Prospective Study of Fractional Carbon Dioxide Laser Therapy for Symptoms of Genitourinary Syndrome of Menopause: One-Year Follow-Up

2021 ◽  
Vol 10 (1) ◽  
pp. 11-17
Author(s):  
Jeffrey S. Schachar ◽  
Hemikaa Devakumar ◽  
Laura Martin ◽  
Eric A. Hurtado ◽  
G. Willy Davila
2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Vasanop Vachiramon ◽  
Pattarin Anusaksathien ◽  
Silada Kanokrungsee ◽  
Kumutnart Chanprapaph

Objective. Keratosis pilaris (KP) is a common condition which can frequently be cosmetically disturbing. Topical treatments can be used with limited efficacy. The objective of this study is to evaluate the effectiveness and safety of fractional carbon dioxide (CO2) laser for the treatment of KP.Patients and Methods. A prospective, randomized, single-blinded, intraindividual comparative study was conducted on adult patients with KP. A single session of fractional CO2laser was performed to one side of arm whereas the contralateral side served as control. Patients were scheduled for follow-up at 4 and 12 weeks after treatment. Clinical improvement was graded subjectively by blinded dermatologists. Patients rated treatment satisfaction at the end of the study.Results. Twenty patients completed the study. All patients stated that the laser treatment improved KP lesions. At 12-week follow-up, 30% of lesions on the laser-treated side had moderate to good improvement according to physicians’ global assessment (p=0.02). Keratotic papules and hyperpigmentation appeared to respond better than the erythematous component. Four patients with Fitzpatrick skin type V developed transient pigmentary alteration.Conclusions. Fractional CO2laser treatment may be offered to patients with KP. Dark-skinned patients should be treated with special caution.


Author(s):  
Jennifer Zuccaro ◽  
Charis Kelly ◽  
Manuela Perez ◽  
Andrea Doria ◽  
Joel S Fish

Abstract Laser therapy has become a valuable treatment option for hypertrophic burn scars. Improvements in scar symptoms have been achieved using the ablative fractional carbon dioxide laser as well as the pulsed dye laser. However, research regarding the use of laser therapy among pediatric patients remains limited. Thus, the aim of this study was to investigate the effectiveness of using laser therapy to improve hypertrophic burn scars in a pediatric population using a comprehensive scar assessment protocol. A pragmatic, single-center, prospective observational study was conducted at a tertiary pediatric hospital. Twenty participants with hypertrophic burn scars were included. Laser procedures were administered at approximately two month intervals and scars were evaluated at five time-points over one year using the Vancouver Scar Scale, the Patient and Observer Scar Assessment Scale, conventional ultrasound, ultrasound elastography, and a multi-probe skin analysis device. Seventy-one laser procedures were performed with most participants receiving treatment with both the ablative fractional carbon dioxide laser and the pulsed dye laser at the same session (83%). From baseline to study completion, significant improvements in all scar measures were observed (p < 0.05). In particular, improvements in overall scarring and in specific scar properties including thickness, stiffness, and colour were found (p < 0.05). To our knowledge, this is the most comprehensive study to date to evaluate the effect of laser treatment on hypertrophic burn scars in a pediatric population. Our findings suggest that laser therapy is a beneficial treatment for burn-injured children as evidenced by the improvements in subjective and objective scar assessment measures.


2016 ◽  
Vol 2016 ◽  
pp. 1-7 ◽  
Author(s):  
Farahnaz Fatemi Naeini ◽  
Shadi Behfar ◽  
Bahareh Abtahi-Naeini ◽  
Shima Keyvan ◽  
Mohsen Pourazizi

Background. A consistent treatment has not been proposed for treatment of Striae Alba (SA). The present study was designed to compare the fractionated microneedle radiofrequency (FMR) alone and in combination with fractional carbon dioxide laser (FMR + CO2) in the treatment of SA.Methods. Forty-eight pairs of SA from six patients were selected. Right or left SAs were randomly assigned to one of the treatment groups. The surface area of the SA before and after treatment and clinical improvement using a four-point scale were measured at the baseline, after one and three months.Results. The mean age of the patients was30.17±5.19years. The mean difference of the surface area between pre- and posttreatment in the FMR + CO2group was significantly higher than that in the FMR group (p=0.003). Clinical improvement scales showed significantly higher improvement in the FMR + CO2group than in the FMR group in the first and second follow-up (p=0.002and 0.004, resp.). There were no major persistence side-effects in both groups.Conclusions. The results showed that FMR + CO2laser was more effective than FMR alone in the treatment of SA.


Sign in / Sign up

Export Citation Format

Share Document