scholarly journals Local transmural action potential gradients are absent in the isolated, intact dog heart but present in the corresponding coronary-perfused wedge

2017 ◽  
Vol 5 (10) ◽  
pp. e13251 ◽  
Author(s):  
Bastiaan J. Boukens ◽  
Veronique M. F. Meijborg ◽  
Charly N. Belterman ◽  
Tobias Opthof ◽  
Michiel J. Janse ◽  
...  
Keyword(s):  
Action Potential ◽  
Dog Heart ◽  
Potential Gradients

scholarly journals Is action potential duration of the intact dog heart related to contractility or stimulus rate?

1982 ◽  
Vol 331 (1) ◽  
pp. 499-510 ◽  
Author(s):  
Angela J. Drake ◽  
Mark I. M. Noble ◽  
Vincent Schouten ◽  
Anthony Seed ◽  
Henk E. D. J. Ter Keurs ◽  
...  
Keyword(s):  
Action Potential ◽  
Action Potential Duration ◽  
Dog Heart ◽  
Stimulus Rate

YIA3 Regional Action Potential Gradients in the Murine Left Atrium

Heart ◽  
2015 ◽  
Vol 101 (Suppl 4) ◽  
pp. A123.1-A123
Author(s):  
Andrew Holmes ◽  
Ting-Yue Yu ◽  
Stefan Kuhlman ◽  
Fahima Syeda ◽  
Larissa Fabritz ◽  
...  
Keyword(s):  
Action Potential ◽  
Left Atrium ◽  
Potential Gradients

Acute effects of quinidine on K exchange and distribution in the dog ventricle

1960 ◽  
Vol 199 (1) ◽  
pp. 151-156 ◽  
Author(s):  
Hadley L. Conn ◽  
John C. Wood
Keyword(s):  
Oxygen Consumption ◽  
Gas Exchange ◽  
Action Potential ◽  
Respiratory Quotient ◽  
Resting Potential ◽  
Acute Effects ◽  
Dog Heart ◽  
Potassium Influx ◽  
Potassium Exchange ◽  
Potassium Metabolism

Some of the effects of quinidine on potassium metabolism and gas exchange were studied in the isolated perfused dog heart. The major changes found were an increase in cell K and transcellular K exchange, and a decrease in oxygen consumption and respiratory quotient. The increase in K exchange was apparently due to an increased resting potential potassium exchange with little or no alteration in exchange during the action potential. The accumulation of cell K seemed to be dependent mainly on an initial resting phase increase in potassium influx.

scholarly journals Cardiac action potential duration and contractility in the intact dog heart.

1983 ◽  
Vol 345 (1) ◽  
pp. 75-85 ◽  
Author(s):  
A J Drake-Holland ◽  
M I Noble ◽  
M Pieterse ◽  
V J Schouten ◽  
W A Seed ◽  
...  
Keyword(s):  
Action Potential ◽  
Action Potential Duration ◽  
Cardiac Action Potential ◽  
Dog Heart ◽  
Cardiac Action ◽  
Cardiac Action Potential Duration

Summating Potential and Action Potential Gradients on and in the Vicinity of the round Window in Guinea Pig

1997 ◽  
Vol 106 (2) ◽  
pp. 139-144 ◽  
Author(s):  
Mohamed Badr-El-Dine ◽  
George M. Gerken ◽  
William L. Meyerhoff
Keyword(s):  
Guinea Pig ◽  
Action Potential ◽  
Guinea Pigs ◽  
Round Window ◽  
Free Field ◽  
Tone Burst ◽  
Equal Area ◽  
Spatial Gradients ◽  
Summating Potential ◽  
Potential Gradients

The purpose of this study was to determine the spatial gradients of summating potential (SP) amplitudes, action potential (AP) amplitudes, and SP/AP ratios for recording loci on the round window (RW) membrane and in its vicinity. Sixteen guinea pigs were tested by means of free-field click and tone burst (2.0 kHz) stimuli. Seven recording regions were specified: five equal-area regions on the RW membrane and two basal promontory regions. Statistically significant differences were found between the promontory regions and the RW membrane regions for the SP, AP, and SP/AP obtained with click stimuli, and for the SP and AP obtained with tone burst stimuli. The SP/AP ratio for tone burst stimuli did not differ significantly across the seven regions. The RW membrane was found to be isoelectric, but there were marked spatial gradients on the basal promontory. These results are of consequence for the interpretation of transtympanic electrocochleography recordings.

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