scholarly journals Oral DDAVP is a Good Alternative Therapy for Patients with Central Diabetes Insipidus: Experience of Five-Year Treatment

2003 ◽  
Vol 50 (4) ◽  
pp. 437-443 ◽  
Author(s):  
Izumi FUKUDA ◽  
Naomi HIZUKA ◽  
Kazue TAKANO
2018 ◽  
Vol 8 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Basmah Abdallah ◽  
Spencer Hodgins ◽  
Daniel Landry ◽  
Michael O’Shea ◽  
Gregory Braden

Oxcarbazepine and carbamazepine cause hyponatremia by unknown mechanisms. We describe a patient with complete central diabetes insipidus and seizures who developed worsening hyponatremia when her dose of oxcarbazepine was increased. The patient maintained a normal serum sodium level and has had appropriately concentrated urine for 5 years on just oxcarbazepine, despite undetectable antidiuretic hormone (ADH) levels. This suggests that oxcarbazepine (or one of its metabolites) may stimulate collecting tubule V2 receptor-G protein complex independent of ADH, resulting in increased renal tubular water reabsorption. Oxcarbazepine may be useful as an alternative therapy for patients with central diabetes insipidus.


2018 ◽  
Author(s):  
Ana Ferreira ◽  
Tiago Silva ◽  
Filipa Bastos ◽  
Isabel Manita ◽  
Maria Carlos Cordeiro ◽  
...  

2019 ◽  
Author(s):  
Najoua Lassoued ◽  
Salmane Wannes ◽  
Asma Wardani ◽  
Abir Omrane ◽  
Raoudha Boussofara ◽  
...  

2019 ◽  
Author(s):  
Benedict Morin ◽  
Bettina Winzeler ◽  
Julie Refardt ◽  
Cornelia Imber ◽  
Wiebke Fenske ◽  
...  

2018 ◽  
Vol 44 (1) ◽  
Author(s):  
Ayako Ito ◽  
Aya Nozaki ◽  
Ichiro Horie ◽  
Takao Ando ◽  
Atsushi Kawakami

2021 ◽  
Vol 9 (8) ◽  
Author(s):  
Karin Imaizumi ◽  
Shun Yasuda ◽  
Naoya Toba ◽  
Takayuki Okazaki ◽  
Toma Fukuda ◽  
...  

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