scholarly journals Effects of lactate administration on mitochondrial enzyme activity and monocarboxylate transporters in mouse skeletal muscle

2019 ◽  
Vol 7 (17) ◽  
Author(s):  
Kenya Takahashi ◽  
Yu Kitaoka ◽  
Yutaka Matsunaga ◽  
Hideo Hatta
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Monocarboxylate Transporters ◽  
Mitochondrial Enzyme ◽  
Mouse Skeletal Muscle

scholarly journals Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study

2012 ◽  
Vol 4 (1) ◽  
pp. 71-77 ◽  
Author(s):  
Bethan E. Phillips ◽  
Kenneth Smith ◽  
Sarah Liptrot ◽  
Philip J. Atherton ◽  
Krishna Varadhan ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Colon Cancer ◽  
Enzyme Activity ◽  
Pilot Study ◽  
Cancer Patients ◽  
Surgical Resection ◽  
Mitochondrial Enzyme

scholarly journals Whole‐body heat stress increases mitochondrial enzyme activity in mice skeletal muscle

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Yuki Tamura ◽  
Yutaka Matsunaga ◽  
Hiroyuki Masuda ◽  
Yumiko Takahashi ◽  
Yuki Takahashi ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Heat Stress ◽  
Whole Body ◽  
Mitochondrial Enzyme ◽  
Whole Body Heat Stress ◽  
Body Heat

Regulation of 5'-aminolevulinate synthase activity in overloaded skeletal muscle

1990 ◽  
Vol 259 (2) ◽  
pp. C310-C314 ◽  
Author(s):  
D. A. Essig ◽  
J. M. Kennedy ◽  
L. A. McNabney
Keyword(s):  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Cytochrome Oxidase ◽  
Weight Bearing ◽  
Mitochondrial Enzyme ◽  
Total Rna ◽  
Aminolevulinate Synthase ◽  
Initial Rise ◽  
Mrna Content ◽  
Chicken Skeletal Muscle

The regulation of the mitochondrial enzyme 5'-aminolevulinate synthase (ALV synthase) activity during chronic weight-bearing activity (overload) in chicken skeletal muscle was investigated. Maximal enzyme activity was increased 2.5- and 4.0-fold after 3 and 7 days of overload. The content of ALV synthase mRNA (ng/mg total RNA) was not changed after 3 days but increased (20%; P less than 0.05) after 7 days of overload. Normalizing the content of ALV synthase mRNA relative to the increase in total RNA indicated that ALV synthase mRNA increased by 1.6- and 2.0-fold at 3 and 7 days, respectively. On this basis, the increase in enzyme activity per gram protein exceeded the increase in mRNA content per gram protein by 60-70%. During overload, the activity of cytochrome oxidase was unchanged after 3 days but increased by 1.5-fold (P less than 0.05) after 7 days of overload. The data indicate that 1) the initial rise in ALV synthase mRNA and activity due to overload occurs in the absence of a prior change in the level of cytochrome oxidase, an enzyme that requires heme for its assembly, and 2) induction of ALV synthase activity is regulated largely by processes at the translational or posttranslational steps.

scholarly journals Intact skeletal muscle mitochondrial enzyme activity but diminished exercise capacity in advanced heart failure patients on optimal medical and device therapy

2013 ◽  
Vol 102 (8) ◽  
pp. 547-554 ◽  
Author(s):  
Holly R. Middlekauff ◽  
M. Anthony Verity ◽  
Tamara B. Horwich ◽  
Gregg C. Fonarow ◽  
Michele A. Hamilton ◽  
...  
Keyword(s):  
Heart Failure ◽  
Skeletal Muscle ◽  
Enzyme Activity ◽  
Exercise Capacity ◽  
Advanced Heart Failure ◽  
Mitochondrial Enzyme ◽  
Device Therapy ◽  
Heart Failure Patients
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