scholarly journals Evaluation of vitamin D Levels and QT dispersions in children with chest pain

2020 ◽  
Keyword(s):  
Vitamin D ◽  
Chest Pain ◽  
Vitamin D Levels

scholarly journals Hypovitamanosis D and non cardiac chest pain

2020 ◽  
Vol 8 (6) ◽  
pp. 2210
Author(s):  
B. V. Nagabhushana ◽  
G. Mahesh ◽  
P. S. S. Subramanyam ◽  
A. Rekha
Keyword(s):  
Vitamin D ◽  
Chest Pain ◽  
Vitamin D Deficiency ◽  
Medical Condition ◽  
Atypical Chest Pain ◽  
Vitamin D Levels ◽  
Outpatient Departments ◽  
Cardiac Illness ◽  
Artery Disease ◽  
One Year

Background: Recurrent atypical chest pain not due to cardiac illness is a very common condition in medical outpatient departments. Authors found that people consulting for atypical chest pain often have significant Vitamin D deficiency and correction of Vitamin D deficiency relieved patient symptoms. Hence authors carried out this study.Methods: Persons aged below 50 years were taken up for study. Those attending medical clinics with complaints of chest pain occurring more than two times were taken up for study. Cardiac illness was excluded by clinical examination and investigations. Those found to have low Vitamin D were taken up for study. 60,000 international units Vitamin D was administered orally weekly for 8 weeks. They were followed up twice weekly for three months and once monthly for three months.Results: Results were analyzed and charted. 120 subjects were taken up for study and duration of study was three years. Average age of the study group was 37.50 years and the average Vitamin D level was 15.75 nanogram/ml (ngm/ml). Duration of chest pain ranged from one week to one year. Most of the patients had migratory chest pain.Conclusions: As Vitamin D deficiency is a treatable medical condition it may be prudent to check Vitamin D levels in the patients presenting with recurrent atypical pain in the chest. It reduces the burden on the health care system and relieves the suffering of the patient. It may not be futile to check Vitamin D levels even in the patients with coronary artery disease who are suffering from atypical chest pain.

Abstract P325: The Prognostic Utility of Vitamin D and Its Seasonal Variation in Chest Pain Patients with Suspected Acute Coronary Syndrome Recruited from a Coastal Population in Western-Norway

Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Patrycja A Naesgaard ◽  
Volker Pönitz ◽  
Trygve Brúgger-Andersen ◽  
Hildegunn Aarsetoey ◽  
Heidi Grundt ◽  
...  
Keyword(s):  
Vitamin D ◽  
Chest Pain ◽  
Total Population ◽  
Univariate Analysis ◽  
Coronary Syndrome ◽  
Western Norway ◽  
Vitamin D Levels ◽  
Prognostic Utility ◽  
The Mean ◽  
Pain Patients

Background: Several studies have shown a correlation between low vitamin D levels and cardiovascular risk. Serum concentration of 25-hydroxy-vitamin D (25(OH)D) is an established marker of vitamin D status. The purpose of this study was to assess the prognostic utility of 25(OH)D status in 871 chest-pain patients with suspected acute coronary syndrome (ACS) from Western-Norway. Methods: Serum samples for determination of 25(OH)D were obtained at admission. Baseline data consisted of serum levels of Troponin T (TnT), high sensitive C-reactive protein, creatinine, glucose, lipids and B-type natriuretic peptide measured in EDTA plasma, as well as clinical parameters, including age, gender, previous MI, angina pectoris, previous revascularizations (percutaneous coronary intervention or coronary artery bypass graft), congestive heart failure, diabetes mellitus, smoking status, hypercholesterolemia (total cholesterol > 250 mg/dl or statin treated hypercholesterolemia), beta-blocker prior to enrolment, hypertension, body mass index and seasons (defined as November through April and May through October). The main endpoint was total mortality in the total population and in the TnT positive group (TnT > 0.01 ng/mL). Multivariate analysis was performed in 794 patients with a complete set of baseline variables. Results: The mean age was 69.6 and 39% were females. After 24 months follow-up, 136 patients had died. The mean vitamin D value was 53.8 nM (95% CI, 52.2 nM - 55.4 nM) between November 2002 and April 2003, and 50.2 nM (95%CI, 48.1 nM - 52.3 nM) between May 2003 and October 2003; p = 0.008. In the univariate analysis of all cause mortality in the total population, the hazard ratio (HR) for 25(OH)D in the highest quartile as compared to the lowest quartile was 0.63 (95% confidence interval (CI), 0.38 - 1.03), p = 0.065, and in the TnT positive patients the HR was 0.58 (95% CI, 0.33 - 1.03), p = 0.062. No difference in mortality was found between the vitamin D quartiles in the TnT negative population. The results remained statistically non-significant in the multivariate analysis. Conclusion: In an univariate analysis there was a trend towards higher mortality in the lowest quartile of vitamin D as compared to the highest quartile in our chest pain population with suspected ACS. Furthermore, there was a statistically significant seasonal difference in vitamin D levels.

