scholarly journals Increased responsiveness to synthetic thyrotropin-releasing hormone (TRH) in androgenized adult rats with special reference to the dose of testosterone propionate for androgenization.

1979 ◽  
Vol 26 (4) ◽  
pp. 459-464
Author(s):  
TOMOKO FUJII ◽  
JUNZO KATO ◽  
KATSUMI WAKABAYASHI
Endocrinology ◽  
1984 ◽  
Vol 114 (4) ◽  
pp. 1334-1337 ◽  
Author(s):  
BRYAN WOLF ◽  
SONIA ARATAN-SPIRE ◽  
PAUL CZERNICHOW

1973 ◽  
Vol 62 (12) ◽  
pp. 1655-1662
Author(s):  
Masahiro SAKODA ◽  
Makoto OHTSUKT ◽  
Hidetaro MORI ◽  
Makoto TATEIWA ◽  
Takaaki KUSAKA ◽  
...  

Neuroreport ◽  
1999 ◽  
Vol 10 (17) ◽  
pp. 3501-3505 ◽  
Author(s):  
Cesario V. Borlongan ◽  
Christine E. Stahl ◽  
Eva Redei ◽  
Yun Wang

1979 ◽  
Vol 57 (1) ◽  
pp. 31-34 ◽  
Author(s):  
P. Walker ◽  
J. H. Dussault

Fetal and neonatal rats received daily subcutaneous injections of 10 μg thyrotropin-releasing hormone (TRH) until 7 or 14 days postnatally. At 70 days the pups were challenged with 1 μg TRH intravenously via an indwelling jugular cannula. Basal serum thyroxine, triiodothyronine, and thyroid-stimulating hormone (TSH) concentrations did not differ among the three groups. The mean TSH responses as determined by the mean peak TSH concentration and the total TSH response as determined by planimetry were not significantly different, and there was no significant difference in pituitary TSH content following the TRH challenge among the three groups. This study suggests that the integrity of the hypothalamo–pituitary axis in adult rats cannot be affected by the repeated administration of pharmacologic doses of TRH during the perinatal period.


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