scholarly journals The evolving TNM cancer staging system: an essential component of cancer care

2006 ◽  
Vol 174 (2) ◽  
pp. 155-156 ◽  
Author(s):  
J. Brierley
Keyword(s):  
Cancer Care ◽  
Staging System ◽  
Cancer Staging ◽  
Essential Component

Final Version of the American Joint Committee on Cancer Staging System for Cutaneous Melanoma

2001 ◽  
Vol 19 (16) ◽  
pp. 3635-3648 ◽  
Author(s):  
Charles M. Balch ◽  
Antonio C. Buzaid ◽  
Seng-Jaw Soong ◽  
Michael B. Atkins ◽  
Natale Cascinelli ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Elevated Serum ◽  
Primary Melanoma ◽  
Staging System ◽  
Distant Metastases ◽  
Lactic Dehydrogenase ◽  
Cancer Staging ◽  
Sixth Edition ◽  
Stage Grouping ◽  
American Joint Committee

PURPOSE: To revise the staging system for cutaneous melanoma under the auspices of the American Joint Committee on Cancer (AJCC). MATERIALS AND METHODS: The prognostic factors analysis described in the companion publication (this issue), as well as evidence from the published literature, was used to assemble the tumor-node-metastasis criteria and stage grouping for the melanoma staging system. RESULTS: Major changes include (1) melanoma thickness and ulceration but not level of invasion to be used in the T category (except for T1 melanomas); (2) the number of metastatic lymph nodes rather than their gross dimensions and the delineation of clinically occult (ie, microscopic) versus clinically apparent (ie, macroscopic) nodal metastases to be used in the N category; (3) the site of distant metastases and the presence of elevated serum lactic dehydrogenase to be used in the M category; (4) an upstaging of all patients with stage I, II, and III disease when a primary melanoma is ulcerated; (5) a merging of satellite metastases around a primary melanoma and in-transit metastases into a single staging entity that is grouped into stage III disease; and (6) a new convention for defining clinical and pathologic staging so as to take into account the staging information gained from intraoperative lymphatic mapping and sentinel node biopsy. CONCLUSION: This revision will become official with publication of the sixth edition of the AJCC Cancer Staging Manual in the year 2002.

scholarly journals Application of the revised lung cancer staging system (IASLC Staging Project) to a cancer center population

2009 ◽  
Vol 138 (2) ◽  
pp. 412-418.e2 ◽  
Author(s):  
Edmund S. Kassis ◽  
Ara A. Vaporciyan ◽  
Stephen G. Swisher ◽  
Arlene M. Correa ◽  
B. Nebiyou Bekele ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Staging System ◽  
Cancer Staging ◽  
Cancer Center

Providing cessation treatment to every oncology patient who smokes: An essential component of cancer care

Cancer ◽  
2021 ◽  
Author(s):  
Michael C. Fiore ◽  
Timothy B. Baker ◽  
Margaret B. Nolan ◽  
Hamid Emamekhoo
Keyword(s):  
Cancer Care ◽  
Oncology Patient ◽  
Essential Component ◽  
Cessation Treatment

scholarly journals A Critical Reappraisal of Primary and Recurrent Advanced Laryngeal Cancer Staging

2018 ◽  
Vol 128 (1) ◽  
pp. 36-43 ◽  
Author(s):  
Luca Giovanni Locatello ◽  
Michele Pietragalla ◽  
Cecilia Taverna ◽  
Luigi Bonasera ◽  
Daniela Massi ◽  
...  
Keyword(s):  
Squamous Cell ◽  
Vocal Fold ◽  
Thyroid Cartilage ◽  
Case Series ◽  
Staging System ◽  
Cancer Staging ◽  
Arytenoid Cartilage ◽  
Posterior Commissure ◽  
Diagnostic Pitfall ◽  
Pathologic Findings

Objectives: Laryngeal squamous cell carcinoma (LSCC) can involve different anatomic subunits with peculiar surgical and prognostic implications. Despite conflicting outcomes for the same stage of disease, the current staging system considers different lesions in a single cluster. The aim of this study was to critically discuss clinical and pathologic staging of primary and recurrent advanced LSCC in order to define current staging pitfalls that impede a precise and tailored treatment strategy. Methods: Thirty patients who underwent total laryngectomy in the past 3 years for primary and recurrent advanced squamous cell LSCC were analyzed, comparing endoscopic, imaging, and pathologic findings. Involvement of the different laryngeal subunits, vocal-fold motility, and spreading pattern of the tumor were blindly analyzed. The diagnostic accuracy and differences between clinicoradiologic and pathologic findings were studied with standard statistical analysis. Results: Discordant staging was performed in 10% of patients, and thyroid and arytenoid cartilage were the major diagnostic pitfalls. Microscopic arytenoid involvement was significantly more present in case of vocal-fold fixation ( P = .028). Upstaging was influenced by paraglottic and pre-epiglottic space cancer involvement, posterior commissure, subglottic region, arytenoid cartilage, and penetration of thyroid cartilage; on the contrary, involvement of the inner cortex or extralaryngeal spread tended to be down-staged. Radiation-failed tumors less frequently involved the posterior third of the paraglottic space ( P = .022) and showed a significantly worse pattern of invasion ( P < .001). Conclusions: Even with the most recent technologies, 1 in 10 patients with advanced LSCC in this case series was differently staged on clinical examination, with cartilage involvement representing the main diagnostic pitfall.

Sign in / Sign up

Export Citation Format

Share Document