scholarly journals Synchronous Presence of EGFR, ALK Driver Mutations Along With PD L1 Overexpression in a Resected Early Stage Non-Small Cell Lung Cancer: A Case Report and Review of Literature

2018 ◽  
Vol 9 (2) ◽  
pp. 50-55
Author(s):  
Nishitha Thumallapally ◽  
Sara Parylo ◽  
Adarsh Vennepureddy ◽  
Uroosa Ibrahim ◽  
Alisa Sokoloff
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Small Cell ◽  
Driver Mutations ◽  
Review Of Literature ◽  
Small Cell Lung

scholarly journals Chemotherapy plus atezolizumab for a patient with small cell lung cancer undergoing haemodialysis: a case report and review of literature

2021 ◽  
Vol 9 (5) ◽  
Author(s):  
Mihoko Imaji ◽  
Daichi Fujimoto ◽  
Mai Kato ◽  
Masanori Tanaka ◽  
Katsuyuki Furuta ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Review Of Literature ◽  
Small Cell Lung

scholarly journals P3-105: Response to erlotinib in the neoadjuvant setting for early stage non–small cell lung cancer (NSCLC): a case report

2007 ◽  
Vol 2 (8) ◽  
pp. S723-S724
Author(s):  
Ingrid Kappers ◽  
Jacobus A. Burgers ◽  
Herman Rijna ◽  
Henk E. Codrington ◽  
Anne-Marie Dingemans ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Early Stage ◽  
Small Cell ◽  
Small Cell Lung

Mutational landscape of early-stage non-small cell lung cancer patients using a 451 gene panel.

2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e20048-e20048
Author(s):  
Guanxian Mao ◽  
Peng Xuxing ◽  
Wu Hao ◽  
Wang Junbing ◽  
Liu Suyue ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Detection Rate ◽  
Early Stage ◽  
Small Cell ◽  
Driver Mutations ◽  
Small Cell Lung ◽  
Early Stage Nsclc ◽  
Nsclc Patients

e20048 Background: Many studies have reported mutation landscapes of non-small cell lung cancer (NSCLC), but most of the data were from advanced-stage patients. This study reports the mutation landscape of early-stage NSCLC patients. Methods: Many studies have reported mutation landscapes of non-small cell lung cancer (NSCLC), but most of the data were from advanced-stage patients. This study reports the mutation landscape of early-stage NSCLC patients. Results: In all, 74 tDNA and ctDNA samples were analyzed. A total of 285 mutations were identified, including 174 in tDNA and 111 in plasma ctDNA. Genes with the highest -frequencies of mutations in tDNA were EGFR, TP53, KMT2B, BRAF, PIK3CA, CDKN2A, and KRAS,while TP53, EGFR, NOTCH3, PIK3CA, andATM were the genes with the highest frequencies of mutations in ctDNA. The detection rate of driver mutations in tDNA and ctDNA, respectively, were: 42.9% (15/35) and 12.8% (5/39) for EGFR, 5.7% (2/35) and 2.6% (1/39) for ALK, 5.7% (2/35) and 2.6% (1/39) for ERBB2, 11.4% (4/35) and 0%)0/39) for BRAF,5.7% (2/35) and 0%)0/39) for RET, 37% (13/35) and 23.1% (9/39) for TP53. Conclusions: In all, 74 tDNA and ctDNA samples were analyzed. A total of 285 mutations were identified, including 174 in tDNA and 111 in plasma ctDNA. Genes with the highest -frequencies of mutations in tDNA were EGFR, TP53, KMT2B, BRAF, PIK3CA, CDKN2A, and KRAS,while TP53, EGFR, NOTCH3, PIK3CA, andATM were the genes with the highest frequencies of mutations in ctDNA. The detection rate of driver mutations in tDNA and ctDNA, respectively, were: 42.9% (15/35) and 12.8% (5/39) for EGFR, 5.7% (2/35) and 2.6% (1/39) for ALK, 5.7% (2/35) and 2.6% (1/39) for ERBB2, 11.4% (4/35) and 0% )0/39) for BRAF,5.7% (2/35) and 0% )0/39) for RET, 37% (13/35) and 23.1% (9/39) for TP53.

scholarly journals Tyrosine Kinase Inhibitors in the Treatment of Choroidal Metastases from Non-Small-Cell Lung Cancer: A Case Report and Review of Literature

2016 ◽  
Vol 3 (1) ◽  
pp. 28-33 ◽  
Author(s):  
Akshay Gopinathan Nair ◽  
Haresh T. Asnani ◽  
Vinod C. Mehta ◽  
Siddharth V. Mehta ◽  
Rima S. Pathak ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Tyrosine Kinase ◽  
Small Cell Lung Cancer ◽  
Tyrosine Kinase Inhibitors ◽  
Cell Lung Cancer ◽  
Kinase Inhibitors ◽  
Small Cell ◽  
Review Of Literature ◽  
Small Cell Lung

scholarly journals Small Cell Lung Cancer Invading the Left Atrium With Subsequent Malignant Embolic Stroke: A Case Report and Review of Literature

2019 ◽  
Vol 10 (3) ◽  
pp. 188-192 ◽  
Author(s):  
Raghav Chandra ◽  
Ashraf Abugroun ◽  
Alan Goldberg ◽  
Elizabeth Cooney ◽  
Swati Mehrotra ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Small Cell Lung Cancer ◽  
Left Atrium ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Embolic Stroke ◽  
Review Of Literature ◽  
Small Cell Lung
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