scholarly journals Intra‐rater reliability of leg blood flow during dynamic exercise using Doppler ultrasound

2021 ◽  
Vol 9 (19) ◽  
Author(s):  
Sachin B. Amin ◽  
Hendrik Mugele ◽  
Florian E. Dobler ◽  
Kyohei Marume ◽  
Jonathan P. Moore ◽  
...  
Keyword(s):  
Blood Flow ◽  
Doppler Ultrasound ◽  
Dynamic Exercise ◽  
Rater Reliability ◽  
Leg Blood Flow

Intra- and Inter-rater Reliability of Peripheral Arterial Blood Flow Velocity by Means of Doppler Ultrasound

2017 ◽  
Vol 40 (4) ◽  
pp. 236-240 ◽  
Author(s):  
Elaine Caldeira de Oliveira Guirro ◽  
Gabriella de Paula Marcondes Ferreira Leite ◽  
Almir Vieira Dibai-Filho ◽  
Nathalia Cristina de Souza Borges ◽  
Rinaldo Roberto de Jesus Guirro
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Doppler Ultrasound ◽  
Blood Flow Velocity ◽  
Arterial Blood Flow ◽  
Rater Reliability ◽  
Arterial Blood ◽  
Peripheral Arterial

scholarly journals QUANTITATIVE LEG BLOOD FLOW BY DOPPLER ULTRASOUND IN UPRIGHT AND SUPINE EXERCISE 818

1997 ◽  
Vol 29 (Supplement) ◽  
pp. 142
Author(s):  
M. J. MacDonald ◽  
M. E. Tschakovsky ◽  
J. K. Shoemaker ◽  
R. L. Hughson
Keyword(s):  
Blood Flow ◽  
Doppler Ultrasound ◽  
Leg Blood Flow

Impaired leg vasodilation during dynamic exercise in healthy older women

2003 ◽  
Vol 95 (5) ◽  
pp. 1963-1970 ◽  
Author(s):  
David N. Proctor ◽  
Dennis W. Koch ◽  
Sean C. Newcomer ◽  
Khoi U. Le ◽  
Urs A. Leuenberger
Keyword(s):  
Blood Flow ◽  
Older Women ◽  
Femoral Vein ◽  
Venous Pressure ◽  
Constant Load ◽  
Dynamic Exercise ◽  
Leg Blood Flow ◽  
Leg Cycle Ergometry ◽  
Leg Cycling ◽  
Exercise Induced

The purpose of the present study was to test the hypothesis that leg blood flow responses during leg cycle ergometry are reduced with age in healthy non-estrogen-replaced women. Thirteen younger (20-27 yr) and thirteen older (61-71 yr) normotensive, non-endurance-trained women performed both graded and constant-load bouts of leg cycling at the same absolute exercise intensities. Leg blood flow (femoral vein thermodilution), mean arterial pressure (MAP; radial artery), mean femoral venous pressure, cardiac output (acetylene rebreathing), and blood O2 contents were measured. Leg blood flow responses at light workloads (20-40 W) were similar in younger and older women. However, at moderate workloads (50-60 W), leg blood flow responses were significantly attenuated in older women. MAP was 20-25 mmHg higher ( P < 0.01) in the older women across all work intensities, and calculated leg vascular conductance (leg blood flow/estimated leg perfusion pressure) was lower ( P < 0.05). Exercise-induced increases in leg arteriovenous O2 difference and O2 extraction were identical between groups ( P > 0.6). Leg O2 uptake was tightly correlated with leg blood flow across all workloads in both subject groups ( r2 = 0.80). These results suggest the ability of healthy older women to undergo limb vasodilation in response to submaximal exercise is impaired and that the legs are a potentially important contributor to the augmented systemic vascular resistance seen during dynamic exercise in older women.

