scholarly journals Endothelial colony-forming cell therapy for heart morphological changes after neonatal high oxygen exposure in rats, a model of complications of prematurity

2018 ◽  
Vol 6 (22) ◽  
pp. e13922 ◽  
Author(s):  
Camille Girard-Bock ◽  
Carla C. de Araújo ◽  
Mariane Bertagnolli ◽  
Thuy-An Mai-Vo ◽  
Arul Vadivel ◽  
...  
Keyword(s):  
Cell Therapy ◽  
Morphological Changes ◽  
High Oxygen ◽  
Oxygen Exposure ◽  
Colony Forming Cell

PS 13-03 TRANSIENT NEONATAL HIGH OXYGEN EXPOSURE ACCELERATES ADULT CARDIAC BASELINE AND ANG II-INDUCED PROOXIDATIVE AND PROINFLAMMATORY RESPONSES

2016 ◽  
Vol 34 (Supplement 1) ◽  
pp. e426
Author(s):  
Muhammad Oneeb Rehman Mian ◽  
Fauve Boudreau ◽  
Mariane Bertagnolli ◽  
Marie-Amelie Lukaszewski ◽  
Thuy Mai LUU ◽  
...  
Keyword(s):  
High Oxygen ◽  
Ang Ii ◽  
Oxygen Exposure ◽  
Proinflammatory Responses

scholarly journals Transient Neonatal High Oxygen Exposure Leads to Early Adult Cardiac Dysfunction, Remodeling, and Activation of the Renin–Angiotensin System

Hypertension ◽  
2014 ◽  
Vol 63 (1) ◽  
pp. 143-150 ◽  
Author(s):  
Mariane Bertagnolli ◽  
Fanny Huyard ◽  
Anik Cloutier ◽  
Zackary Anstey ◽  
Julie-Émilie Huot-Marchand ◽  
...  
Keyword(s):  
Cardiac Dysfunction ◽  
Renin Angiotensin System ◽  
High Oxygen ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Oxygen Exposure

Exposure chamber for animals at changed atmospheric conditions

1963 ◽  
Vol 18 (5) ◽  
pp. 1035-1037
Author(s):  
P. Gans
Keyword(s):  
Carbon Dioxide ◽  
High Oxygen ◽  
Continuous Treatment ◽  
Exposure Chamber ◽  
Atmospheric Conditions ◽  
High Carbon ◽  
Oxygen Exposure ◽  
Oxygen Percentage ◽  
Animal Exposure ◽  
High Carbon Dioxide

An airtight exposure chamber is described in which mice can be kept continuously in an atmosphere with a high carbon dioxide percentage, or with a low or high oxygen percentage. Advantages of the apparatus described are the absence of moving parts inside the chamber and, in the experiments with a low or high percentage of oxygen, the absorption of carbon dioxide and water outside the chamber, permitting the continuous treatment of the animals. animal exposure chamber; carbon dioxide exposure; oxygen exposure Submitted on January 4, 1963

Abstract 046: Cardiac Mitochondria are Impaired After Transient Neonatal High Oxygen Exposure in a Rat Model of Prematurity-Related Condition

Hypertension ◽  
2018 ◽  
Vol 72 (Suppl_1) ◽  
Author(s):  
Daniela Ravizzoni Dartora ◽  
Ying He ◽  
Muhammad Oneeb Rehman Mian ◽  
Alyson Deprez ◽  
Camille Girard-Bock ◽  
...  
Keyword(s):  
Rat Model ◽  
High Oxygen ◽  
Cardiac Mitochondria ◽  
Related Condition ◽  
Oxygen Exposure

scholarly journals Effect of High Oxygen Tension on Potassium Retentivity and Colony Formation of Bakers' Yeast

1962 ◽  
Vol 45 (6) ◽  
pp. 1019-1030 ◽  
Author(s):  
B. Stuart ◽  
R. Gerschman ◽  
J. N. Stannard
Keyword(s):  
Oxygen Tension ◽  
Ultraviolet Irradiation ◽  
Colony Formation ◽  
High Oxygen ◽  
Yeast Cells ◽  
Distilled Water ◽  
X Ray ◽  
Oxygen Exposure ◽  
Ray Effects ◽  
Potassium Leakage

The ability of yeast cells to retain potassium and to form colonies was studied after exposure to pressures ranging from 2 to 143 atmospheres of oxygen. The investigations allow comparison of these responses with those found after x-ray exposure. Exposure to 2 to 8 atmospheres of oxygen for 2, 20, and 40 hours showed decreased potassium leakage as measured by an elution technique. Further experiments using 0.5 to 22 hour exposures to 10 to 143 atmospheres of oxygen showed decreased potassium leakage when glucose was present in the test media, but increased leakage (as did x-ray effects) in the absence of substrate. There was increased potassium leakage into the suspending media (distilled water) during oxygen exposure but this usually did not affect the leakage rates measured subsequently. Marked inability to form colonies was observed after 20 hour exposures to 100 atmospheres of oxygen, with a much smaller response at lower pressures. Increased oxygen concentrations, not pressure, evidently caused these effects, since comparable pressures of nitrogen produced almost no change. The ratio of potassium leakage to survival sensitivity was found to be approximately unity when comparing exposures causing 50 per cent damage. This is quite different from that seen with x-ray or ultraviolet irradiation.

