scholarly journals Correlation between Hemispherectomy and Hemiparesis in Drug Resistant Epilepsy

2021 ◽  
Vol 11 (1) ◽  
pp. 32-38
Author(s):  
Al Khateeb Mashael ◽  
Haris Maryam ◽  
Razack Raidah Ayesha

Background and Purpose: Refractory epilepsy is when seizures are unresponsive to two or more medications. Hemispherectomy, one of the treatment options, is the complete removal or functional disconnection of a cerebral hemisphere. Hemiparesis, a symptom of epilepsy, is defined as weakness of one side of the body. Patients with refractory epilepsy, who experience extreme seizure frequency, are subjected to hemispherectomy. This study focuses on finding the correlation between hemispherectomy and hemiparesis, discovering a pattern in its severity levels before and after surgery.Methods: Data was collected from 59 epileptic patients suffering from refractory epilepsy, who underwent hemispherectomy, at the King Faisal Specialist Hospital and Research Centre, from 1998 to 2014. Each patient was monitored over a period of 1-year post-surgery. In this study, we wanted to further explore the correlation between hemispherectomy and hemiparesis.Results: Upon analyzing the sample size, the level of hemiparesis pre and post hemispherectomy remained the same for 32 patients, of which 13 patients had mild levels pre-surgery and 19 patients had moderate to severe levels pre-surgery. However, 20 of the patients who had moderate to severe levels of hemiparesis before the surgery had either no hemiparesis or a mild level after surgery, which signified an improvement in their severity level. On the other hand, seven of the patients went from having no hemiparesis before the surgery to having moderate or severe levels of hemiparesis post-surgery. Although the results were clinically significant, they were not statistically significant as the p-value obtained was 0.31.Conclusions: After analyzing the results, it can be concluded that hemispherectomy does decrease the severity of hemiparesis in an epileptic patient, thereby improving his/her quality of life drastically.

2020 ◽  
Vol 5 (2) ◽  
pp. 100-107
Author(s):  
Reny Sulistyowati ◽  
Syam�ani Syam�ani

Stress is an individual's adaptive response to various external pressures or demands and produces a variety of disorders including physical, emotional and behavioral disorders. Final year students often experience feelings of stress so that it can interfere with concentration to attend lectures and can even hamper completing education in a timely manner. There are several ways of managing stress, one of which is using aromatherapy. Aromatherapy is a non-pharmacological therapy, which is a type of therapy that applies direct body contact and has a therapeutic effect that combines physiological effects, caused by massage on the body, with psychological effects, which are derived from essential oils. The general purpose of the study is to analyze the effect of aromatherapy on blood pressure and stress levels by using the Kessler Psychological Distress Scale in final semester students. The research method used a quasi-experimental design with a pretest-posttest control group design approach, in 28 intervention groups, namely respondents who were given lavender aromatherapy massage and 28 respondents in the control group. The univariate analysis was conducted to show frequency distribution and bivariate analysis was conducted by independent sample T-test and dependent sample T-test. The results showed that there were significant differences in systolic blood pressure before and after the intervention in the intervention and the control group with a p-value of 0.01 < 0.05. Whereas the stress level variable found that there is no difference in stress levels in the intervention and the control group before and after the intervention with p-value 0.169> 0.05.


2019 ◽  
Vol 125 ◽  
pp. 05005
Author(s):  
Cahyaning Puji Astuti ◽  
Melyana Nurul Widyawati ◽  
Suryono Suryono

Pregnancy is a period of both hormonal and non-hormonal overall change in the body. Emotional instability is commonly experienced by women during this period. However, this somewhat complex issue is often not addressed optimally. Pharmacological therapies using CPZ and lithium are often administered, but they have effects for the body. Therefore, there is a need to administer non-pharmacological therapy that has minimum side effects. This research aims to increase the healthy energy within the body using Pranic Healing, which is measured by the Bio-Well GDV camera. This research employed the pretest-posttest method on two groups (treatment and control) using the Randomized Controlled Trial design. Pranic Healing therapy was performed for 30 minutes once a week for 3 weeks, while GDV measurement was performed once a week for 4 weeks. Paired t-test results for Pranic Healing on emotional pressure showed p-value of 0.0001 (<0.05) for posttest2 and p-value of 0.005 (<0.05) for posttest3. Meanwhile, the control group did not indicate any changes in emotional stress both before and after treatment. It is found that Pranic Healing as measured using a bio-well GDV camera is capable of improving health energy within the body by relieving emotional stress experienced in trimester III primigravida.


