The role of Italian incubators and Science Parks in the Triple-Helix era. The hybrid model developed in Lombardy

2011 ◽  
Vol 2 (3/4) ◽  
pp. 290 ◽  
Author(s):  
Cinzia Colapinto
Author(s):  
Francesco Lamperti ◽  
Roberto Mavilia ◽  
Simona Castellini
Keyword(s):  

2021 ◽  
Vol 22 (5) ◽  
pp. 2426
Author(s):  
Askhat Myngbay ◽  
Limara Manarbek ◽  
Steve Ludbrook ◽  
Jeannette Kunz

Rheumatoid arthritis (RA) is a chronic autoimmune disease causing inflammation of joints, cartilage destruction and bone erosion. Biomarkers and new drug targets are actively sought and progressed to improve available options for patient treatment. The Collagen Triple Helix Repeat Containing 1 protein (CTHRC1) may have an important role as a biomarker for rheumatoid arthritis, as CTHRC1 protein concentration is significantly elevated in the peripheral blood of rheumatoid arthritis patients compared to osteoarthritis (OA) patients and healthy individuals. CTHRC1 is a secreted glycoprotein that promotes cell migration and has been implicated in arterial tissue-repair processes. Furthermore, high CTHRC1 expression is observed in many types of cancer and is associated with cancer metastasis to the bone and poor patient prognosis. However, the function of CTHRC1 in RA is still largely undefined. The aim of this review is to summarize recent findings on the role of CTHRC1 as a potential biomarker and pathogenic driver of RA progression. We will discuss emerging evidence linking CTHRC1 to the pathogenic behavior of fibroblast-like synoviocytes and to cartilage and bone erosion through modulation of the balance between bone resorption and repair.


Biochemistry ◽  
2003 ◽  
Vol 42 (14) ◽  
pp. 4042-4048 ◽  
Author(s):  
James G. Bann ◽  
Hans Peter Bächinger ◽  
David H. Peyton

ARGOMENTI ◽  
2009 ◽  
pp. 99-122
Author(s):  
Alessandro Minello

- Cluster policy today represent one of the main elements of the European agenda, both for policy makers and for practitioners. In the last decade an extensive-type cluster policy has produced a proliferation of clusters all over the Europe, but the generated quality of clusters created has not always been quite satisfactory. Following the input by the European commission, currently is underway a qualitative review of the goals and processes of European cluster policy. This paper aims at presenting such changes in the European cluster policy, beside the main lessons that can be learned. The analysis emphasizes some critical elements of the current process of "clustering" and highlights the role of the institutions, besides the market, in the planning of new clusters and the strengthening of those existing. The final message is that Europe needs a better cluster policy, rather than more clusters, according to the growing complexity and dynamism of clusters.Parole chiave: cluster, politica dei cluster, approccio triple-helix, sistemi adattivi complessi.Keywords: cluster, cluster policy, triple helix approach, complex adaptive systems.


2017 ◽  
Vol 33 (2) ◽  
pp. 217
Author(s):  
Widya Fitriana

Agricultural sector as a main contributor to GDP formation in West Sumatera is required to be able to diversify its business in order to highest achieving economic and social development. One diversified agricultural business prospective to be developed is agro-tourism. The development of agro-tourism requires collaboration and synergy between academician, businessman and government as known as triple helix actors. This study is designed with aim to (i) map the agro-tourism potential in west Sumatera; (ii) analyze the role of each actors, so they may take action in accelerating Agro-tourism development. This research uses observation, depth interview method, literature study and focus group discussion. The result shows that agro-tourism in West Sumatra is more prominent of great natural and cultural value, small scale and lack of local facilities. It also requires relatively high level of investment relative to its return. Therefore government support is likely an essential element of agro-tourism development and the effort may be better directed toward consolidating with intellectual and business also.


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