Model-based glycaemic control: methodology and initial results from neonatal intensive care

2017 ◽  
Vol 62 (2) ◽  
Author(s):  
Jennifer L. Dickson ◽  
J. Geoffrey Chase ◽  
Adrienne Lynn ◽  
Geoffrey M. Shaw
Keyword(s):  
Insulin Sensitivity ◽  
Premature Infants ◽  
Retrospective Cohort ◽  
Neonatal Intensive Care ◽  
Good Control ◽  
Model Based ◽  
And Performance ◽  
Control Methodology ◽  
Initial Results ◽  
Over Time

AbstractVery/extremely premature infants often experience glycaemic dysregulation, resulting in abnormally elevated (hyperglycaemia) or low (hypoglycaemia) blood glucose (BG) concentrations, due to prematurity, stress, and illness. STAR-GRYPHON is a computerised protocol that utilises a model-based insulin sensitivity parameter to directly tailor therapy for individual patients and their changing conditions, unlike other common insulin protocols in this cohort. From January 2013 to January 2015, 13 patients totalling 16 hyperglycaemic control episodes received insulin under STAR-GRYPHON. A significant improvement in control was achieved in comparison to a retrospective cohort, with a 26% absolute improvement in BG within the targeted range and no hypoglycaemia. This improvement was obtained predominantly due to the reduction of hyperglycaemia (%BG>10.0 mmol/l: 5.6 vs. 17.7%, p<0.001), and lowering of the median per-patient BG [6.9 (6.1–7.9) vs. 7.8 (6.6–9.1) mmol/l, p<0.001, Mann-Witney U test]. While cohort-wide control results show good control overall, there is high intra-patient variability in BG behaviour, resulting in overly conservative treatments for some patients. Patient insulin sensitivity differs between and within patients over time, with some patients having stable insulin sensitivity, while others change rapidly. These results demonstrate the trade-off between safety and performance in a highly variable and fragile cohort.

scholarly journals Reconciling Authenticity and Reenactment

2022 ◽  
pp. 183-192
Author(s):  
Amy Brost
Keyword(s):  
Theoretical Model ◽  
Community Participation ◽  
Theoretical Models ◽  
Performance Model ◽  
Unique Challenge ◽  
Model Based ◽  
Art Objects ◽  
And Performance ◽  
Ritual Context ◽  
Over Time

Locating authenticity in artworks that are remade (all or in part) or re-performed over time presents a unique challenge for art conservators, whose activities have traditionally been oriented toward caring for the material aspects of art objects. The paper offers a brief overview of perspectives on authenticity and discusses various theoretical models that have been developed to conceptualize how media, installation, and performance artworks are displayed and cared for over time. These include the score/performance model, the concepts of autographicity and allographicity, the concept of iteration, and authenticity as a practice. The author proposes a theoretical model based on the ritual aspects of presenting artworks, arguing that authenticity, repetition, and community participation can be reconciled within a ritual context.

scholarly journals Automatic Vibrotactile Device for Interruption of Apnea in Premature Infants

2010 ◽  
Vol 4 (2) ◽  
Author(s):  
Mojgan Payombar ◽  
Fernando Vera ◽  
Panadda Marayong
Keyword(s):  
Premature Infants ◽  
Neonatal Intensive Care ◽  
Haptic Feedback ◽  
Simulated Data ◽  
Medical Problem ◽  
Patient Treatment ◽  
Preliminary Evaluation ◽  
Blood Oxygen Level ◽  
Control Interface ◽  
And Performance

Apnea in premature infants is a common medical problem faced daily by neonatal intensive-care unit staff worldwide. The condition is defined as a pause in breathing that lasts for 20 s or longer and is traditionally treated by manual simulation administered by a nurse. This work proposes a design of an automatic apnea interruption system for infants, which utilizes a noninvasive vibrotactile (vibration feedback) unit to replace the traditional manual stimulation. The overall system consists of a vibrotactile unit and a device/user control interface that are used with a commercial patient monitoring device. The system monitors physiological signals associated with apnea, such as heart rate and blood oxygen level, and activates the vibrotactile unit in a closed-loop fashion. The system provides multimode haptic feedback for individualized patient treatment by allowing the care provider to adjust the magnitude and duration of the tactile stimulation from the user interface. As a preliminary evaluation, the system is tested for safety and performance using simulated data.

Model-Based Prediction Control for Photovoltaic/Thermal-Assisted Heat Pump Water Heating System

2014 ◽  
Vol 1030-1032 ◽  
pp. 549-552 ◽  
Author(s):  
Huan Liang Tsai ◽  
Li Wen Lai
Keyword(s):  
Heat Pump ◽  
Model Building ◽  
Weather Conditions ◽  
Heating System ◽  
Water Heating ◽  
Climate Conditions ◽  
Model Based ◽  
And Performance ◽  
Prediction Control ◽  
Control Methodology

This paper presents self-sufficiency design for a photovoltaic/thermal assisted heat pump water heating (PVTA/HPWH) system by model-based prediction control methodology. Considering the effect of weather conditions on PVT characteristics, the reciprocal energy exchange of PVT evaporator and HPWH system could be well described by the proposed PVTA/HPWH model with better precision. Having the accurate model building, the power consumption of HPWH is self-sufficiently provided by PV electricity using a model-based prediction control methodology. Performance is evaluated through experimental measurement with a test rig of integrated PVTA/HPWH system of rated power 1 kWp under real climate conditions. The dynamic behaviors and performance analysis of the PVTA/HPWH system are conducted by theoretical and experimental analysis. The results have demonstrated the power autarky of the proposed PVTA/HPWH system with better performance.

