scholarly journals Subfoveal Choroidal Thickness And Ganglion Cell Complex In Children With Type 1 Diabetes Mellitus Without Diabetic Retinopathy

2020 ◽  
Author(s):  
alper halil bayat
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Type 1 Diabetes Mellitus ◽  
Ganglion Cell ◽  
Choroidal Thickness ◽  
Cell Complex ◽  
Ganglion Cell Complex ◽  
Subfoveal Choroidal Thickness

scholarly journals Microalbuminuria is associated with increased choroidal thickness in type 1 diabetes mellitus patients without diabetic retinopathy

2017 ◽  
Vol 96 (1) ◽  
pp. e95-e97 ◽  
Author(s):  
Fernando Korn Malerbi ◽  
Caio Vinicius Regatieri ◽  
João Roberto de Sa ◽  
Paulo Henrique Morales ◽  
Michel Eid Farah ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Type 1 Diabetes Mellitus ◽  
Choroidal Thickness

Evaluation of Subfoveal Choroidal Thickness in Children with Type 1 Diabetes Mellitus: An EDI-OCT Study

2013 ◽  
Vol 29 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Nihat Sayin ◽  
Necip Kara ◽  
Dilara Pirhan ◽  
Asli Vural ◽  
Hatice Bilge Araz Ersan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Choroidal Thickness ◽  
Subfoveal Choroidal Thickness

scholarly journals Choroidal Thickness and Ganglion Cell Complex in Pubescent Children with Type 1 Diabetes without Diabetic Retinopathy Analyzed by Spectral Domain Optical Coherence Tomography

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Joanna Gołębiewska ◽  
Andrzej Olechowski ◽  
Marta Wysocka-Mincewicz ◽  
Marta Baszyńska-Wilk ◽  
Artur Groszek ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Type 1 Diabetes ◽  
Ganglion Cell ◽  
Hba1c Level ◽  
Choroidal Thickness ◽  
Cell Complex ◽  
Ganglion Cell Complex ◽  
Significant Difference ◽  
Sd Oct

Aim. To assess the retinal and choroidal thickness and ganglion cell complex (GCC) in pubescent children with type 1 diabetes (T1D) without diabetic retinopathy (DR), using spectral domain optical coherence tomography (SD-OCT). Materials and Method. Sixty-four right eyes of 64 subjects with T1D and 45 right eyes of 45 age-matched healthy volunteers (control group) were enrolled in this study. The mean age of the subjects and controls was 15.3 (±SD = 2.2) and 14.6 (±SD = 1.5), respectively. SD-OCT was performed using RTVue XR Avanti. Ganglion cell complex (GCC), GCC focal loss volume (FLV), GCC global loss volume (GLV), choroidal thickness (CT), foveal (FT) and parafoveal thickness (PFT), and foveal (FV) and parafoveal volume (PFV) data were analyzed. Results. There was no significant difference between subjects and controls in the CT in the fovea and nasal, temporal, superior, and inferior quadrants of the macula. There were no significant correlations between CT, duration of diabetes, and HbA1C level (p=0.272 and p=0.197, resp.). GCC thickness did not differ significantly between the groups (p=0.448), but there was a significant difference in FLV (p=0.037). Significant differences between the groups were found in the PFT and PFV (p=0.004 and p=0.005, resp.). There was a significant negative correlation between PFT, PFV, and HbA1C level (p=0.002 and p=0.001, resp.). Conclusions. Choroidal thickness remains unchanged in children with T1D. Increased GCC FLV might suggest an early alteration in neuroretinal tissue. Parafoveal retinal thickness is decreased in pubescent T1D children and correlates with HbA1C level. OCT can be considered a part of noninvasive screening in children with T1D and a tool for early detection of retinal and choroidal abnormalities. Further OCT follow-up is needed to determine whether any of the discussed OCT measurements are predictive of future DR severity.

Retinal Ganglion Cell Loss in Children With Type 1 Diabetes Mellitus Without Diabetic Retinopathy

2017 ◽  
Vol 48 (6) ◽  
pp. 473-477 ◽  
Author(s):  
Omer Karti ◽  
Ozlem Nalbantoglu ◽  
Saygin Abali ◽  
Ziya Ayhan ◽  
Selma Tunc ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Type 1 Diabetes Mellitus ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Loss ◽  
Retinal Ganglion

scholarly journals The Effect of HbA1c Variability as a Risk Measure for Microangiopathy in Type 1 Diabetes Mellitus

Diagnostics ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1151
Author(s):  
Pedro Romero-Aroca ◽  
Raul Navarro-Gil ◽  
Albert Feliu ◽  
Aida Valls ◽  
Antonio Moreno ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Retinopathy ◽  
Type 1 Diabetes Mellitus ◽  
Risk Measure ◽  
Case Series ◽  
Multivariate Statistical ◽  
Case Series Study ◽  
Prospective Case Series

Background: To measure the relationship between variability in HbA1c and microalbuminuria (MA) and diabetic retinopathy (DR) in the long term. Methods: A prospective case-series study, was conducted on 366 Type 1 Diabetes Mellitus patients with normoalbuminuria and without diabetic retinopathy at inclusion. The cohort was followed for a period of 12 years. The Cox survival analysis was used for the multivariate statistical study. The effect of variability in microangiopathy (retinopathy and nephropathy) was evaluated by calculating the standard deviation of HbA1c (SD-HbA1c), the coefficient of variation of HbA1c (CV-HbA1c), average real variability (ARV-HbA1c) and variability irrespective of the mean (VIM-HbA1c) adjusted for the other known variables. Results: A total of 106 patients developed diabetic retinopathy (29%) and 73 microalbuminuria (19.9%). Overt diabetic nephropathy, by our definition, affected only five patients (1.36%). Statistical results show that the current age, mean HbA1c, SD-HbA1c and ARV-HbA1c are significant in the development of diabetic retinopathy. Microalbuminuria was significant for current age, mean HbA1c, CV-HbA1c and ARV-HbA1c. Conclusions: By measuring the variability in HbA1c, we can use SD-HbA1c and ARV-HbA1c as possible targets for judging which patients are at risk of developing DR and MA, and CV-HbA1c as the target for severe DR.

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