Cystic degeneration of uterine leiomyoma during ulipristal acetate treatment

2016 ◽  
2017 ◽  
Vol 43 (1) ◽  
pp. 121-123 ◽  
Author(s):  
Z. Hrgovic ◽  
D. Habek ◽  
J. Cerkez Habek ◽  
I. Hrgovic ◽  
S. Jerkovic Gulin ◽  
...  

2007 ◽  
Vol 46 (4) ◽  
pp. 431-434 ◽  
Author(s):  
Mei-Shan Jao ◽  
Kuan-Gen Huang ◽  
Shih-Ming Jung ◽  
Lih-Lian Hwang

2022 ◽  
Vol 13 (1) ◽  
pp. 129-135
Author(s):  
Lipika Ghosh ◽  
Abhijit Rakshit ◽  
Madhumita De

Background: Fibroid or uterine leiomyoma is the most common benign tumor of the uterus in the reproductive age group and found in one out of every four women. They are symptomatic in 50% of women, with the peak incidence occurring among women in their 30s or 40s. Fibroid can cause a variety of symptoms which include menstrual disturbances commonly menorrhagia and dysmenorrhea. It is a common indication of hysterectomy in Indians. An effective medical treatment option may reduce hysterectomy-associated morbidity and mortality. This study is undertaken to evaluate the efficacy and safety of medical management of myoma and contribution in the reduction of myoma size comparing the two drugs ulipristal and mifepristone. Aims and Objectives: The study was conducted to compare reduction of menorrhagia (By pictorial blood loss assessment chart score), reduction of fibroid size (using transvaginal ultrasonography), and improvement of hemoglobin (Hb) level. We are also evaluating safety or side effects using these drugs. Materials and Methods: The study includes 210 patients who are divided into two groups. Group A includes 105 patients who are treated with tablet Ulipristal Acetate 5 mg daily for 3 months and Group B includes 105 patients who are treated with tablet mifepristone 25 mg daily for 3 months. Results: Ulipristal and mifepristone both are effective in reduction of menorrhagia and improvement of Hb levels, but Ulipristal is more effective in reduction of size of uterine myoma than mifepristone after 3 months of treatment. Conclusion: Multicentric study over a larger population is required to reach a valid conclusion.


2017 ◽  
Vol 0 (36) ◽  
pp. 76-81
Author(s):  
Р. А. Сафонов ◽  
И. Н. Сафонова

2020 ◽  
Vol 87 (2) ◽  
pp. 80-86 ◽  
Author(s):  
Ayumi Yaguchi ◽  
Kenji Ban ◽  
Yuichiro Koshida ◽  
Yusuke Fujikami ◽  
Eri Ogura ◽  
...  

2019 ◽  
Vol 112 (6) ◽  
pp. 1150-1159 ◽  
Author(s):  
Barbara Del Bello ◽  
Paola Marcolongo ◽  
Pasquapina Ciarmela ◽  
Flavia Sorbi ◽  
Felice Petraglia ◽  
...  

2018 ◽  
Vol 29 (3) ◽  
Author(s):  
Tae-Hyung Kim ◽  
Jae-Weon Kim ◽  
Sang Youn Kim ◽  
Seung Hyup Kim ◽  
Jeong Yeon Cho

2018 ◽  
Vol 7 (4) ◽  
pp. 185-186
Author(s):  
Rupa Paneru ◽  
Meena Thapa

Background: Leiomyomas are benign smooth muscle neoplasm that typically occurs from the myometrium. Most of the women with uterine leiomyoma remain asymptomatic. Various degeneration including hyaline, cystic, myxoid and red degeneration and dystrophic calcification occur in leiomyoma, among them myxoid degeneration occurs rarely. Here is a case report of 40 years with one living child and two abortions who came with complaints of feeling of heaviness and pain at lower abdomen for six months, palpable lower abdominal mass for four months and difficulty in passing urine since 15 days. Multiple fibroids with cystic degeneration were suspected in Computed Tomography scan report. The patient underwent Total Abdominal Hysterectomy with Bilateral Salphingectomy. On cut section there was a cystic area on the body of uterus containing 1. 1 liter of straw coloured fluid. Final histopathological findings concluded multiple leiomyoma with myxoid degeneration.


Author(s):  
Sonali Kalyan ◽  
Sonam Sharma

Uterine leiomyomas are one of the most common entities encountered in routine gynaecological practice; however, the giant uterine myomas are very rare and can often create a diagnostic dilemma and therapeutic challenge owing to their size, non-specific clinical presentation and degenerations. Here, in this article we review the literature on giant uterine leiomyomas and report one such case in a 38-year-old woman who presented with the complaints of vague abdominal lump, enlargement of abdomen, dysmenorrhea, lower abdominal and pelvic pain since last 2 years and a 6-month history of increased frequency of micturation. Physical examination and radiological investigations suggested a giant abdominopelvic mass, probably a uterine or an ovarian malignancy. An exploratory laparotomy was performed followed by total hysterectomy. Grossly, the specimen was a 15.2 kg uterine leiomyoma measuring 18x18x13 cm in size. Histologically, the benign leiomyoma showed cystic degeneration. The patient’s post-operative and follow-up period was uneventful.


2016 ◽  
Vol 10 ◽  
pp. 1-3 ◽  
Author(s):  
Katrin Arnolds ◽  
Emily Senderey ◽  
Michael L. Sprague ◽  
Rodolfo Blandon ◽  
Diane L. Carlson ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document