scholarly journals Information on the Internet about colorectal cancer: patient attitude and potential toward Web browsing. A prospective observational study

2011 ◽  
Vol 54 (5) ◽  
pp. 339-343 ◽  
Author(s):  
Muhammad Sajid
Keyword(s):  
Colorectal Cancer ◽  
Observational Study ◽  
Cancer Patient ◽  
Prospective Observational Study ◽  
Colorectal Cancer Patient ◽  
The Internet ◽  
Web Browsing ◽  
Patient Attitude

Colorectal cancer patient utilization of an internet based clinical trials matching system

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 3624-3624
Author(s):  
C. Bui ◽  
M. Hampshire ◽  
C. Vachani ◽  
J. Metz
Keyword(s):  
Colorectal Cancer ◽  
Clinical Trials ◽  
Cancer Patient ◽  
Cancer Patients ◽  
Call Center ◽  
Colorectal Cancer Patient ◽  
The Internet ◽  
Specific Information ◽  
Web Based ◽  
Colorectal Cancer Patients

3624 Background: Colorectal cancer patients are increasingly looking to the Internet for information on clinical trials; however, services offering clinical trials recruitment have not been well defined. This study describes one of the first web-based cancer clinical trials matching resources and the demographics of the colorectal cancer patient user base. Methods: Oncolink ( http://www.oncolink.org ) is the web-based educational resource at the University of Pennsylvania and serves between 1.5–2 million pages per month to over 385,000 unique IP addresses. Oncolink, in conjunction with EmergingMed (New York, NY), launched one of the first clinical trials matching resources on the Internet. Patients input demographic and tumor-specific information via secure Internet-only registration or via the Internet with assistance from a call center, to match to trials. As of 12/2005, there were 112 total colorectal trials in the database. Results: Between 12/2000 and 9/2005 a total of 41,970 individual profiles were created, with 3289 (7.8%) by colorectal cancer patients. Other GI tumors accounted for 15% of profiles. Of the 3289 patients, 54% were male and 46% were female, and the median age was 55 (range 19–96). Most patients reported their disease as having spread to another organ (62%) or to lymph nodes (15.4%). Most patients were previously treated with surgery (81%), radiation (26%), chemotherapy (74%), and/or biological therapies (21%) (bevacizumab, cetuximab, interferon or interleukin). Patients who used the call center with the Internet were more likely to apply for enrollment in a clinical trial after review of the matches (77% vs. 10%, p<0.001). The median number of trial matches in the system was 7 per patient. Of the 3289 colorectal patients, 681 patients (21%) went on to apply for enrollment to trials based on their matches. Conclusions: This report demonstrates that a significant percentage of colorectal cancer patients are willing to use the Internet to match to clinical trials. Contact with a call center greatly increases the likelihood of application to trials. Internet based clinical trials resources should maintain options for personal communication to increase the likelihood of enrollment to clinical trials. No significant financial relationships to disclose.

scholarly journals Altered Preoperative Nutritional Status in Colorectal Cancer: A Not So Infrequent Issue

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Javier Páramo-Zunzunegui ◽  
Araceli Ramos-Carrasco ◽  
Marcos Alonso-García ◽  
Rosa Cuberes-Montserrat ◽  
Gil Rodríguez-Caravaca ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Weight Loss ◽  
Observational Study ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Prospective Observational Study ◽  
Colorectal Neoplasia ◽  
Nutritional Risk ◽  
A Value ◽  
Asymptomatic Patients

Introduction. Malnutrition and weight loss in cancer patients is a common problem that affects the prognosis of the disease. In the case of CRC, malnutrition rates range between 30 and 60%. Objectives. Description of the preoperative nutritional status of patients diagnosed with colorectal neoplasia who will undergo surgery. Materials and Methods. A prospective observational study is performed. Results. Of 234 patients studied, we observed that 139 (59%) had some degree of nutritional risk. Of all of them, 44.9% (N = 47) had 1-2 points according to MUST and 25% (N = 27) had more than 2 points. No differences were found when studying nutritional risk according to the location of the neoplasm. It was observed that 2.15% of the patients were underweight, 51% overweight, and 23% obese. 19.4% of patients lost less than 5 kg in the 3–6 months prior to diagnosis, 20.7% lost between 5 and 10 kg, and 2.1% lost more than 10 kg. In asymptomatic patients, the weight loss was lower than in symptomatic patients, loss <5 kg, 8.2% vs. 22.8%, and loss 5–10 kg, 16.2% vs. 29.3%, with a value of p = 0.016 . 5% (N = 7) of the patients had hypoalbuminemia record. 16.5% (N = 23) had some degree of prealbumin deficiency and 20.9% (N = 29) of hypoproteinemia. Symptomatic patients had more frequent analytical alterations, 1-2 altered parameters in 48.8% (N = 20) of asymptomatic vs. 61.2% (N = 22) in the symptomatic, p = 0.049 .

Abstract 1912: An explorative analysis ofERCC1/ERCC4copy number alterations in a chemonaive stage III colorectal cancer patient cohort.

2013 ◽  
Author(s):  
David H. Smith ◽  
Niels F. Jensen ◽  
Ib J. Christensen ◽  
Sven Müller ◽  
Hans J. Nielsen ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patient ◽  
Colorectal Cancer Patient ◽  
Stage Iii ◽  
Patient Cohort

VEGFR1+ Metastasis–Associated Macrophages Contribute to Metastatic Angiogenesis and Influence Colorectal Cancer Patient Outcome

2019 ◽  
Vol 25 (18) ◽  
pp. 5674-5685 ◽  
Author(s):  
Aida Freire Valls ◽  
Karl Knipper ◽  
Evangelia Giannakouri ◽  
Víctor Sarachaga ◽  
Sascha Hinterkopf ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Patient Outcome ◽  
Cancer Patient ◽  
Colorectal Cancer Patient
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