-of-plane direction are 12.2 GPa and 171.4 MPa, respectively, which is compatible with those for the cortical bones.

scholarly journals Hydromechanical mechanism behind the effect of pore size of porous titanium scaffolds on osteoblast response and bone ingrowth

2019 ◽  
Vol 183 ◽  
pp. 108151 ◽  
Author(s):  
Pengrong Ouyang ◽  
Hui Dong ◽  
Xijing He ◽  
Xuan Cai ◽  
Yibin Wang ◽  
...  
Keyword(s):  
Pore Size ◽  
Bone Ingrowth ◽  
Porous Titanium

scholarly journals Heat treatment effect on the mechanical properties, roughness and bone ingrowth capacity of 3D printing porous titanium alloy

RSC Advances ◽  
2018 ◽  
Vol 8 (22) ◽  
pp. 12471-12483 ◽  
Author(s):  
Zuhao Li ◽  
Chang Liu ◽  
Bingfeng Wang ◽  
Chenyu Wang ◽  
Zhonghan Wang ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Heat Treatment ◽  
Titanium Alloy ◽  
3D Printing ◽  
Mechanical Strength ◽  
Clinical Application ◽  
Treatment Effect ◽  
Bone Ingrowth ◽  
Porous Titanium

The weak mechanical strength and biological inertia of Ti–6Al–4V porous titanium alloy limit its clinical application in the field of orthopedics.

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