scholarly journals Brain grey-matter volume alteration in adult patients with bipolar disorder under different conditions: a voxel-based meta-analysis

2019 ◽  
Vol 44 (2) ◽  
pp. 89-101 ◽  
Author(s):  
Xiuli Wang ◽  
Qiang Luo ◽  
Fangfang Tian ◽  
Bochao Cheng ◽  
Lihua Qiu ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Grey Matter ◽  
Meta Analysis ◽  
Adult Patients ◽  
Grey Matter Volume ◽  
Matter Volume

scholarly journals Convergent and divergent brain structural and functional abnormalities associated with developmental dyslexia

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Xiaohui Yan ◽  
Ke Jiang ◽  
Hui Li ◽  
Ziyi Wang ◽  
Kyle Perkins ◽  
...  
Keyword(s):  
Developmental Dyslexia ◽  
Grey Matter ◽  
Meta Analysis ◽  
Inferior Frontal Gyrus ◽  
Brain Activation ◽  
Superior Temporal Gyrus ◽  
Brain Regions ◽  
Middle Temporal Gyrus ◽  
Grey Matter Volume ◽  
Matter Volume

Brain abnormalities in the reading network have been repeatedly reported in individuals with developmental dyslexia (DD); however, it is still not totally understood where the structural and functional abnormalities are consistent/inconsistent across languages. In the current multimodal meta-analysis, we found convergent structural and functional alterations in the left superior temporal gyrus across languages, suggesting a neural signature of DD. We found greater reduction in grey matter volume and brain activation in the left inferior frontal gyrus in morpho-syllabic languages (e.g. Chinese) than in alphabetic languages, and greater reduction in brain activation in the left middle temporal gyrus and fusiform gyrus in alphabetic languages than in morpho-syllabic languages. These language differences are explained as consequences of being DD while learning a specific language. In addition, we also found brain regions that showed increased grey matter volume and brain activation, presumably suggesting compensations and brain regions that showed inconsistent alterations in brain structure and function. Our study provides important insights about the etiology of DD from a cross-linguistic perspective with considerations of consistency/inconsistency between structural and functional alterations.

scholarly journals Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorder

2009 ◽  
Vol 194 (5) ◽  
pp. 426-433 ◽  
Author(s):  
Alex Fornito ◽  
Murat Yücel ◽  
Stephen J. Wood ◽  
Andreas Bechdolf ◽  
Simon Carter ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Anterior Cingulate Cortex ◽  
Grey Matter ◽  
Cingulate Cortex ◽  
First Episode Psychosis ◽  
Anterior Cingulate ◽  
First Episode ◽  
Grey Matter Volume ◽  
Matter Volume ◽  
Episode Psychosis

BackgroundThe anterior cingulate cortex is frequently implicated in the pathophysiology of bipolar disorder, but magnetic resonance imaging (MRI) studies have reported variable findings owing to a reliance on patient samples with chronic illness and to limited appreciation of the region's heterogeneity.AimsTo characterise anterior cingulate cortex abnormalities in patients with bipolar disorder experiencing their first episode of psychosis while accounting for regional anatomical variability.MethodGrey matter volume, surface area and cortical thickness were measured in six anterior cingulate cortex subregions per hemisphere using MRI scans acquired from 26 patients with bipolar I disorder experiencing first-episode psychosis and 26 healthy controls matched for age, gender and regional morphological variability.ResultsRelative to controls, male patients displayed increased thickness in the right subcallosal limbic anterior cingulate cortex. No significant differences were identified in females for grey matter volume or surface area measures. The findings were not attributable to medication effects.ConclusionsThese data suggest that first-episode psychosis in bipolar disorder is associated with a gender-specific, right-lateralised thickness increase in anterior cingulate cortex subregions known to play a role in regulating physiological stress responses.

Lower Grey Matter Volume and Emotion Regulation in Young Adults With Bipolar Disorder and a History of Psychosis

2020 ◽  
Vol 87 (9) ◽  
pp. S194
Author(s):  
Vanessa Le ◽  
Valeria Tretyak ◽  
Dylan Kirsch ◽  
Alex Preston ◽  
Stephen Strakowski ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Young Adults ◽  
Emotion Regulation ◽  
Grey Matter ◽  
Grey Matter Volume ◽  
Matter Volume ◽  
History Of

scholarly journals Exploring the neuroanatomical bases of psychotic features in bipolar disorder

2017 ◽  
Vol 26 (4) ◽  
pp. 358-363 ◽  
Author(s):  
E. Maggioni ◽  
A. C. Altamura ◽  
P. Brambilla
Keyword(s):  
Bipolar Disorder ◽  
Grey Matter ◽  
Psychotic Disorders ◽  
Psychotic Symptoms ◽  
Grey Matter Volume ◽  
Healthy Controls ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
Matter Volume ◽  
Psychotic Features

Although bipolar disorder (BD) is traditionally conceptualised as one diagnostic entity, the heterogeneity of pathophysiological manifestations in BD suggests the need to classify the subtypes of the illness based on neural markers. Specifically, the presence of psychotic symptoms seems to be relevant for the clinical outcome and may have specific neuroanatomical bases. The main objective of the present review was to assess whether the distinction between psychotic BD (PBD) and non-psychotic BD (NPBD) can improve the identification of the neurobiological markers of this complex illness. To this end, we summarised the findings from the magnetic resonance imaging studies that explored the cerebral correlates of psychosis in BD in terms of grey matter volume (GMV). Overall, the results suggest the presence of peculiar GMV differences between PBD and NPBD. Specifically, psychosis in BD seems to be associated with cortical GMV deficits compared with both healthy controls and NPBD, mainly in the frontal region. Conversely, NPBD patients showed GMV deficits in selective regions of the basal ganglia when compared with the other groups. Taken together, this evidence confirms the importance to classify BD based on the psychotic dimension, which may have a specific neurobiological architecture that partially overlaps across multiple psychotic disorders.

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