Long-term functional outcomes and quality of life after restorative proctocolectomy and ileal pouch-anal anastomosis

2016 ◽  
Vol 70 (1) ◽  
pp. 38-44
Author(s):  
Marta Kostrejová ◽  
Martin Bortlík ◽  
Dana Ďuricová ◽  
Martin Kolář ◽  
Richard Sequens ◽  
...  
2019 ◽  
Vol 14 (6) ◽  
pp. 726-733 ◽  
Author(s):  
Pramodh Chandrasinghe ◽  
Michele Carvello ◽  
Karin Wasmann ◽  
Caterina Foppa ◽  
Pieter Tanis ◽  
...  

Abstract Background The transanal approach to ileal pouch-anal anastomosis [Ta-IPAA] provides better access to the lower pelvis with lower short-term morbidity in ulcerative colitis [UC]. The aim of this study was to assess the long-term functional outcomes after Ta-IPAA vs transabdominal IPAA [Abd-IPAA] in UC. Methods A multicentre cohort analysis was performed between March 2002 and September 2017. Patient characteristics, surgical details and postoperative outcomes were compared. CGQL [Cleveland global quality of life] score at 12 months with a functioning pouch was considered the primary end point. Results A total of 374 patients [100 Ta-IPAA vs 274 Abd-IPAA] were included. Ta-IPAA demonstrated a comparable overall quality of life [CGQL score] to Abd-IPAA [0.75 ± 0.11 vs 0.71 ± 0.14; respectively, p = 0.1]. Quality of life [7.71 ± 1.17 vs 7.30 ± 1.46; p = 0.04] and energy-level items [7.16 ± 1.52 vs 6.66 ± 1.68; p = 0.03] were significantly better after Ta-IPAA, while the quality of health item was comparable [7.68 ± 1.26 vs 7.64 ± 1.44; p = 0.96]. Analysis excluding anastomotic leaks did not change the overall CGQL scores. Stool frequencies [>10/24 h: 22% vs 21%; p = 1.0] and the rate of a single episode of major incontinence during the following 12-month period [27% vs 26%; p = 0.89] were similar. The differences in 30-day morbidity rates [33% vs 41%; p = 0.2] and anastomotic leak rates were not significant [6% vs 13%; p = 0.09]. Conclusions This study provides evidence of comparable long-term functional outcome and quality of life after Ta-IPAA and Abd-IPAA for UC.


2018 ◽  
Vol 23 (3) ◽  
pp. 571-579 ◽  
Author(s):  
Olga A. Lavryk ◽  
Luca Stocchi ◽  
Tracy L. Hull ◽  
Emre Gorgun ◽  
Sherief Shawki ◽  
...  

Author(s):  
ADRIANA CHEREM-ALVES ◽  
ANTÔNIO LACERDA-FILHO ◽  
PRISCILA FERNANDES ALVES ◽  
MAGDA PROFETA-DA-LUZ ◽  
JULIANO ALVES FIGUEIREDO ◽  
...  

ABSTRACT Purpose: restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice in some cases of familial adenomatous polyposis (FAP) and ulcerative colitis (UC). IPAA allows complete removal of the diseased colon and rectum, however, it is associated with substantial morbidity and potential consequences to patients’ quality of life (QoL). Aims: to evaluate the surgical results, functional outcomes and QoL after IPAA; and to examine the impact of surgical complications upon QoL. Methods: we reviewed the records of 55 patients after IPAA, with emphasis on surgical outcomes. Forty patients answered the questionnaires. The Cleveland Global Quality of Life (CGQL), Inflammatory Bowel Disease Questionnaire (IBDQ), and Short Form 36 Health Survey Questionnaire (SF36). Results: the average age was 42.1±14.1 years. 63.6% of the patients were male, and 69.1% had FAP. Operative mortality was 1.8% and overall morbidity was 76.4%. Anastomotic leakage was the most frequent early complication (34.5%). Pouchitis (10.8%) and small bowel obstruction (9.1%) were the most common late complications. Patients with UC had the most severe complications (p=0.014). Pelvic complications did not have a negative effect on functional outcomes or QoL scores. Female patients had decreased pouch evacuation frequency, fewer nocturnal bowel movements, decreased bowel symptom impact on QoL (p=0.012), and better CGQL (p=0.04). Patients with better education had better QoL scores, and patients who had their pouches for more than five years scored lower. Conclusion: the high morbidity has no impact on function or QoL. Bowel function is generally acceptable. QoL is good and affected by sex, education and time interval since IPAA.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Eren Esen ◽  
Michael J. Grieco ◽  
Arman Erkan ◽  
Erman Aytac ◽  
Alton G. Sutter ◽  
...  

2014 ◽  
Vol 8 ◽  
pp. S424 ◽  
Author(s):  
J.M. Bakia ◽  
P.H.A. Bours ◽  
D.M.A.E. Jonkers ◽  
L.W.E. van Heurn ◽  
M.J. Pierik ◽  
...  

1992 ◽  
Vol 16 (6) ◽  
pp. 1126-1131 ◽  
Author(s):  
Lothar W. Köhler ◽  
John H. Pemberton ◽  
David O. Hodge ◽  
Alan R. Zinsmeister ◽  
Keith A. Kelly

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