Abstract #421 Association of Vitamin D Levels with the Severity of Fibrosis in NAFLD Patients with Type 2 Diabetes

2019 ◽  
Vol 25 ◽  
pp. 199-200
Author(s):  
Prathyusha Chitrapu ◽  
Shilpa Jain ◽  
Aaron Thrift ◽  
Maya Balakrishnan ◽  
Ruchi Gaba
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Vitamin D Levels

Vitamin D levels are not associated with non-alcoholic fatty liver disease severity in a Brazilian population

2020 ◽  
pp. 1-8
Author(s):  
Jeniffer Danielle M. Dutra ◽  
Quelson Coelho Lisboa ◽  
Silvia Marinho Ferolla ◽  
Carolina Martinelli M. L. Carvalho ◽  
Camila Costa M. Mendes ◽  
...  
Keyword(s):  
Vitamin D ◽  
Liver Disease ◽  
Fatty Liver ◽  
Disease Severity ◽  
Fatty Liver Disease ◽  
Hypovitaminosis D ◽  
Alcoholic Fatty Liver ◽  
Vitamin D Levels ◽  
The Mean ◽  
Alcoholic Fatty Liver Disease

Abstract. Some epidemiological evidence suggests an inverse correlation between non-alcoholic fatty liver disease (NAFLD) frequency and vitamin D levels. Likewise, a beneficial effect of vitamin D on diabetes mellitus (DM) and insulin resistance has been observed, but this is an unsolved issue. Thus, we aimed to investigate the prevalence of hypovitaminosis D in a NAFLD Brazilian population and its association with disease severity and presence of comorbidities. In a cross-sectional study, the clinical, biochemical and histological parameters of 139 NAFLD patients were evaluated according to two different cut-off points of serum 25-hydroxyvitamin D levels (20 ng/mL and 30 ng/mL). The mean age of the population was 56 ± 16 years, most patients were female (83%), 72% had hypertension, 88% dyslipidemia, 46% DM, 98% central obesity, and 82% metabolic syndrome. Serum vitamin D levels were < 30 ng/mL in 78% of the patients, and < 20 ng/mL in 35%. The mean vitamin D level was 24.3 ± 6.8 ng/mL. The comparison between the clinical, biochemical and histological characteristics of the patients according to the levels of vitamin D showed no significant difference. Most patients with NAFLD had hypovitaminosis D, but low vitamin D levels were not related to disease severity and the presence of comorbidities.