Are perceptual disorder signs in diplegic cerebral palsied children stable over time? A retrospective cohort analysis

2020 ◽  
Vol 72 (2) ◽  
Author(s):  
Silvia Alboresi ◽  
Alice Sghedoni ◽  
Giulia Borelli ◽  
Stefania Costi ◽  
Laura Beccani ◽  
...  
Keyword(s):  
Retrospective Cohort ◽  
Cohort Analysis ◽  
Retrospective Cohort Analysis ◽  
Over Time

STUDI FENOMENOLOGI: DUKUNGAN PADA IBU DALAM PERAWATAN BAYI PREMATUR DI RUANG RAWAT INTENSIF NEONATUS

2019 ◽  
Vol 7 (3) ◽  
pp. 198-205
Author(s):  
Anafrin Yugistyowati
Keyword(s):  
Intensive Care ◽  
Premature Infants ◽  
Neonatal Intensive Care ◽  
Discharge Planning ◽  
Premature Baby ◽  
Field Note ◽  
Analyse Data ◽  
Using Data ◽  
Care Ward ◽  
Intensive Care Ward

Background: The premature birth of infants is a process that leads to physical unpreparedness, sources of stress, and traumatize effects for the parents. Mostly mothers showed unpleasant memories that interfered the parents’ ability to take care of their premature baby. Objective: This study aimed  to obtain in-depth understanding of mother’s support in neonatal  intensive care ward. Methods: This is a qualitative research using phenomenology approach involving eight participants. Data were collected through in-depth interview using data recording, interview protocol, and field note. Colaizzi method was used to analyse data. Results: Two research themes were gained from data analysis, the source and the type of support for mother with premature infants’ care. Conclusion: This study recommends for nurses to assist parents by discussing any problems and to facilitate bonding mother and baby through implementation continuum of discharge planning.   Keywords: Care for Premature Infants, Neonatal Intensive Care Ward, Supporting Mothers

scholarly journals An Investigation of the Physical and Electrical Properties of Knitted Electrodes When Subjected to Multi-Axial Compression and Abrasion

Proceedings ◽  
2021 ◽  
Vol 68 (1) ◽  
pp. 2
Author(s):  
Arash M. Shahidi ◽  
Theodore Hughes-Riley ◽  
Carlos Oliveira ◽  
Tilak Dias
Keyword(s):  
Heart Rate ◽  
Electrical Properties ◽  
Applied Load ◽  
Pressure Sensors ◽  
Electrical Performance ◽  
Electronic Textiles ◽  
Heart Rate Monitors ◽  
Mechanical Loads ◽  
And Performance ◽  
Over Time

Knitted electrodes are a key component to many electronic textiles including sensing devices, such as pressure sensors and heart rate monitors; therefore, it is essential to assess the electrical performance of these knitted electrodes under different mechanical loads to understand their performance during use. The electrical properties of the electrodes could change while deforming, due to an applied load, which could occur in the uniaxial direction (while stretched) or multiaxial direction (while compressed). The properties and performance of the electrodes could also change over time when rubbed against another surface due to the frictional force and generated heat. This work investigates the behavior of a knitted electrode under different loading conditions and after multiple abrasion cycles.

scholarly journals A Model-Based Approach for Adaptable Middleware Evolution in WSN Platforms

2021 ◽  
Vol 10 (1) ◽  
pp. 20
Author(s):  
Walter Tiberti ◽  
Dajana Cassioli ◽  
Antinisca Di Marco ◽  
Luigi Pomante ◽  
Marco Santic
Keyword(s):  
Wireless Sensor Networks ◽  
Sensor Networks ◽  
Embedded System ◽  
Operating Systems ◽  
Parallel Evolution ◽  
Wireless Sensor ◽  
New Techniques ◽  
Model Based ◽  
And Performance ◽  
Hardware Platforms

Advances in technology call for a parallel evolution in the software. New techniques are needed to support this dynamism, to track and guide its evolution process. This applies especially in the field of embedded systems, and certainly in Wireless Sensor Networks (WSNs), where hardware platforms and software environments change very quickly. Commonly, operating systems play a key role in the development process of any application. The most used operating system in WSNs is TinyOS, currently at its TinyOS 2.1.2 version. The evolution from TinyOS 1.x and TinyOS 2.x made the applications developed on TinyOS 1.x obsolete. In other words, these applications are not compatible out-of-the-box with TinyOS 2.x and require a porting action. In this paper, we discuss on the porting of embedded system (i.e., Wireless Sensor Networks) applications in response to operating systems’ evolution. In particular, using a model-based approach, we report the porting we did of Agilla, a Mobile-Agent Middleware (MAMW) for WSNs, on TinyOS 2.x, which we refer to as Agilla 2. We also provide a comparative analysis about the characteristics of Agilla 2 versus Agilla. The proposed Agilla 2 is compatible with TinyOS 2.x, has full capabilities and provides new features, as shown by the maintainability and performance measurement presented in this paper. An additional valuable result is the architectural modeling of Agilla and Agilla 2, missing before, which extends its documentation and improves its maintainability.

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