scholarly journals The Family and Biology: Challenges of the Artificial Reproductive Technologies.

2014 ◽  
Vol 9 (1(15)) ◽  
pp. 149-165
Author(s):  
John M. Grondelski
Keyword(s):  
Reproductive Technologies ◽  
Egg Donation ◽  
Documentary Films ◽  
Sperm Donation ◽  
Surrogate Motherhood ◽  
Vitro Fertilization ◽  
Social Trends ◽  
The Family ◽  
Biological Foundation

Artificial reproductive technologies such as sperm and egg donation, in vitro fertilization, and surrogate motherhood all in principle separate the family from its biological foundation. These technologies enable and promote contemporary social trends that disconnect the family from its biological basis and claim that a family is constituted by an act of will, irrespective of biology. The article discusses three recent documentary films made by American Center for Bioethics and Culture, which consist of interviews with children born from sperm donation and women involved in egg donation and surrogate motherhood, to identify how the biological understanding of parenthood is undermined by these technologies and the ethical and anthropological consequences that follow. The author concludes that these technologies are also in principle available to single persons and to homosexuals to enable them to "have" children. He warns that potential and real deleterious effects of such behavior will be satisfying adults' whims by children.

scholarly journals 輔助生殖技術應用的儒家倫理解讀

2011 ◽  
Vol 9 (1) ◽  
pp. 23-37
Author(s):  
Xiangjin KONG ◽  
Mingjie ZHAO
Keyword(s):  
Normal Family ◽  
Family Values ◽  
National Politics ◽  
Surrogate Motherhood ◽  
Vitro Fertilization ◽  
Ethical Implications ◽  
Digital Commons ◽  
The Family ◽  
Confucian Moral

LANGUAGE NOTE | Document text in Chinese; abstract also in English.因人類輔助生殖技術應用引發的生命倫理問題，已成為現代生命倫理學界研究的重點領域。隨著輔助生殖技術的進步與發展，所產生的生命倫理問題也愈來愈複雜，現代生命倫理學各學派對這些倫理問題的爭論也愈來愈激烈。本文以儒家家庭倫理觀對這些倫理問題進行解析，以期為解決這些倫理問題爭論提供一個新的視角。Assisted reproductive technology (ART) has provided both opportunities and crises for people to achieve pregnancy and reproduction by artificial or partially artificial means. As Chinese people have been shaped by Confucian family values, they are committed to pursuing the continuity, integrity, and prosperity of the family. Applying ART is not unethical in principle. However, different types of ART carry different ethical implications and should be defined clearly according to the Confucian moral perspective.Confucian ethics is committed to maintaining the continuity of the family. For infertile couples, both artificial insemination (AI) and in vitro fertilization (IVF) can be beneficial and justifiable, as long as the sperms and eggs involved are only from the husband and wife. However, according to the Confucian understanding of the integrity of the family, an AI or IVF by donor, rather than the husband, would destroy the blood-tie of the family, and is therefore ethically unjustifiable. In addition, Confucianism appreciates that a normal family must have both a husband and a wife, and that a child ought to be born in a normal family with both a father and a mother. Accordingly, it is ethically problematic for single men or women to use ART to conceive a child. Moreover, it is very difficult for Confucians to defend the practice of surrogate motherhood because the intrusion of another woman into a family would significantly threaten the peace and integrity of the family and be harmful to the development of the child.This paper does not intend to argue that all traditional Confucian ethical views are absolutely right and should never be changed. It does, however, argue that Confucian moral values and commitments should be taken seriously. These values and commitments are still vibrant in Chinese people’s lives, although they have not been promoted systematically in national politics. As they are embedded in the Chinese ways of life, Chinese bioethicists should carefully examine these views and provide relevant arguments for their preferred programs and solutions regarding the application of reproductive technologies.DOWNLOAD HISTORY | This article has been downloaded 169 times in Digital Commons before migrating into this platform.

On Teaching Biopolicy and Values in Selected Reproductive Technologies: Abortion, In Vitro Fertilization, and Surrogate Motherhood

1986 ◽  
Vol 5 (1) ◽  
pp. 75-82 ◽  
Author(s):  
Lois B. Moreland
Keyword(s):  
Course Design ◽  
Reproductive Technologies ◽  
Course Development ◽  
Computer Search ◽  
Visual Aids ◽  
Surrogate Motherhood ◽  
Faculty Preparation ◽  
Vitro Fertilization ◽  
Reading Materials

