scholarly journals Laparoscopic pancreaticoduodenectomy for periampullary tumors: A contraindication for octogenarians?

2021 ◽  
Vol 25 (1) ◽  
pp. S359-S359
Author(s):  
Ji Su KIM ◽  
Munseok CHOI ◽  
Sung Hyeon KIM ◽  
Sung Hoon CHOI ◽  
Chang Moo KANG
BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yunqiang Cai ◽  
He Cai ◽  
Bing Peng

Abstract Background Laparoscopic pancreaticoduodenectomy (LPD) is gaining popularity in last decade. However, it is still technical challenging to perform LPD for patients with large periampullary tumors. Methods From January 2019 to January 2020, 13 cases of LPD were performed via anterior approach. Data were collected prospectively in terms of demographic characteristics (age, gender, body mass index, pathological diagnosis and tumor size), intra-operative variables (operative time, estimated blood loss, transfusion), and post-operative variables (time for oral intake, post-operative hospital stay, and complications). Results There were five male patients and eight female patients included in this study. The median age of these patients was 52.7 ± 14.5 years. The median size of tumors was 7.2 ± 2.9 cm. One patient converted to open surgery because of uncontrollable hemorrhage. The median operative time was 356 ± 47 min. The median estimated blood loss was 325 ± 216 ml. The mean post-operative hospital stay was 12.4 ± 1.9 days. One patient suffered from grade B pancreatic fistula. One patient suffered from delayed gastric emptying which was cured by conservative therapy. 90-day mortality was zero. Conclusions Laparoscopic pancreaticoduodenectomy via anterior approach is safe and feasible for patients with large periampullary tumors. Its oncological benefit requires further investigation.


2019 ◽  
Vol 34 (3) ◽  
pp. 1343-1352 ◽  
Author(s):  
Ki Byung Song ◽  
Song Cheol Kim ◽  
Woohyung Lee ◽  
Dae Wook Hwang ◽  
Jae Hoon Lee ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Haipeng Meng ◽  
Song Wang ◽  
Jinchao Liu ◽  
Xu Zhao ◽  
Zhen Rong ◽  
...  

2015 ◽  
Vol 220 (5) ◽  
pp. 831-838 ◽  
Author(s):  
Safi Dokmak ◽  
Fadhel Samir Ftériche ◽  
Béatrice Aussilhou ◽  
Yacine Bensafta ◽  
Philippe Lévy ◽  
...  

BMC Surgery ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Runwen Liu ◽  
Yunqiang Cai ◽  
He Cai ◽  
Yajia Lan ◽  
Lingwei Meng ◽  
...  

Abstract Background With the recent emerge of dynamic prediction model on the use of diabetes, cardiovascular diseases and renal failure, and its advantage of providing timely predicted results according to the fluctuation of the condition of the patients, we aim to develop a dynamic prediction model with its corresponding risk assessment chart for clinically relevant postoperative pancreatic fistula after laparoscopic pancreaticoduodenectomy by combining baseline factors and postoperative time-relevant drainage fluid amylase level and C-reactive protein-to-albumin ratio. Methods We collected data of 251 patients undergoing LPD at West China Hospital of Sichuan University from January 2016 to April 2019. We extracted preoperative and intraoperative baseline factors and time-window of postoperative drainage fluid amylase and C-reactive protein-to-albumin ratio relevant to clinically relevant pancreatic fistula by performing univariate and multivariate analyses, developing a time-relevant logistic model with the evaluation of its discrimination ability. We also established a risk assessment chart in each time-point. Results The proportion of the patients who developed clinically relevant postoperative pancreatic fistula after laparoscopic pancreaticoduodenectomy was 7.6% (19/251); preoperative albumin and creatine levels, as well as drainage fluid amylase and C-reactive protein-to-albumin ratio on postoperative days 2, 3, and 5, were the independent risk factors for clinically relevant postoperative pancreatic fistula. The cut-off points of the prediction value of each time-relevant logistic model were 14.0% (sensitivity: 81.9%, specificity: 86.5%), 8.3% (sensitivity: 85.7%, specificity: 79.1%), and 7.4% (sensitivity: 76.9%, specificity: 85.9%) on postoperative days 2, 3, and 5, respectively, the area under the receiver operating characteristic curve was 0.866 (95% CI 0.737–0.996), 0.896 (95% CI 0.814–0.978), and 0.888 (95% CI 0.806–0.971), respectively. Conclusions The dynamic prediction model for clinically relevant postoperative pancreatic fistula has a good to very good discriminative ability and predictive accuracy. Patients whose predictive values were above 14.0%, 8.3%, and 7.5% on postoperative days 2, 3, and 5 would be very likely to develop clinically relevant postoperative pancreatic fistula after laparoscopic pancreaticoduodenectomy.


HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S75
Author(s):  
S. Dokmak ◽  
B. Aussilhou ◽  
F.S. Ftériche ◽  
O. Soubrane ◽  
A. Sauvanet

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