scholarly journals Medicinal importance of avicularin as potential anti-inflammatory agents for the treatment of liver disorders: Therapeutic assessment and biological importance in the medicine

2021 ◽  
Vol 25 (1) ◽  
pp. S296-S296
Author(s):  
Dinesh Kumar PATEL
2018 ◽  
Vol 8 (5) ◽  
pp. 88-91
Author(s):  
Aisha Siddiqui ◽  
Zeba Afrin ◽  
MA Jafri

Lavandula stoechas Mill. commonly known as Ustukhudoos, is perhaps the most important medicinal plant in the unani system of medicine. Whole part, flowers and essential oil of the plant is used to treat a variety of diseases. A number of ailments are treated by the plant which is used either alone or in combination with other plants. It is used for the treatment of various neurological disorders like hemiplegia, facial paralysis, tremors, epilepsy, melancholia, neurasthenia. Moreover, it is used in sinusitis, liver disorders and urinary disorders etc. L. stoechas possesses antimicrobial, antidiabetic, antioxidant, antifungal, anti-inflammatory, anticonvulsant, antispasmodic, sedative, hepatoprotective activities. This article discusses and summarizes the important medicinal values of Ustukhudoos in the perspective of Unani literature as well as modern scientific research. Keywords: Ustukhudoos, Lavandula stoechas, neurological, epilepsy


2021 ◽  
Vol 17 ◽  
Author(s):  
Kanika Patel ◽  
Dinesh Kumar Patel

Background: Herbal drugs and their derived phytochemicals have been used in medicine for the preparation of different types of pharmaceutical products. Pure phytochemicals including flavonoids, alkaloids and terpenoids have been used in medicine for the treatment of different types of human disorders including cancerous disorders. Flavonoids have been well known in medicine for their anti-viral, anti-bacterial, anti-inflammatory, anti-diabetic, anti-cancer, anti-aging and cardioprotective potential. Avicularin, also called quercetin-3-α-l-arabino furanoside, is a pure flavonoid, a class of phytochemicals, found to be present in Lindera erythrocarpa and Lespedeza cuneata. Avicularin has been well known in medicine for its anti-cancer properties. Methods: In the present work, scientific data of avicularin have been collected from different databases such as Google, PubMed, Science Direct, Google Scholar and Scopus and summarized with reference to medicinal importance, pharmacological activities and analytical aspects of avicularin. The present review summarized the health beneficial properties of avicularin in medicine through data analysis of various scientific research works. Further analytical progress in medicine for the qualitative and quantitative analysis of avicularin in medicine has been also discussed in the present work. Results: Scientific data analysis of different literature work revealed the biological importance of flavonoid class of phytochemical ‘avicularin’ in medicine. Scientific data analysis revealed that avicularin was found to be present in the Lindera erythrocarpa, Lespedeza cuneata, Rhododendron schlipenbachii and Psidium guajava. Avicularin has been well known in medicine for its anti-inflammatory, anti-allergic, anti-oxidant, anti-tumor and hepatoprotective activities. Avicularin protects cardiomyocytes and hepatocytes against oxidative stress-induced apoptosis and induces cytotoxicity in cancer lines and tumor tissues. Avicularin has positive influence on human hepatocellular carcinoma and inhibits intracellular lipid accumulation. The role of avicularin in rheumatoid arthritis has been also established with its underlying molecular mechanisms in the scientific work. Recent interest in avicularin has focused on pharmacological investigations for its anti-cancer activity in the medicine. Conclusion: The present work signified the biological importance of avicularin in medicine through its medicinal uses, pharmacological activities and analytical aspects in the biological system.


2019 ◽  
Vol 20 (3) ◽  
Author(s):  
Izabela Czapska-Pietrzak ◽  
Elżbieta Studzińska-Sroka ◽  
Wiesława Bylka

Geum urbanum L. (St. Benedict’s herb, Wood Avens) belonging to Rosaceae family, is a perennial herb occuring in the moderate zone of both Hemispheres. The roots and rhizomes containing: tannins, especially ellagitannins (mainly gemin), essential oil (mainly gein), flavonoids, proanthocyanidins, triterpenes, carbohydrates. In folk medicine it was used in gastro-enteritis and liver disorders, and to induce cardiogenesis also externally for reducing the gingivitis. The results of experiments on: antimicrobial, anti-inflammatory, cardiogenic and antioxidant effects were presented.


INDIAN DRUGS ◽  
2012 ◽  
Vol 49 (12) ◽  
pp. 23-28
Author(s):  
V. Neeharika ◽  
◽  
T. Swetha ◽  
F Humaira ◽  
B. M Reddy ◽  
...  

Croton caudatus (Euphorbiaceae) is claimed to be useful in treatment of sprains, arthritis and liver disorders in traditional system of medicine. In the present investigation antinociceptive, anti-inflammatory and antipyretic effects of the 80% aqueous ethanolic extract from leaves of C. caudatus have been evaluated. The ethanolic extract reduced the nociception induced by acetic acid at dose of 100, 200 and 400 mg/kg significantly (P<0.001) and in dose dependent manner. In the hot plate test, the extract significantly increased the latency time of jump. The naloxone reversed the antinociception of the extract in hot plate test, indicating that C. caudatus ethanolic extract has morphinomimetic properties. The extract significantly decreased the rectal temperature in yeast-induced pyrexia in rats at highest tested dose.The ethanolic extract at a dose of 400 mg/kg produced 47% protection in carrageenan-induced edema. Steroids and/or triterpenoids, flavonoids and their glycosides are the major constituents of ethanolic extract of C. caudatus.


1979 ◽  
Vol 7 (6) ◽  
pp. 1323-1323
Author(s):  
H. DANIELSSON

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