Clinical factors correlated with vitamin D deficiency in patients with obesity scheduled for bariatric surgery: A single center experience

2020 ◽  
Vol 90 (3-4) ◽  
pp. 346-352
Author(s):  
Vincenzo Pilone ◽  
Salvatore Tramontano ◽  
Carmen Cutolo ◽  
Federica Marchese ◽  
Antonio Maria Pagano ◽  
...  
Keyword(s):  
Bariatric Surgery ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Inverse Correlation ◽  
Model Assessment ◽  
Cross Sectional ◽  
Serum Vitamin D ◽  
Female Sex ◽  
Vitamin D Levels

Abstract. We aim to assess the prevalence of vitamin D deficiency (VDD) in patients scheduled for bariatric surgery (BS), and to identify factors that might be associated with VDD. We conducted a cross-sectional observational study involving all consecutive patients scheduled for BS from 2017 to 2019. The exclusion criteria were missing data for vitamin D levels, intake of vitamin D supplements in the 3 months prior to serum vitamin D determination, and renal insufficiency. A total of 206 patients (mean age and body mass index [BMI] of 34.9 ± 10.7 years, and 44.3 ± 6.99 kg/m2, respectively) met the inclusion criteria and were enrolled for data analysis. VDD (<19.9 ng/mL), severe VDD (<10 ng/mL), and vitamin D insufficiency (20–29.9 ng/mL) were present in 68.8 %, 12.5 %, and 31.2 % of patients, respectively. A significant inverse correlation was found between vitamin D levels and initial BMI, parathyroid hormone, and homeostatic model assessment of insulin resistance (r = −0.280, p < 0.05; r = −0.407, p = 0.038; r = −0.445, p = 0.005), respectively. VDD was significantly more prevalent in patients with higher BMI [−0.413 ± 0.12, CI95 % (−0.659; −0.167), p = 0.006], whereas no significant association between hypertension [−1.005 ± 1.65, CI95 % (−4.338; 2.326), p = 0.001], and diabetes type 2 (T2D) [−0.44 ± 2.20, CI95 % (−4.876; 3.986), p = 0.841] was found. We observed significant association between female sex and levels of vitamin D [6.69 ± 2.31, CI95 % (2.06; 11.33), p = 0.006]. The present study shows that in patients scheduled for BS, VDD deficiency is common and was associated with higher BMI, and female sex.

Association of Vitamin D Status With Liver and Kidney Disease: A Systematic Review of Clinical Trials, and Cross-Sectional and Cohort Studies

2019 ◽  
pp. 1-13 ◽  
Author(s):  
Seyed Mostafa Parizadeh ◽  
Majid Rezayi ◽  
Reza Jafarzadeh-Esfehani ◽  
Amir Avan ◽  
Hamideh Ghazizadeh ◽  
...  
Keyword(s):  
Vitamin D ◽  
Kidney Disease ◽  
Renal Disease ◽  
Cohort Studies ◽  
Cochrane Library ◽  
Major Public Health Problem ◽  
Vitamin D Status ◽  
Cross Sectional ◽  
Beneficial Effects ◽  
Vitamin D Levels

Abstract. Background: Vitamin D deficiency (VDD) is a major public health problem. There are few comprehensive systematic reviews about the relationship between Vitamin D status and liver and renal disease in Iran. Methods: We systemically searched the following databases: Web of Science; PubMed; Cochrane Library; Scopus; Science Direct; Google Scholar and two Iranian databases (Scientific Information Database (SID) and IranMedex) up until November 2017 to identify all randomized control trials (RCTs), case control, cross-sectional and cohort studies investigating the association between vitamin D and any form of liver or kidney disease. Results: Vitamin D insufficiency, or deficiency (VDD), is highly prevalent in Iran, reports varying between 44.4% in Isfahan to 98% in Gorgan. There is also a high prevalence of VDD among patients with liver or kidney disease, and the administration of vitamin D supplements may have beneficial effects on lipid profile, blood glucose, liver function and fatty liver disease, and bone health. Low serum vitamin D levels are related with abnormalities in these laboratory and clinical parameters. Conclusion: VDD is prevalent in patients with chronic liver or renal disease in Iran. There appear to be several beneficial effects of vitamin D supplementation in vitamin D deficient patients with liver or kidney disease.

Low Vitamin D Levels May Explain Pediatric Pain

2008 ◽  
Vol 38 (11) ◽  
pp. 24
Author(s):  
JANE SALODOF MACNEIL
Keyword(s):  
Vitamin D ◽  
Pediatric Pain ◽  
Vitamin D Levels
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