2014 ◽  
Vol 3 (2) ◽  
pp. 11-15
Author(s):  
Sidra Zahid ◽  
Ghazala Noor Nizami

OBJECTIVE To find out the effectiveness of neural mobilization and stretching exercise for the management of sciatica BACKGROUND Sciatica is described as pain, radiating to the leg below the knee joint and caused by irritation of the sciatic nerve or nerve trunk. There are many treatment options for the management of sciatica, including stretching exercise and neural mobilization. MATERIAL AND METHODS This study was a Randomized Controlled Trial. 94 patients from physical therapy OPD of tertiary care hospitals, were participated in this study. Hence, 47 patients were randomly allocated into each group A and B. Before and after the nine treatment sessions, both groups were assessed with VAS, SLR ROM and Quebec back pain disability scale. In group A, neural mobilization with conventional therapy (heat and TENS) was applied, while stretching exercise with same conventional therapy was applied to group B. RESULTS It was observed that both treatments were helpful in reducing the symptoms. The analysis showed significant improvement (p-value <0.05) in the SLR to 60.851o±6.86oand Quebec score to 23.617±3.125, after the stretching exercise. Hence, both treatments were equally effective in reducing pain (p-value >0.05). CONCLUSION Stretching exercise is more effective in the improvement of SLR and disability. Furthermore, both techniques are helpful in the management of pain. KEY WORDS Sciatica, Stretching, Neural Mobilization, Straight Leg Raising, Visual Analogue Scale, TENS.


2019 ◽  
Vol 3 (1) ◽  
pp. 14
Author(s):  
Sonhaji Sonhaji ◽  
Roland Lekatompessy

The result of statistical analysis obtained data on the average blood pressure inthe left group before being given the intervention of 173,76/96,41 while after being given the intervention of 170,29/93,82. On the singing group before being given intervention, the average of blood pressure of 153,06/87,41 and after being given intervention tobe 168/87. Camparative test results in both groups between before and after ihe invention were obtained p – value = 0,00 (p- value p < 0,05). Conclusion was spiritual emotional freedom techneque (SEFT) is more effective than singing to reduce the blood pressurenof the elderly with hypertension in social service home, Pucang Gading, Semarang. One of the body system disorders that is often experienced by the elderly. Namely the cardiovascular system such as hypertension. Hypertension of elderly can caused bad condition such as heartdiscase, stroke and kidney failure, there fore, intervention is needed to maintain blood pressure within normal himits.


2020 ◽  
Vol 2 (2) ◽  
pp. 211-218
Author(s):  
Diah Evawanna Anuhgera ◽  
Wilda Wahyuni Siregar ◽  
Nikmah Jalilah Ritonga ◽  
Desikawali Pardede

Abstract Labor is always synonymous with the experience of pain and fear felt by mother. SSBM stimulates the body release endorphins which are having natural pain killing propoerties and reducing anxiety levels. This study aimed to determine the effect of slow stroke back massage (SSBM) on reduction of labor pain and anxiety during first stage of labor. A quasi-experimental study with purposive non-probability sampling techniwue is used for the people. Study was conducted on 36 samples (18 in experimental group anda 18 in control group). A structured interview schedule, albor assesment performa, numerical pain rating scale and DASS(Depresssion, Anxiety and Stress Scales) were used for data collection and the data were analyzed by paired and unpaired t test. There were statistically significant differences of anxiety and pain levels before and after intervention in the experiment and control group with p value 0.00.Result confirmed that SSBM is significantly effective in reducing labor pain and anxiety level during first stage of labor. Abstract Labor is always synonymous with the experience of pain and fear felt by mother. SSBM stimulates the body release endorphins which are having natural pain killing propoerties and reducing anxiety levels. This study aimed to determine the effect of slow stroke back massage (SSBM) on reduction of labor pain and anxiety during first stage of labor. A quasi-experimental study with purposive non-probability sampling techniwue is used for the people. Study was conducted on 36 samples (18 in experimental group anda 18 in control group). A structured interview schedule, albor assesment performa, numerical pain rating scale and DASS(Depresssion, Anxiety and Stress Scales) were used for data collection and the data were analyzed by paired and unpaired t test. There were statistically significant differences of anxiety and pain levels before and after intervention in the experiment and control group with p value 0.00.Result confirmed that SSBM is significantly effective in reducing labor pain and anxiety level during first stage of labor.


Author(s):  
Indah Pramita ◽  
Agus Donny Susanto

Elderly is an advanced stage process that decreases the ability and function of the body. One of the declines that occur in the elderly is the musculoskeletal system in which it is very influential on balance. Square stepping exercise is one type of exercise that can be used in addition to increasing the strength of the musculoskeletal system, this exercise is also able to improve the visual ability. By increasing the ability of the musculoskeletal system, coupled with the visual ability is expected to improve balance in the elderly and reduce the risk of falling. The purpose of this research is to know the effect of Square stepping exercise on increasing the dynamic balance of elderly.This experimental study used a pre test and post test design. The sampling was done at Panti Wreda Sejahtera Denpasar. Elderly as many as 27 people who fit the criteria serve as a sample. The dynamic balance is evaluated by using the Time Up and Go test (TUG test) before and after the exercise. This study was conducted 3x a week for 4 weeks.Effect analysis test using Paired Sample test obtained p value = 0.001 with a balance increase of 27.92%. The conclusion of research that Giving Square Stepping Exercise can improve dynamic balance in elderly.Keywords: Elderly, Square Stepping Exercixe, Balance


