scholarly journals The combined effect of high-intensity intermittent training and vitamin D supplementation on glycemic control in overweight and obese adults

2018 ◽  
Vol 6 (9) ◽  
pp. e13684 ◽  
Author(s):  
Hannah Margaret Lithgow ◽  
Geraint Florida-James ◽  
Melanie Leggate
2021 ◽  
Vol 8 ◽  
Author(s):  
Mohammad Ali ◽  
Zakir Uddin ◽  
Ahmed Hossain

Background: The prevalence of musculoskeletal disorders (MSD) and vitamin D insufficiency is high. Past research indicating vitamin D supplementation and physiotherapy are useful for the treatment of MSDs. However, to the best of our knowledge, the combined benefits of vitamin D and physiotherapy are not yet evaluated in MSD. We hypothesized that combined intervention of vitamin D supplementation and physiotherapy would be more effective in relieving the pain of MSD compared to only physiotherapy intervention.Objective: This study aimed to examine whether combined effect of vitamin D supplementation and physiotherapy was better than physiotherapy alone in reducing pain-related outcomes (e.g., pain severity, affective interference, and physical interference) in patients with MSD.Methods: A quasi-clinical experiment was conducted between May 2020 and April 2021. Vitamin D level in the blood was measured at the start of the study. Patients with vitamin D levels <20 ng/mL were assigned to the combined physiotherapy and vitamin D group. The physiotherapy group consisted of the patients with vitamin D levels more than 20 ng/mL. The Brief Pain Inventory scale was utilized to measure pain at baseline and after 12 weeks of interventions. We used the paired t-tests for unadjusted analysis. Further, a linear regression model was used to identify the combined effect of physiotherapy and vitamin D on reducing pain scores after adjusting potential confounders.Results: Combined intervention of vitamin D and physiotherapy showed significantly better results than only physiotherapy intervention in the reduction of three pain-related outcomes (p < 0.001). The multivariable analysis indicated that the combination of physiotherapy and vitamin D treatment reduced pain score by 1.126 (slope = −1.126, p = 0.035) compared to physiotherapy alone.Conclusion: Combined intervention (vitamin D with physiotherapy) had a better pain-relieving effect than physiotherapy alone. To confirm these findings, more research is needed with randomized control trials.Clinical Trial Registration: [http://ctri.nic.in/Clinicaltrials/advancesearchmain.php], identifier [CTRI/2020/04/024845].


2016 ◽  
Vol 20 (2) ◽  
pp. 189 ◽  
Author(s):  
AnthonyChinedu Anyanwu ◽  
OlufemiAdetola Fasanmade ◽  
IfedayoAdetola Odeniyi ◽  
Sandra Iwuala ◽  
HerbertBabatunde Coker ◽  
...  

Author(s):  
Nur Syimah Izzah Abdullah Thani ◽  
Roslaili Khairudin ◽  
Jacqueline J Ho ◽  
Nor Asiah Muhamad ◽  
Hirman Ismail

2020 ◽  
Author(s):  
Xiaomin Sun ◽  
Sirui Zhou ◽  
Mengyue Dong ◽  
Wenjuan Xiao ◽  
Xin He ◽  
...  

Abstract Aims This study aimed to examine the effect of a 12-week vitamin D supplementation and exercise training alone and in combination on glycemic control and bone health in Chinese type 2 diabetes patients.MethodsSixty-one type 2 diabetes patients (age, 33–65 years; 72.0% men) with non-insulin dependence were randomized into the 12-week vitamin D group (1000 IU/day), exercise group (60%–80% of maximal heart rate, 1 h/time, 2–3 times/week), vitamin D combined with exercise group, and control group. A 75-g oral glucose tolerance test was used to estimate glycemic control. Dual X-ray absorptiometry was used to examine bone health (bone mass content and bone mass density) and body fat percentage (%).Results During the 75-g oral glucose tolerance test, lower glucose and higher insulin levels were found in the vitamin D combined with exercise group, vitamin D group, and exercise group after intervention than before intervention, although the differences were not statistically significant. A significant exercise and vitamin D interaction for the insulinogenic index (P = 0.032) and a borderline interaction for the glucose disposition index (P = 0.051) were observed, while no further independent effect was observed. Compared with non-vitamin D supplementation, vitamin D supplementation significantly alleviated the loss of total bone mass content (95% CI: -29.9–19.4 vs. -74.9–-24.7), trunk bone mass content (95% CI: -24.1–19.5 vs. -56.1–-11.7), and spine bone mass density (95% CI: -0.03–0.03 vs. -0.07–-0.01).ConclusionsThe findings suggest that 12-week combined vitamin D and exercise intervention has a potentially positive effect on glycemic control, and vitamin D supplementation plays an important role in the prevention of bone loss, which was identified in the exercise alone group. Further studies are needed to elucidate the long-term effect of combined vitamin D and exercise intervention in type 2 diabetes patients.The study was registered in the Chinese Clinical Trial System (No. ChiCTR1800015383).


Author(s):  
Marlene T Chakhtoura ◽  
Nancy F Nakhoul ◽  
Elie A Akl ◽  
Bassem Y Safadi ◽  
Christos S Mantzoros ◽  
...  

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