This article is divided into three parts: “Faculty Preparation: Immersion in the Literature,” “Conceptualizing and Organizing the Course,” and “Course Design.” The first part is addressed particularly to readers without access to a computer search of the literature. It suggests resource materials for each of the technologies. It also speaks to the meanings of and approaches which may be used to study biopolitics. Biopolicy is the approach used in the course.The second part addresses the problem of finding a unifying concept which would bring cohesion to the multiple and diverse materials and issues. It also includes the statement of purpose and course objectives. It is here that the development of identifying and demonstrating the nexus between the reproductive technologies and public policy begins. It also discusses methodologies used in the course.The third part lists the activities that served as a guide in designing the course and cites remaining caveats in course development. The paper concludes with statements about required reading materials, review materials, audio-visual aids, and a broad outline of the course.

scholarly journals Evolution of surrogate motherhood: legal aspect

2020 ◽  
pp. 41-46
Author(s):  
Yu.M. Yakushchenko
Keyword(s):  
Assisted Reproductive Technologies ◽  
Legal Aspect ◽  
Reproductive Technologies ◽  
Modern Method ◽  
Legal Regulation ◽  
Ancient Egypt ◽  
Surrogate Motherhood ◽  
Vitro Fertilization ◽  
History Of

The article deals with the study of the history of surrogate motherhood in the world, since the study of the origin of surrogacy and the history of its legal regulation will allow gaining greater insight into the legal nature of this phenomenon. The main periods of development of legislation in the field of surrogacy were analyzed and characterized, and the main problems were identified, as well as further ways of improvement. It is stated that this phenomenon is not new in the history of mankind. It was used in Ancient Egypt, Ancient Greece and Mesopotamia, and the first mentions can be found in the Old Testament. Attention is drawn to the fact that prior to the discovery of the in vitro fertilization method, there was only the traditional form of surrogate motherhood, which in most cases was governed by the rules of morality and customs prevailing at that time in a particular society. It is emphasized that the first references to the legal consolidation of this practice can be found in the Code of Hammurabi. It is stated that surrogacy as a modern method of assisted reproductive technologies has been used since 1985. It is argued that the active development of legislation in this field began after this year. The court cases were considered, which become decisive for the further formation of legislation on surrogacy. The article lists the main legal acts that regulated surrogate motherhood in Ukraine, those that are in force, and those that are invalid. It is concluded that gestational surrogacy as a method of assisted reproductive technology is becoming increasingly popular method for the treatment of infertility, and its legal regulation needs to be improved, especially at the level of international law.

The experience of holding the cycles of assisted reproductive technology with defrost, a biopsy, genetic study and refreezing of embryos in patients with multiple unsuccessful implantations

2016 ◽  
pp. 166-170
Author(s):  
Y.V. Masliy ◽  
◽  
I.O. Sudoma ◽  
P.S. Mazur ◽  
D.A. Mykytenko ◽  
...  
Keyword(s):  
Chromosomal Rearrangements ◽  
Genetic Diagnosis ◽  
Morphological Characteristics ◽  
Implantation Rate ◽  
Ovarian Response ◽  
Reproductive Technologies ◽  
Comparative Genome Hybridization ◽  
Comparative Genome ◽  
Vitro Fertilization

The objective: to study the possibility of using frozen blastocysts for biopsy and genetic testing and performance measurement transfer euploeded 5–7-day-old embryos after thawing, biopsies, refreezing and thawing in patients with unsuccessful implantation. Patients and methods. The object of the study was the group of patients with repeated failure of implantation (4) in programs of auxiliary reproductive technologies (ART), subject to transfer to the uterus in total (i.e. in all the programs) for at least 6 good quality embryos based on morphological characteristics). All women had sufficient ovarian reserve. The patient was treated for infertility within the ART programs of the clinic of reproductive medicine "Nadiya" in the period from 2006 to 2016. The sample included couples who were not carriers of chromosomal rearrangements, without anomalies of the uterus (congenital and acquired: a doubling of the uterus, one-horned uterus, intrauterine membrane, synechia, submucous myoma of the uterus). All women had a positive ovarian response to controlled stimulation with gonadotropins (at least 7 oocytes) and a sufficient number of cryopreserved embryos. The first group (G1) included 64 women who trophectodermal a biopsy was performed on fresh blastocysts (in a loop controlled ovarian hyperstimulation). The second group (G2) were included 31 women who underwent thawing previously cryopreserved blastocysts trophectodermal re-biopsy and vitrification of blastocysts. Results. It was found that the performance of transfers euploid embryos that were vitrified, bioptrone and revitriphted, a little lower than those that were bioptrone fresh and vitrified only once. At the same time computationa genetic diagnosis previously vitrified blastocysts using comparative genome hybridization in patients with recurrent failed implantation allows to obtain a reasonable pregnancy rate (58%), implantation rate (33.3 %) and the birth of living children (45.1 %). Conclusion. Reprising biopropane embryos does not cause significant destructive impact and allows you to achieve pregnancy and birth of the alive child. Key words: in vitro fertilization, reusable unsuccessful implantation, a method of comparative genome hybridization, refreezing.