LEG BLOOD FLOW DURING LARGE MUSCLE DYNAMIC EXERCISE

2001 ◽  
Vol 33 (5) ◽  
pp. S209
Author(s):  
K Le ◽  
S Newcomer ◽  
D Koch ◽  
U Leuenberger ◽  
D Proctor
Keyword(s):  
Blood Flow ◽  
Dynamic Exercise ◽  
Leg Blood Flow ◽  
Large Muscle

Reduced leg blood flow during dynamic exercise in older endurance-trained men

1998 ◽  
Vol 85 (1) ◽  
pp. 68-75 ◽  
Author(s):  
David N. Proctor ◽  
Peter H. Shen ◽  
Niki M. Dietz ◽  
Tamara J. Eickhoff ◽  
Lori A. Lawler ◽  
...  
Keyword(s):  
Blood Flow ◽  
Femoral Vein ◽  
Pulmonary Ventilation ◽  
Hemoglobin Concentration ◽  
Older Men ◽  
Dynamic Exercise ◽  
Whole Body ◽  
Vascular Conductance ◽  
Leg Blood Flow ◽  
Ergometer Exercise

It is currently unclear whether aging alters the perfusion of active muscles during large-muscle dynamic exercise in humans. To study this issue, direct measurements of leg blood flow (femoral vein thermodilution) and systemic arterial pressure during submaximal cycle ergometry (70, 140, and 210 W) were compared between six younger (Y; 22–30 yr) and six older (O; 55–68 yr) chronically endurance-trained men. Whole body O2uptake, ventilation, and arterial and femoral venous samples for blood-gas, catecholamine, and lactate determinations were also obtained. Training duration (min/day), estimated leg muscle mass (dual-energy X-ray absorptiometry; Y, 21.5 ± 1.2 vs. O, 19.9 ± 0.9 kg), and blood hemoglobin concentration (Y, 14.9 ± 0.4 vs. O, 14.7 ± 0.2 g/dl) did not significantly differ ( P > 0.05) between groups. Leg blood flow, leg vascular conductance, and femoral venous O2 saturation were ∼20–30% lower in the older men at each work rate (all P < 0.05), despite similar levels of whole body O2 uptake. At 210 W, leg norepinephrine spillover rates and femoral venous lactate concentrations were more than twofold higher in the older men. Pulmonary ventilation was also higher in the older men at 140 (+24%) and 210 (+39%) W. These results indicate that leg blood flow and vascular conductance during cycle ergometer exercise are significantly lower in older endurance-trained men in comparison to their younger counterparts. The mechanisms responsible for this phenomenon and the extent to which they operate in other groups of older subjects deserve further attention.

Leg vasoconstriction during dynamic exercise with reduced cardiac output

1992 ◽  
Vol 73 (5) ◽  
pp. 1838-1846 ◽  
Author(s):  
J. A. Pawelczyk ◽  
B. Hanel ◽  
R. A. Pawelczyk ◽  
J. Warberg ◽  
N. H. Secher
Keyword(s):  
Heart Rate ◽  
Blood Flow ◽  
Cardiac Output ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Dynamic Exercise ◽  
Adrenergic Blockade ◽  
Vascular Conductance ◽  
Leg Blood Flow ◽  
Norepinephrine Spillover

