scholarly journals Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest pain

2012 ◽  
Vol 184 (5) ◽  
pp. E260-E268 ◽  
Author(s):  
S. J. Aldous ◽  
M. Richards ◽  
L. Cullen ◽  
R. Troughton ◽  
M. Than
Keyword(s):  
Chest Pain ◽  
Troponin T ◽  
High Sensitivity ◽  
Early Measurement ◽  
High Sensitivity Troponin ◽  
Prognostic Utility ◽  
High Sensitivity Troponin T

scholarly journals Validation of an accelerated high‐sensitivity troponin T assay protocol in an Australian cohort with chest pain

2014 ◽  
Vol 200 (3) ◽  
pp. 161-165 ◽  
Author(s):  
William A Parsonage ◽  
Jaimi H Greenslade ◽  
Christopher J Hammett ◽  
Arvin Lamanna ◽  
Jillian R Tate ◽  
...  
Keyword(s):  
Chest Pain ◽  
Troponin T ◽  
High Sensitivity ◽  
High Sensitivity Troponin ◽  
Australian Cohort ◽  
High Sensitivity Troponin T ◽  
Assay Protocol

Usefulness of high-sensitivity troponin T for the evaluation of patients with acute chest pain and no or minimal myocardial damage

2012 ◽  
Vol 164 (2) ◽  
pp. 194-200.e1 ◽  
Author(s):  
Juan Sanchis ◽  
Alfredo Bardají ◽  
Xavier Bosch ◽  
Pablo Loma-Osorio ◽  
Francisco Marín ◽  
...  
Keyword(s):  
Chest Pain ◽  
Troponin T ◽  
Acute Chest Pain ◽  
Myocardial Damage ◽  
High Sensitivity ◽  
High Sensitivity Troponin ◽  
High Sensitivity Troponin T

scholarly journals LO97: Validation of the HEART score in Canadian emergency department chest pain patients using a high-sensitivity troponin T assay

CJEM ◽  
2017 ◽  
Vol 19 (S1) ◽  
pp. S61-S62 ◽  
Author(s):  
J. Andruchow ◽  
A. McRae ◽  
T. Abedin ◽  
D. Wang ◽  
G. Innes ◽  
...  
Keyword(s):  
Emergency Department ◽  
Chest Pain ◽  
Troponin T ◽  
High Sensitivity ◽  
Low Risk ◽  
Moderate Risk ◽  
Heart Score ◽  
High Sensitivity Troponin ◽  
High Sensitivity Troponin T ◽  
Pain Patients

Introduction: The HEART score is a validated tool created to risk stratify emergency department (ED) chest pain patients using 5 simple criteria (History, ECG findings, Age, Risk factors, and Troponin). Several studies have demonstrated the superiority of HEART over other well known risk stratification tools in identifying low risk chest pain patients suitable for early discharge. All but one of these studies used conventional troponin assays, and most were conducted in European populations. This study aims to validate the HEART score using a high-sensitivity troponin T assay in a Canadian population. Methods: This prospective cohort study was conducted at a single urban tertiary centre and regional percutaneous coronary intervention site in Calgary, Alberta. Patients were eligible for enrolment if they presented to the ED with chest pain, were age 25-years or older and required biomarker testing to rule out AMI at the discretion of the attending emergency physician. Patients were excluded if they had clear acute ischemic ECG changes, new arrhythmia or renal failure requiring hemodialysis. Clinical data were recorded by the emergency physician at the time of enrolment and outcomes were obtained from administrative data. High-sensitivity troponin-T (Roche Elecsys hs-cTnT) results were obtained in all patients at presentation. The primary outcome was AMI within 30-days of ED visit, the secondary outcome was 30-day major adverse cardiac events (MACE). Results: A total of 984 ED patients with complete HEART scores were enrolled from August 2014 to September 2016. The 30-day incidence of AMI and MACE in the overall population was 3.3% and 20.6%, respectively. HEART scores were predictive of 30-day AMI incidence: low risk (0-3): 0.77% (95%CI 0.0-1.5%), moderate risk (4-6): 4.3% (95%CI 2.3-6.2%) and high risk (7-10): 12.2% (95%CI 5.5-19.0%). HEART scores also predicted 30-day MACE: low risk (0-3): 5.0% (95%CI 3.1-6.9%), moderate risk (4-6): 31.8% (95%CI 27.2-36.4%) and high-risk (7-10): 61.4% (95%CI 51.2-71.5%). More than half of patients, 522 (53.0%) could be identified as low risk based on the HEART score using a single troponin result. Conclusion: Using a single high-sensitivity troponin result collected at ED presentation, the HEART score can rapidly and effectively identify more than half of ED chest pain patients as low risk for 30-day AMI, but is less sensitive for 30-day MACE.

scholarly journals 5 Pilot of a Modified HEART Score and Serial High Sensitivity Troponin T Pathway to Reduce Chest Pain Observations

2017 ◽  
Vol 70 (4) ◽  
pp. S2-S3
Author(s):  
R.S. Engineer ◽  
B.W. Marshall ◽  
J.T. Milk ◽  
E.L. Simon ◽  
C.M. Smalley ◽  
...  
Keyword(s):  
Chest Pain ◽  
Troponin T ◽  
High Sensitivity ◽  
Heart Score ◽  
High Sensitivity Troponin ◽  
High Sensitivity Troponin T
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