2013 ◽  
Author(s):  
Xundou Li ◽  
Mindi Zhao ◽  
Menglin Li ◽  
Lulu Jia ◽  
Youhe Gao

Biomarker is the measurable change associated with a physiological or pathophysiological process. Unlike blood which has mechanisms to keep the internal environment homeostatic, urine is more likely to reflect changes of the body. In other words, urine is likely to be a better biomarker source than blood. However, the urinary proteome are affected by many factors. In this study, the effects of three commonly used diuretics (furosemide, hydrochlorothiazide and spirolactone ) on the urinary proteome were analyzed in rats. Urine samples were collected before and after the intragastric administration of diuretics at therapeutic doses and analyzed using LC-MS/MS. Based on quantification by Progenesis LC-MS software, there are 7, 5 and 2 proteins with the p value ≤0.05, a fold change ≥2, a spectral count ≥5 and FDR ≤1%, respectively. Most their human orthologs were considered to be stable in the healthy human urinary proteome. 10 of the 14 proteins have been reported as disease biomarkers in previous studies. So the effects of diuretics should be given more attention in future urinary protein biomarkers studies. The effects of diuretics on urinary proteome are different which can provide clues to elucidate the mechanisms of the diuretics.


Jurnal Ners ◽  
2017 ◽  
Vol 1 (1) ◽  
Author(s):  
YENNY SAFITRI

One of the therapy that can reduce anxiety is Benson relaxation. This therapy will inhibit the activity of the sympathetic nervous which will reduce oxygen consumption by the body and then the muscles are relaxed, causing a feeling of calm and comfortable. This study uses a quasi-experimental research design, with the approach of pretest-posttest design with control group, involving the control group in addition to the experimental group. With the use of accidental sampling technique then set 30 as sample. The measurement of anxiety exerts performed before and after treatment using Ratting Hamilton Anxiety Scale (HARS) the intervention is given for 1 week. The results of statistical tests using independent t test obtained p-value = 0.000 significant p-value <0.05 then Ho is rejected, which means that the influence of Benson relaxation on the level of anxiety in patients with cervical cancer before and after Benson relaxation therapy.


Author(s):  
Parviz Shojaei ◽  
Mehran Ghahramani ◽  
Sirous Farsi

Objective: Obesity is a chronic disease characterized by an excessive mass of adipose tissue in the body. The present study aimed to investigate the relationship between different genotypes of VEGF gene and changes in aerobic capacity following aerobic exercise in obese women. Materials and Methods: In this study, 23 inactive women aged 34 to 43 years with BMI 30 and 35 were purposefully selected and participated in eight weeks of aerobic exercise including 4 sessions per week and 30 minutes per session with an intensity of 55 to 75% of maximum heart rate. Before and after the training period, aerobic power (VO2max) was measured by the modified Bruce test. Saliva Sample was collected at 12 hours of fasting to measure VEGF genotypes. To compare aerobic capacity between different genotypes, since we had three genotypes GG, CG, and CC, one-way analysis of variance was used. Results: Although the mean amount of aerobic power changes of GG genotype was somewhat higher after eight weeks of aerobic training than the other two genotypes, this difference was not significant. (P-value= 0.663, P-value= 0.873 and P-value= 0.173, respectively). Conclusion: Eight weeks of aerobic training leads to increased aerobic capacity in obese women and increased VEGF plays a role, but there is not seemingly a difference between different VEGF genotypes for these changes. In any case, since this study was conducted for the first time, we need more studies to draw a more accurate conclusion.


2016 ◽  
Vol 3 (2) ◽  
pp. 131-135
Author(s):  
Laily Wahidatul Oktavia ◽  
Maria Ulfa

The consumption of dark chocolate on the second day of mother post section caesarea canreduce anxiety, since the asetosal substance can stimulate the limbic system of hypothalamus to suppressthe anxiety. Method: The research design was a Quasy experimental. The research sample was 8mother post sectio caesarea in Ngudi Waluyo Hospital Cempaka Wlingi at August 14th, up to September14th, 2015, it was chosen using accidental sampling. The data analyzed by Wilcoxon rank test. Result:showed a decrease in the percentage of anxiety scale before and after eating dark chocolate in whichthe anxiety scale of 87.5% to 20%. Based on statistical analysis showed Wlicoxon Signed Rank Test pvalue = 0,008, so p value = 0.008 < = 0.05. Discussion: relaxed condition was needed in the processof recovery condition after partum mothers, especially post surgery. Psychological factors like familysupport also needed to optimize all of the action taken.


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