Sensitivity of Paramecium Caudatum to High Oxygen Tensions and Its Modification by Cobalt and Manganese Ions

1958 ◽  
Vol 192 (3) ◽  
pp. 572-576 ◽  
Author(s):  
Rebeca Gerschman ◽  
Daniel L. Gilbert ◽  
Justin N. Frost
Keyword(s):  
Morphological Changes ◽  
High Oxygen ◽  
Paramecium Caudatum ◽  
Manganese Ions ◽  
Survival Times ◽  
Hanging Drop ◽  
Oxygen Tensions

Paramecia were put in a hanging drop in a special chamber in which they could be observed under the microscope while they were exposed to different pressures of oxygen. Characteristic morphological changes were recorded photographically and were found to be very similar to changes induced by radiation. Survival times decreased from 8.05 hours at 2 atm. to 0.87 hours at 20 atm. of pO2. Treatment with cobalt (II) chloride and manganese (II) chloride (m/200,000) increased the survival times at 9 atm. and decreased them at 2 atm. pO2.

scholarly journals Vascular changes on fluorescein angiography of premature infants with low risk of retinopathy of prematurity after high oxygen exposure

2017 ◽  
Vol 3 (1) ◽  
Author(s):  
Maria Ana Martinez-Castellanos ◽  
Raul Velez-Montoya ◽  
Kenneth Price ◽  
Andree Henaine-Berra ◽  
Gerardo García-Aguirre ◽  
...  
Keyword(s):  
Fluorescein Angiography ◽  
Premature Infants ◽  
Retinopathy Of Prematurity ◽  
Low Risk ◽  
High Oxygen ◽  
Vascular Changes ◽  
Oxygen Exposure ◽  
Risk Of Retinopathy

scholarly journals Nitric Oxide Increases the Survival of Rats with a High Oxygen Exposure

1998 ◽  
Vol 43 (6) ◽  
pp. 727-732 ◽  
Author(s):  
Leif D Nelin ◽  
Stephen E Welty ◽  
James F Morrisey ◽  
Christine Gotuaco ◽  
Christopher A Dawson
Keyword(s):  
Nitric Oxide ◽  
High Oxygen ◽  
Oxygen Exposure

scholarly journals EXPERIMENTAL RATIONALE OF THE USE OF CELL THERAPY FOR THE TREATMENT OF GLAUCOMA OPTICAL NEUROPATHY

2020 ◽  
Vol 2 ◽  
pp. 40-46
Author(s):  
Sergiy Rykov ◽  
Oksana Petrenko ◽  
Antonina Yakovets ◽  
Dmytro Zubov ◽  
Roman Vasyliev
Keyword(s):  
Cell Therapy ◽  
Morphological Changes ◽  
Glaucomatous Optic Neuropathy ◽  
Retinal Layer ◽  
Histomorphometric Analysis ◽  
Delivery Methods ◽  
Neural Crest Stem Cells ◽  
Retinal Layers ◽  
Retinal Structure ◽  
Positive Effect

Development of new effective treatments for glaucomatous optic neuropathy is one of the most acute aspects of modern ophthalmology. The aim of the work is to investigate the effectiveness of cell therapy with postnatal multipotent neural crest stem cells (NCSCs) using different cell delivery methods in a model of adrenaline-induced glaucoma. Materials and methods. Glaucoma was induced in Wistar rats by intraperitoneal injections of 10 μg to 15 μg/100 g body weight of 0.18 % adrenaline hydrotartrate. NCSCs were delivered intravenously (5 million cells), retrobulbarly (0.5 million cells) or parabulbarly (0.5 million cells). Histomorphometric analysis of the retina was performed on stained haematoxylin-eosin sections with a thickness of 5 μm one month after the delivery of NCSCs. Results. NCSCs transplantation by all modes of delivery caused positive morphological changes to varying degrees. Intravenous administration induced a decrease in edema in all retinal layers and a slight restoration of the cytoarchitectonics of the retinal layers. The parabulbar administration of NCSCs led to a decrease in edema and the restoration of the cytoarchitectonics of the layers, most pronouncedly the ganglion cell layer and the inner retinal layer. After the retrobulbar administration of NCSCs, the reduction in edema and restoration of the cytoarchitectonics of the layers were the most pronounced. Conclusions. According to the results of the study, the positive effect of NCSCs transplantation in an experimental model of glaucoma was the most pronounced following the retrobulbar injection of cells. Further investigations of the mechanisms of the effect of transplanted NCSCs on retinal structure restoration are needed.

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