Low-dose radiation induced modification of ROS and apoptosis in thymocytes of whole body irradiated mice

2006 ◽  
Vol 2 (1/2) ◽  
pp. 111 ◽  
Author(s):  
B.N. Pandey ◽  
H.D. Sarma ◽  
D. Shukla ◽  
K.P. Mishra
Keyword(s):  
Low Dose ◽  
Whole Body ◽  
Low Dose Radiation ◽  
Radiation Induced ◽  
Dose Radiation

Low-dose radiation-induced acute pericarditis (AP) in breast cancer patient

2013 ◽  
Vol 18 ◽  
pp. S179-S180 ◽  
Author(s):  
I. Alastuey ◽  
A. Noé ◽  
C. Chiaramello ◽  
S. Montemuiño ◽  
J. Pardo
Keyword(s):  
Breast Cancer ◽  
Cancer Patient ◽  
Breast Cancer Patient ◽  
Low Dose ◽  
Low Dose Radiation ◽  
Acute Pericarditis ◽  
Radiation Induced ◽  
Dose Radiation

scholarly journals Low-Dose Radiation-Induced Senescent Stromal Fibroblasts Render Nearby Breast Cancer Cells Radioresistant

2009 ◽  
Vol 172 (3) ◽  
pp. 306-313 ◽  
Author(s):  
Kelvin K. C. Tsai ◽  
Jeremy Stuart ◽  
Yao-Yu Eric Chuang ◽  
John B. Little ◽  
Zhi-Min Yuan
Keyword(s):  
Breast Cancer ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Low Dose ◽  
Low Dose Radiation ◽  
Stromal Fibroblasts ◽  
Radiation Induced ◽  
Dose Radiation

scholarly journals Effects of low dose radiation on immune cells subsets and cytokines in mice

2020 ◽  
Vol 9 (3) ◽  
pp. 249-262
Author(s):  
Xiaochang Liu ◽  
Zheng Liu ◽  
Duo Wang ◽  
Yang Han ◽  
Sai Hu ◽  
...  
Keyword(s):  
Immune System ◽  
Immune Cells ◽  
Low Dose ◽  
White Blood Cells ◽  
Whole Body ◽  
Low Dose Radiation ◽  
Dose Irradiation ◽  
Significant Difference ◽  
Dose Radiation

Abstract Whole-body exposure to low-dose radiation due to diagnostic imaging procedures, occupational hazards and radiation accidents is a source of concern. In this study, we analyzed the effects of single and long-term low-dose irradiation on the immune system. Male Balb/c mice received a single whole-body dose of irradiation (0.01, 0.05, 0.2, 0.5 or 1 Gy). For long-term irradiation, mice were irradiated 10 times (total dose of 0.2, 0.5 or 1 Gy) over a period of 6 weeks. Two days after single or long-term irradiation, the numbers of splenic macrophages, natural killer cells and dendritic cells were reduced, and the spleen organ coefficient was decreased. At 2 Days after long-term low-dose irradiation, the number of white blood cells in the peripheral blood of the mice decreased. Between 7 and 14 Days after long-term low-dose irradiation, the number of immune cells in the thymus and spleen began to increase and then stabilized. Th1/Th2 cytokines and reactive oxygen species-related proteins first decreased and then increased to a plateau. Our results show a significant difference in the effects of single and long-term low-dose irradiation on the immune system.

scholarly journals Low-dose radiation-induced apoptosis in human leukemia K562 cells through mitochondrial pathways

2014 ◽  
Vol 10 (3) ◽  
pp. 1569-1575 ◽  
Author(s):  
YONG XIN ◽  
HAI-BIN ZHANG ◽  
TIAN-YOU TANG ◽  
GUI-HONG LIU ◽  
JIAN-SHE WANG ◽  
...  
Keyword(s):  
Low Dose ◽  
K562 Cells ◽  
Human Leukemia ◽  
Low Dose Radiation ◽  
Radiation Induced ◽  
Induced Apoptosis ◽  
Dose Radiation ◽  
Human Leukemia K562 Cells

An Adoptive Transfer Method to Detect Low-Dose Radiation-Induced Bystander EffectsIn Vivo

2010 ◽  
Vol 173 (2) ◽  
pp. 125-137 ◽  
Author(s):  
Benjamin J. Blyth ◽  
Edouard I. Azzam ◽  
Roger W. Howell ◽  
Rebecca J. Ormsby ◽  
Alexander H. Staudacher ◽  
...  
Keyword(s):  
Adoptive Transfer ◽  
Low Dose ◽  
Low Dose Radiation ◽  
Radiation Induced ◽  
Transfer Method ◽  
Dose Radiation

Meningiomas after Radiotherapy for Tinea Capitis - Still No History

1998 ◽  
Vol 84 (1) ◽  
pp. 65-68 ◽  
Author(s):  
Lea Pollak ◽  
Natalio Walach ◽  
Ruth Gur ◽  
Juana Schiffer
Keyword(s):  
Recurrence Rate ◽  
Tinea Capitis ◽  
Low Dose ◽  
English Literature ◽  
Low Dose Radiation ◽  
Female Ratio ◽  
Intracranial Meningiomas ◽  
Radiation Induced ◽  
The Mean ◽  
Dose Radiation

Aims and background To review the clinical, radiological and histological findings of 19 patients with radiation-induced intracranial meningiomas treated at our neurosurgical department between 1981 and 1996. Method The records of 18 patients with intracranial meningiomas who underwent low-dose radiation for tinea capitis in childhood, and of one patient irradiated for pituitary adenoma, were analyzed in respect of the previously reported features of postradiation meningiomas. Results The mean age of the patients with low-dose radiation-induced meningiomas was 58 years and the mean shortest onset latency was 48 years. The male to female ratio was 1.1:1. Forty-seven percent of patients presented with mental changes and/or focal neurological signs, 21% with signs of increased intracranial pressure and 26% with seizures. Calvarial location of the meningiomas was found in 54% of patients and in one patient the tumor arose from the skull base. Multiple tumors were present in 15% of patients and 29% of the meningiomas displayed malignant features on histological examination. A significantly lower meningioma recurrence rate was found in our series compared to the recurrence rate in the reported series of postradiation meningiomas. Five patients had a history of a second neoplasm other than meningioma. Conclusion Our series of low-dose radiation-induced meningiomas represents one of the largest of its kind in the English literature. The patients did not differ substantially in sex ratio, tumor localization, multiplicity and histological features from the previously reported postradiation meningioma patients, except for the significantly lower tumor recurrence rate. It would seem that over the next years we will be further witnessing the deleterious effects of low-dose radiation administered in childhood.

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