scholarly journals Curcumin Enhanced the Neomucosa Formation by Mediating the Antioxidation Mechanism in Rats

2021 ◽  
Author(s):  
Nadir Adnan Hacim
Keyword(s):  
Antioxidation Mechanism

A proposed antioxidation mechanism of ergothioneine based on the chemically-derived oxidation product hercynine and further decomposition products

2021 ◽  
Author(s):  
Chika Ando ◽  
Yasujiro Morimitsu
Keyword(s):  
Hydrogen Peroxide ◽  
Oxidation Mechanism ◽  
Major Product ◽  
Oxidation Products ◽  
Liquid Chromatography Mass Spectrometry ◽  
Decomposition Products ◽  
Physiological Conditions ◽  
Chemical Oxidants ◽  
Mechanism Of Oxidation ◽  
Antioxidation Mechanism

Abstract Ergothioneine (ERGO), a thiohistidine betaine, exists in various fungi, plants, and animals. Humans take in ERGO from their diet. ERGO is a strong biological antioxidant, but there are only a limited number of reports about its redox mechanism. The purpose of this study was to clarify the oxidation mechanism of ERGO. Reactions of ERGO with chemical oxidants were performed. The oxidation products of ERGO were analyzed by nuclear magnetic resonance and liquid chromatography-mass spectrometry (LC-MS). The major product of oxidation of ERGO by hydrogen peroxide in physiological conditions was identified as hercynine (histidine betaine). One molecule of ERGO was able to reduce two molecules of hydrogen peroxide. Hercynine was found to react with the more potent oxidant hypochlorite. One unstable decomposition product was detected by LC-MS. As a result, a mechanism of oxidation of ERGO, and hence its physiological antioxidant activity, was developed.

Antioxidation Mechanism Studies of Caffeic Acid: Identification of Antioxidation Products of Methyl Caffeate from Lipid Oxidation

2008 ◽  
Vol 56 (14) ◽  
pp. 5947-5952 ◽  
Author(s):  
Toshiya Masuda ◽  
Kazuki Yamada ◽  
Jun Akiyama ◽  
Tatsushi Someya ◽  
Yuka Odaka ◽  
...  
Keyword(s):  
Lipid Oxidation ◽  
Caffeic Acid ◽  
Methyl Caffeate ◽  
Antioxidation Mechanism
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