scholarly journals Evaluation of clinical findings, optical coherence tomography, fundus flourescein angiography and indocyanine green angiography imaging in patients with Polypoidal Choroidal Vasculopathy

2020 ◽  
Author(s):  
Rüveyde Garip
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Polypoidal Choroidal Vasculopathy ◽  
Indocyanine Green Angiography ◽  
Clinical Findings ◽  
Optical Coherence ◽  
Choroidal Vasculopathy

scholarly journals Polypoidal Choroidal Vasculopathy in Congolese Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Nelly N. Kabedi ◽  
David L. Kayembe ◽  
Gloria M. Elongo ◽  
Jean-Claude Mwanza
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Polypoidal Choroidal Vasculopathy ◽  
Indocyanine Green Angiography ◽  
Clinical Presentation ◽  
Case Series ◽  
Systemic Hypertension ◽  
Optical Coherence ◽  
Blurred Vision ◽  
Choroidal Vasculopathy

Purpose. Polypoidal choroidal vasculopathy (PCV) is a visually debilitating disease that mostly affects people of African and Asian heritage. Indocyanine green angiography (ICGA) is the recommended exploratory method for definitive diagnosis. The disease has been extensively described in Asians and Caucasians, but not in Africans. This study was conducted to document the clinical presentation and optical coherence tomography features of polypoidal choroidal vasculopathy (PCV) in Congolese patients. Methods. A prospective case series of patients with PCV was performed between January 2017 and June 2019. Routine ocular examination was performed including best corrected visual acuity measurement, slit-lamp examination, dilated direct fundoscopy, and spectral domain optical coherence tomography (OCT). The diagnosis was based on a combination of clinical and OCT signs. Results. Fourteen patients were diagnosed with PCV during this period. The average age was 64.7 ± 6.9 years. There were 8 females. Ten (71.4%) patients had systemic hypertension. Most patients (n = 9, 64.3%) had bilateral involvement. Blurred vision was the most common complaint (71.4%). The main clinical presentation was subretinal exudates, seen in 19 (82.6%) eyes of 11 (78.6%) patients and subretinal hemorrhage in 10 (43.5%) eyes. Macular localization was found in 16 eyes (69.5%) of 12 (85.7%) patients. Drusen were observed in 35.7% of the patients. On OCT imaging, thumb-like pigment epithelial detachment and subretinal exudation were the most frequent features, observed in 92.9% and 71.4% of the patients, respectively. Conclusions. PCV in Congolese patients showed features that are more similar to those observed in Caucasians. In this setting where indocyanine green angiography is not available, OCT facilitates the diagnosis of PCV.

scholarly journals Comparison of Indocyanine Green Angiography and Optical Coherence Tomography Angiography for Polypoidal Choroidal Vasculopathy

2021 ◽  
Vol 62 (9) ◽  
pp. 1198-1206
Author(s):  
Jonghyun Kim ◽  
So Min Ahn ◽  
Cheolmin Yun ◽  
Seong-Woo Kim ◽  
Jaeryung Oh
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Polypoidal Choroidal Vasculopathy ◽  
Indocyanine Green Angiography ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Polyp Detection Rate ◽  
Group 2 ◽  
Choroidal Vasculopathy ◽  
Group 1

Purpose: To assess the diagnostic value of optical coherence tomography angiography (OCTA), and the factors affecting the diagnosis of polypoidal choroidal vasculopathy (PCV) by OCTA and indocyanine green angiography (ICGA). Methods: The numbers and area of polyps, and the presence and area of a branched vascular network (BVN) as revealed by ICGA and OCTA, were retrospectively analyzed in 43 patients with active PCV. The patients were divided into two groups according to whether the number of polyps matched between the two methods: group 1, equal number of polyps revealed by ICGA and OCTA; group 2, different number of polyps revealed by ICGA and OCTA. Results: In 43 PCV patients, the total number of polyps was 1.47 ± 0.83 in ICGA and 1.07 ± 0.91 in OCTA (<i>p</i> < 0.001), and the polyp area was 0.27 ± 0.42 mm<sup>2</sup> in ICGA and 0.17 ± 0.15 mm<sup>2</sup> in OCTA (<i>p</i> = 0.023). BVN was found in 33 eyes (76.7%) by ICGA and 29 eyes (67.4%) by OCTA (<i>p</i> < 0.001). The BVN area was 3.61 ± 2.59 mm<sup>2</sup> in ICGA and 2.74 ± 2.76 mm<sup>2</sup> in OCTA (<i>p</i> = 0.002). Central retinal thickness and central choroidal thickness were significantly greater in group 2 than group 1 (<i>p</i> < 0.001, respectively). Subretinal fluid (SRF) (<i>p</i> = 0.009) and subretinal hemorrhage (SRH) (<i>p</i> = 0.005) were significantly more prevalent in group 2 than group 1. Polyp height (<i>p</i> = 0.022) and diameter (<i>p</i> = 0.042) were significantly greater in group 2 than group 1. Conclusions: OCTA is a supplementary diagnostic technique for detecting PCV. The presence of SRF and SHR, and large polyp height and diameter, were associated with the polyp detection rate of OCTA for PCV.