Thickness of endometrium: predictor of the effectiveness of IVF/ICSI programs (literature review)

GYNECOLOGY ◽  
2018 ◽  
Vol 20 (1) ◽  
pp. 113-116
Author(s):  
L A Bagdasaryan ◽  
I E Korneyeva
Keyword(s):  
Assisted Reproductive Technologies ◽  
Endometrial Thickness ◽  
Molecular Genetic ◽  
Uterine Cavity ◽  
Reproductive Technologies ◽  
Genetic Characteristics ◽  
Vitro Fertilization ◽  
Need To Evaluate ◽  
The Relationship

The aim of the study is to systematically analyze the data available in the modern literature on the relationship between endometrial thickness and the frequency of pregnancy in the program of assisted reproductive technologies (ART). Materials and methods. The review includes data from foreign and domestic articles found in PubMed on this topic. Results. The article presents data on the relationship between the thickness of the endometrium and the frequency of pregnancy in ART programs. The greatest number of studies is devoted to the evaluation of the relationship between the thickness of the endometrium and the frequency of pregnancy on the day of the ovulation trigger. Data are presented on the existence of a correlation between the thickness of the endometrium measured on the day of the ovulation trigger and the frequency of clinical pregnancy, as well as data on the need to evaluate the structure of the endometrium and the state of subendometric blood flow. The importance of multilayered (three-layered) endometrium as a prognostic marker of success in in vitro fertilization/intracytoplasmic sperm injection programs in the ovum is emphasized. The conclusion. The thickness of the endometrium can not be used as an argument for canceling the cycle or abolishing embryo transfer to the uterine cavity. Further studies in this direction are needed with a study of the morphological and molecular genetic characteristics of the endometrium, which in the future will allow us to evaluate the relationship between the thickness of the endometrium and the probability of pregnancy.

Legal restrictions on pre-implantation genetic diagnostics in the framework of in vitro fertilization procedure: foreign experience and Russian perspective

2019 ◽  
Author(s):  
N.A. Altinnik , S.S. Zenin , V.V. Komarova et all
Keyword(s):  
In Vitro Fertilization ◽  
Assisted Reproductive Technologies ◽  
Genetic Diseases ◽  
Genetic Diagnosis ◽  
Reproductive Technologies ◽  
Legal Regulation ◽  
Genetic Diagnostics ◽  
Vitro Fertilization ◽  
Medical Indications

The article discusses the factors that determine the content of the legal limitations of pre-implantation genetic diagnosis in the framework of the in vitro fertilization procedure, taking into account international experience and modern domestic regulatory legal regulation of the field of assisted reproductive technologies. The authors substantiates the conclusion that it is necessary to legislate a list of medical indications for preimplantation genetic diagnosis, as well as the categories of hereditary or other genetic diseases diagnosed in the framework of this procedure.

scholarly journals Prevalence of pathogenic copy number variants among children conceived by donor oocyte

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sandra Monfort ◽  
Carmen Orellana ◽  
Silvestre Oltra ◽  
Mónica Rosello ◽  
Alfonso Caro-Llopis ◽  
...  
Keyword(s):  
In Vitro Fertilization ◽  
Copy Number ◽  
Assisted Reproductive Technologies ◽  
Copy Number Variants ◽  
Reproductive Technologies ◽  
Significant Excess ◽  
Vitro Fertilization ◽  
Donor Oocyte ◽  
Increased Risk

AbstractDevelopment of assisted reproductive technologies to address infertility has favored the birth of many children in the last years. The majority of children born with these treatments are healthy, but some concerns remain on the safety of these medical procedures. We have retrospectively analyzed both the fertilization method and the microarray results in all those children born between 2010 and 2019 with multiple congenital anomalies, developmental delay and/or autistic spectrum disorder (n = 486) referred for array study in our center. This analysis showed a significant excess of pathogenic copy number variants among those patients conceived after in vitro fertilization with donor oocyte with respect to those patients conceived by natural fertilization (p = 0.0001). On the other hand, no significant excess of pathogenic copy number variants was observed among patients born by autologous oocyte in vitro fertilization. Further studies are necessary to confirm these results and in order to identify the factors that may contribute to an increased risk of genomic rearrangements, as well as consider the screening for genomic alterations after oocyte donation in prenatal diagnosis.

scholarly journals Sperm Selection Procedures for Optimizing the Outcome of ICSI in Patients with NOA

2021 ◽  
Vol 10 (12) ◽  
pp. 2687
Author(s):  
Kaan Aydos ◽  
Oya Sena Aydos
Keyword(s):  
In Vitro Selection ◽  
Assisted Reproductive Technologies ◽  
Reproductive Technologies ◽  
Testicular Sperm Extraction ◽  
Obstructive Azoospermia ◽  
Sperm Retrieval ◽  
Vitro Fertilization ◽  
Great Hope ◽  
Future Fertility

