scholarly journals Outcome reporting bias in randomized trials funded by the Canadian Institutes of Health Research

2004 ◽  
Vol 171 (7) ◽  
pp. 735-740 ◽  
Author(s):  
A.-W. Chan
2020 ◽  
Author(s):  
Lucas Helal ◽  
Gabriel Gonçalves da Costa ◽  
Charles Phillipe de Lucena Alves ◽  
Barbara Okabaisse Luizetti ◽  
Guilherme Weiss Freccia ◽  
...  

This pre-print refers to a protocol of a study which intends to explore outcome reporting bias in an extensive sample of the non-pharmacological literature and also to access the completeness of reporting of outcomes of such trials.


Biostatistics ◽  
2013 ◽  
Vol 15 (2) ◽  
pp. 370-383 ◽  
Author(s):  
J. Copas ◽  
K. Dwan ◽  
J. Kirkham ◽  
P. Williamson

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180986 ◽  
Author(s):  
Benjamin Howard ◽  
Jared T. Scott ◽  
Mark Blubaugh ◽  
Brie Roepke ◽  
Caleb Scheckel ◽  
...  

2017 ◽  
Vol 28 (3) ◽  
pp. 889-903 ◽  
Author(s):  
John Copas ◽  
Anthony Marson ◽  
Paula Williamson ◽  
Jamie Kirkham

Outcome reporting bias occurs when outcomes in research studies are selectively reported, the selection being influenced by the study results. For benefit outcomes, we have shown how risk assessments using the Outcome Reporting Bias in Trials risk classification scale can be used to calculate bias-adjusted treatment effect estimates. This paper presents a new and simpler version of the benefits method, and shows how it can be extended to cover the partial reporting and non-reporting of harm outcomes. Our motivating example is a Cochrane systematic review of 12 studies of Topiramate add-on therapy for drug-resistant partial epilepsy. Bias adjustments for partially reported or unreported outcomes suggest that the review has overestimated the benefits and underestimated the harms of the test treatment.


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