Angiographic features of polypoidal choroidal vasculopathy using indocyanine green angiography and optical coherence tomography angiography: A comparative study

2019 ◽  
Vol 30 (5) ◽  
pp. 1076-1081
Author(s):  
Sumit Randhir Singh ◽  
Prakhar Goyal ◽  
Deepika C Parameswarappa ◽  
Abhilash Goud ◽  
Jay Chhablani
Keyword(s):  
Optical Coherence Tomography ◽  
Indocyanine Green ◽  
Polypoidal Choroidal Vasculopathy ◽  
Indocyanine Green Angiography ◽  
Optical Coherence Tomography Angiography ◽  
Network Size ◽  
Vascular Network ◽  
Optical Coherence ◽  
Branching Vascular Network ◽  
Choroidal Vasculopathy

Background: To compare the vascular lesion size using optical coherence tomography angiography and indocyanine green angiography in eyes with polypoidal choroidal vasculopathy. Methods: Treatment-naïve cases (46 eyes of 44 patients) with polypoidal choroidal vasculopathy were retrospectively analyzed. The comparison of mean area of branching vascular network and polyp detection rate was done between indocyanine green angiography and optical coherence tomography angiography and correlated with various optical coherence tomography features. Results: The mean age of the study patients was 62.33 ± 10.74 years. The mean branching vascular network size was 7.47 ± 5.74 and 7.51 ± 5.69 mm² in indocyanine green angiography and optical coherence tomography angiography, respectively, with an excellent correlation (r = 0.997). Optical coherence tomography angiography overestimated (mean ± SD: 0.28 ± 0.19 mm²) and underestimated branching vascular network area (0.36 ± 0.33 mm²) in 23 eyes each as compared to indocyanine green angiography. However, the difference in branching vascular network size was not statistically significant (p = 0.53). Indocyanine green angiography and optical coherence tomography angiography could identify polyps in 43 of 46 (93.48%) and 32 of 46 (69.57%) patients, respectively. Conclusion: Branching vascular network size measurements with indocyanine green angiography and optical coherence tomography angiography were comparable and showed significant correlation, albeit the polyp identification rate was lower with optical coherence tomography angiography. Optical coherence tomography angiography may serve as a useful substitute to indocyanine green angiography in measurements of branching vascular network for photodynamic therapy and follow-up of polypoidal choroidal vasculopathy eyes.

Polypoidal Choroidal Vasculopathy Secondary to Sclerochoroidal Calcification

2017 ◽  
Vol 1 (6) ◽  
pp. 431-434
Author(s):  
Helen Hyun-Jin Do ◽  
Adrian T. Fung ◽  
Alex P. Hunyor ◽  
I-Van Ho ◽  
Gerald Liew
Keyword(s):  
Optical Coherence Tomography ◽  
Case Report ◽  
Polypoidal Choroidal Vasculopathy ◽  
Multimodal Imaging ◽  
Indocyanine Green Angiography ◽  
Optical Coherence ◽  
Single Patient ◽  
Patient Case ◽  
Retinal Hemorrhages ◽  
Choroidal Vasculopathy

Purpose: To present a case of polypoidal choroidal vasculopathy secondary to sclerochoroidal calcification. Method: A single patient case report with multimodal imaging including color fundus, red free and autofluorescence photography, fluorescein and indocyanine green angiography, and optical coherence tomography. Results: Sclerochoroidal calcification was diagnosed clinically from bilateral retinal elevations and underlying subretinal yellow deposits. The presence of retinal hemorrhages was confirmed to be secondary to underlying polypoidal choroidal vasculopathy by optical coherence tomography and fundus angiography. Conclusion: Sclerochoroidal calcification may be complicated by polypoidal choroidal vasculopathy.

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