A novel device for detection of soft tissue inflammation: dynamic behaviour of a functionally graded AFM cantilever

Author(s):  
Keikhosrow Firoozbakhsh ◽  
Mohammad Taghi Ahmadian ◽  
Masoud Rahaeifard ◽  
Mohammad Hossain Kahrobaiyan
2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Alexander Pfeil ◽  
Karl F. Drummer ◽  
Joachim Böttcher ◽  
Christian Jung ◽  
Peter Oelzner ◽  
...  

Objective. The aim of this study was to visualize soft tissue inflammation using FOI on patients with Systemic Sclerosis (SSc) characterized by SSc-related Raynaud’s phenomenon and to detect the therapeutic response to treatment with iloprost or alprostadil.Methods. Twenty-one patients with SSc and Raynaud’s phenomenon and twenty-six healthy controls were prospectively included. The SSc patients were intravenously treated with iloprost or alprostadil over seven days. FOI was performed at baseline and after seven days using an intravenous application of indocyanine green (ICG). The hands were divided into nineteen segments per hand. All segments were quantitatively evaluated to determine changes in ICG.Results. The sensitivity and specificity of FOI in the detection of ICG enhancement in patients with SSc were 95% versus 96%. At baseline, 31.5% hand segments showed ICG enhancement. After seven days of either iloprost or alprostadil therapy a significant reduction in the ICG was observed which ranged from 40.9% to 24.7%.Conclusion. The study demonstrates that the FOI technique is able to visualize soft-tissue inflammation with both high sensitivity and specificity. The anti-inflammatory therapeutic effects of iloprost were slightly stronger than alprostadil. FOI offers promising benefits in the diagnosis and therapy of patients with SSc-associated Raynaud’s phenomenon.


2008 ◽  
Vol 6 (6) ◽  
pp. 481-482
Author(s):  
Balakrishnan Saravanan ◽  
Elanchezian Ranganathan ◽  
Andrew Neil Hopper ◽  
Michael Howard Jamison

2013 ◽  
Vol 13 (9) ◽  
pp. S72-S73 ◽  
Author(s):  
Kevin Phan ◽  
Chengjie Xiong ◽  
Michael D. Daubs ◽  
Haijun Tian ◽  
Scott R. Montgomery ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
pp. 55
Author(s):  
Tamar Sanikidze ◽  
Irakli Chkhikvishvili ◽  
Nana Kipiani ◽  
Samson Mghebrishvili ◽  
Irina Barbakadze ◽  
...  

Background: Recovery of dental arch defects, related to insertion of a foreign bodies into the oral cavity, and the impact of mechanical pressure, allergic-toxic effects, and the related inflammatory and degenerative processes is one of the most urgent problems in dentistry.The purpose of the study was to evaluate the efficacy of Georgian bean extract tincture as mouthwash for patients using a lever system to correct deformities of the jaw and teeth.Methods: Twenty-eight patients (aged 12-25 years) with deformities of the jaw and teeth were studied. Patients were examined 6-8 months after the bracket system was installed, and before and after the use of tincture mouthwash for 10 days. Patients were randomly divided into 2 groups: the control group for the mouthwash used standard tincture ("Octenidol" Schulke and Mayr -Germany); the patients of the experimental group used tincture made from the Georgian legume crop extracts (GLCE). Before and after the use of both types of tincture, the data were taken for calculation of Schiller Pisarev's test (SPT), Papillary-Marginal Alveolar (PMA) index, and the oral hygiene index (OHI). Saliva was collected in a glass tube without stimulation, on an empty stomach. The content of cytokines IL-1β, IL-10 in saliva was determined by the ELISA kit.Results: The study demonstrated significant positive clinical efficacy of the mouthwash tincture prepared from the GLCE which increases the resistance of dental tissue. This was revealed by significantly lower values of OHI, PMA index, SPT and increased content of IL-10 in saliva.This data indicates that tincture prepared from the Georgian legume crop extracts, which is designed to increase the stability of oral tissue, does promote an increase in resistance to the aggressive mechanical pressing.Conclusion: Tincture from the GLCE is characterized by a much stronger anti-inflammatory effect than standard tincture "Octenidol" (Schulke and Mayr -Germany) used against inflammation of the oral cavity soft tissue. This allows us to recommend the tincture from the GLCE for the treatment and prevention of inflammatory processes in the oral cavity soft tissue.Keywords: Georgian legumes crop extracts (GLCE), oral cavity soft tissue inflammation, Hygiene Index, PMA index, Schiller Pisarev's test.


2020 ◽  
Author(s):  
O Ebeling ◽  
T Sutter ◽  
R Radler ◽  
T Panidis ◽  
L Limbach ◽  
...  

2008 ◽  
Vol 69 (5) ◽  
pp. 639-646 ◽  
Author(s):  
Lauren G. Kleine ◽  
Mauricio Solano ◽  
Mary Rusckowski ◽  
Kathleen E. Hunt ◽  
Karen L. Johnson ◽  
...  

2004 ◽  
Vol 53 (7) ◽  
Author(s):  
E.A. Romero-Sandoval ◽  
M. Alique ◽  
V. Moreno-Manzano ◽  
C. Molina ◽  
F.J. Lucio ◽  
...  

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