We evaluated whether a reduction in cardiac output during dynamic exercise results in vasoconstriction of active skeletal muscle vasculature. Nine subjects performed four 8-min bouts of cycling exercise at 71 +/- 12 to 145 +/- 13 W (40-84% maximal oxygen uptake). Exercise was repeated after cardioselective (beta 1) adrenergic blockade (0.2 mg/kg metoprolol iv). Leg blood flow and cardiac output were determined with bolus injections of indocyanine green. Femoral arterial and venous pressures were monitored for measurement of heart rate, mean arterial pressure, and calculation of systemic and leg vascular conductance. Leg norepinephrine spillover was used as an index of regional sympathetic activity. During control, the highest heart rate and cardiac output were 171 +/- 3 beats/min and 18.9 +/- 0.9 l/min, respectively. beta 1-Blockade reduced these values to 147 +/- 6 beats/min and 15.3 +/- 0.9 l/min, respectively (P < 0.001). Mean arterial pressure was lower than control during light exercise with beta 1-blockade but did not differ from control with greater exercise intensities. At the highest work rate in the control condition, leg blood flow and vascular conductance were 5.4 +/- 0.3 l/min and 5.2 +/- 0.3 cl.min-1.mmHg-1, respectively, and were reduced during beta 1-blockade to 4.8 +/- 0.4 l/min (P < 0.01) and 4.6 +/- 0.4 cl.min-1.mmHg-1 (P < 0.05). During the same exercise condition leg norepinephrine spillover increased from a control value of 2.64 +/- 1.16 to 5.62 +/- 2.13 nM/min with beta 1-blockade (P < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)

Endothelin-1-mediated vasoconstriction at rest and during dynamic exercise in healthy humans

2007 ◽  
Vol 293 (4) ◽  
pp. H2550-H2556 ◽  
Author(s):  
D. Walter Wray ◽  
Steven K. Nishiyama ◽  
Anthony J. Donato ◽  
Mikael Sander ◽  
Peter D. Wagner ◽  
...  
Keyword(s):  
Blood Flow ◽  
Exercise Intensity ◽  
Muscle Blood Flow ◽  
Knee Extensor ◽  
Dynamic Exercise ◽  
Dependent Manner ◽  
Drug Infusion ◽  
Leg Blood Flow ◽  
Healthy Humans ◽  
Arterial Blood

It is now generally accepted that α-adrenoreceptor-mediated vasoconstriction is attenuated during exercise, but the efficacy of nonadrenergic vasoconstrictor pathways during exercise remains unclear. Thus, in eight young (23 ± 1 yr), healthy volunteers, we contrasted changes in leg blood flow (ultrasound Doppler) before and during intra-arterial infusion of the α1-adrenoreceptor agonist phenylephrine (PE) with that of the nonadrenergic endothelin A (ETA)/ETB receptor agonist ET-1. Heart rate, arterial blood pressure, common femoral artery diameter, and mean blood velocity were measured at rest and during knee-extensor exercise at 20%, 40%, and 60% of maximal work rate (WRmax). Drug infusion rates were adjusted for blood flow to maintain comparable doses across all subjects and conditions. At rest, PE infusion (8 ng·ml−1·min−1) provoked a rapid and significant decrease in leg blood flow (−51 ± 3%) within 2.5 min. Resting ET-1 infusion (40 pg·ml−1·min−1) significantly decreased leg blood flow within 5 min, reaching a maximal vasoconstriction (−34 ± 3%) after 25–30 min of continuous infusion. Compared with rest, an exercise intensity-dependent attenuation to PE-mediated vasoconstriction was observed (−18 ± 5%, −7 ± 2%, and −1 ± 3% change in leg blood flow at 20%, 40%, and 60% of WRmax, respectively). Vasoconstriction in response to ET-1 was also blunted in an exercise intensity-dependent manner (−13 ± 3%, −7 ± 4%, and 2 ± 3% change in leg blood flow at 20%, 40%, and 60% of WRmax, respectively). These findings support a significant contribution of ET-1 and α-adrenergic receptors in the regulation of skeletal muscle blood flow in the human leg at rest and suggest a similar, intensity-dependent “lysis” of peripheral ET and α-adrenergic vasoconstriction during dynamic exercise.

Normal effect of insulin to stimulate leg blood flow in NIDDM

Diabetes ◽  
1995 ◽  
Vol 44 (2) ◽  
pp. 221-226 ◽  
Author(s):  
F. Dela ◽  
J. J. Larsen ◽  
K. J. Mikines ◽  
H. Galbo
Keyword(s):  
Blood Flow ◽  
Leg Blood Flow
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