Retrieving spermatozoa from the testicles has been a great hope for patients with non-obstructive azoospermia (NOA), but relevant methods have not yet been developed to the level necessary to provide resolutions for all cases of NOA. Although performing testicular sperm extraction under microscopic magnification has increased sperm retrieval rates, in vitro selection and processing of quality sperm plays an essential role in the success of in vitro fertilization. Moreover, sperm cryopreservation is widely used in assisted reproductive technologies, whether for therapeutic purposes or for future fertility preservation. In recent years, there have been new developments using advanced technologies to freeze and preserve even very small numbers of sperm for which conventional techniques are inadequate. The present review provides an up-to-date summary of current strategies for maximizing sperm recovery from surgically obtained testicular samples and, as an extension, optimization of in vitro sperm processing techniques in the management of NOA.

Peculiarities of pregnancy and delivery course in women after the application of assisted reproductive technologies against obesity (Based on the retrospective analysis)

2018 ◽  
pp. 122-126
Author(s):  
I.A. Zhabchenko ◽  
◽  
O.R. Sudmak ◽  
Keyword(s):  
In Vitro Fertilization ◽  
Pregnant Women ◽  
Retrospective Analysis ◽  
Perinatal Outcomes ◽  
Reproductive Technologies ◽  
Ischemic Lesion ◽  
Vitro Fertilization ◽  
Pregnancy And Delivery

The objective: to study the structure and frequency of complications of pregnancy, deliveries and perinatal outcomes in three groups of women: women with infertility and obesity, treated by application of in vitro fertilization (hereinafter IVF), pregnant women after IVF application with normal body weight, and pregnant women on the background of obesity which did not have an infertility in past history. Materials and methods. A retrospective analysis of 221 case histories of pregnancies and labors in women who were treated and gave birth in the Pregnancy and delivery pathology Department of SI «Institute of Pediatrics, Obstetrics and Gynecology named after Acad. O. M. Lukyanova of NAMS of Ukraine» for 2012 – 2016 years was carried out. Results. The overwhelming majority of pregnant women after IVF on the background of obesity are primaparas, who have a complicated obstetric history, hormonal changes in the form of progesterone deficiency predominantly and chronic inflammatory processes. Pregnancy with a combination of infertility, treated by the means of IVF application, and obesity, in most cases is accompanied by a long-term threat of termination of pregnancy (48.8%), threatening preterm deliveries (56%), placental dysfunction (41.5%), premature rupture of the amniotic membranes (41.5%), other problems during pregnancy, at the same time, every second woman (58.5%) had a combination of several complications, and required a long-term and repeated inpatient treatment (53.7%). The specific gravity of surgical delivery was 90%, and 16.2% of such deliveries were complicated by pathological blood loss. The number of preterm deliveries was 17.1%, with perinatal losses up to 11.3‰. Among full-term newborns 21.3% of newborns had malnutrition of the I degree and 17% of them had hypoxic-ischemic lesion of CNS. Conclusion. The course of pregnancy, delivery and the postpartum period in the studied contingent of women has a significant frequency of complications, mainly the coinciding ones, which affects on the consequences of perinatal outcomes and requires further study of this problem and the development of differentiated algorithms for antenatal observation. Key words: pregnancy, obesity, in vitro fertilization, complications, delivery, newborn.

A Baby at All Costs? Exploring the Use and Provision of Unproven Adjuvant Treatments in the Context of IVF

2021 ◽  
Author(s):  
Georgina L. Jones ◽  
Victoria Lang ◽  
Nicky Hudson
Keyword(s):  
Reproductive Technologies ◽  
Patient Survey ◽  
Fertility Treatment ◽  
Vitro Fertilization ◽  
The Past ◽  
The United Kingdom ◽  
Wide Range ◽  
National Patient ◽  
Psychosocial Perspective

AbstractThe year 2018 marked 40 years since the birth of Louise Brown, the first baby born as a result of pioneering in vitro fertilization (IVF) treatment. Since then, advances have seen a wide range of reproductive technologies emerge into clinical practice, including adjuvant treatments often referred to as IVF “add-ons.” However, these “optional extras” have faced growing criticism, especially when they have often come at additional financial cost to the patient and have little evidence supporting their efficacy to improve pregnancy or birth rates. Despite this, according to the latest national patient survey by the Human Fertilisation and Embryology Authority, three quarters of patients who had fertility treatment in the United Kingdom in the past two years had at least one type of treatment add-on highlighting the growing demand for these interventions. This article uses a psychosocial perspective to consider the motivations behind patient and clinician behavior along with the wider societal and economic factors that may be impacting upon the increase in the use of adjuvant treatments in fertility clinics more widely. It suggests the reasons fertility patients use unproven “optional extras” are complex, with interpersonal, psychological, and social factors intertwining to generate an increase in the use of IVF add-ons.

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