scholarly journals New Classification of Focal Cortical Dysplasia: Application to Practical Diagnosis

1970 ◽  
Vol 2 (2) ◽  
pp. 38-42 ◽  
Author(s):  
Yoon-Sung Bae ◽  
Hoon-Chul Kang ◽  
Heung Dong Kim ◽  
Se Hoon Kim
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
New Classification

scholarly journals Neuropathology of Temporal Lobe Epilepsy

2012 ◽  
Vol 2012 ◽  
pp. 1-13 ◽  
Author(s):  
Fahd Al Sufiani ◽  
Lee Cyn Ang
Keyword(s):  
Temporal Lobe Epilepsy ◽  
Temporal Lobe ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Wide Range ◽  
Pathologic Findings ◽  
Pathologic Lesions ◽  
Recent Classification ◽  
Associated Tumors

Pathologic findings in surgical resections from patients with temporal lobe epilepsy include a wide range of diagnostic possibilities that can be categorized into different groups on the basis of etiology. This paper outlines the various pathologic entities described in temporal lobe epilepsy, including some newly recognized epilepsy-associated tumors, and briefly touch on the recent classification of focal cortical dysplasia. This classification takes into account coexistent pathologic lesions in focal cortical dysplasia.

Is there evidence for clinical differences related to the new classification of temporal lobe cortical dysplasia?

Epilepsia ◽  
2013 ◽  
Vol 54 (5) ◽  
pp. 909-917 ◽  
Author(s):  
Susanne Fauser ◽  
Charles Essang ◽  
Dirk Matthias Altenmüller ◽  
Anke Staack ◽  
Bernhard J. Steinhoff ◽  
...  
Keyword(s):  
Temporal Lobe ◽  
Cortical Dysplasia ◽  
New Classification

scholarly journals Putting the new ILAE classification of focal cortical dysplasia into practice in western China

Seizure ◽  
2017 ◽  
Vol 51 ◽  
pp. 133-138 ◽  
Author(s):  
Cheng Huang ◽  
Heng Zhang ◽  
Xiao-sa Chi ◽  
Ni Chen ◽  
Jing Gong ◽  
...  
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Western China ◽  
Ilae Classification

Surgical treatment of intractable epilepsy associated with focal cortical dysplasia

2008 ◽  
Vol 25 (3) ◽  
pp. E6 ◽  
Author(s):  
Roberto Jose Diaz ◽  
Elisabeth M. S. Sherman ◽  
Walter J. Hader
Keyword(s):  
Refractory Epilepsy ◽  
Functional Neuroimaging ◽  
Focal Cortical Dysplasia ◽  
Intractable Epilepsy ◽  
Cortical Dysplasia ◽  
Complete Resection ◽  
Epileptogenic Zone ◽  
Malformations Of Cortical Development ◽  
Cortical Dysplasias

Focal cortical dysplasias (FCDs) are congenital malformations of cortical development that are a frequent cause of refractory epilepsy in both children and adults. With advances in structural and functional neuroimaging, these lesions are increasingly being identified as a cause of intractable epilepsy in patients undergoing surgical management for intractable epilepsy. Comprehensive histological classification of FCDs with the establishment of uniform terminology and reproducible pathological features has aided in our understanding of FCDs as an epilepsy substrate. Complete resection of FCDs and the associated epileptogenic zone can result in a good surgical outcome in the majority of patients.

Clinical Application of Experimental Cortical Dysplasia in Rats

2004 ◽  
Vol 19 (3) ◽  
pp. 351-356
Author(s):  
Tatsuya Tanaka ◽  
Hiroshige Tsuda ◽  
Kiyotaka Hashizume ◽  
Juro Sakurai ◽  
Akira Hodozuka ◽  
...  
Keyword(s):  
Surgical Outcome ◽  
Focal Cortical Dysplasia ◽  
Experimental Studies ◽  
Intractable Epilepsy ◽  
Cortical Dysplasia ◽  
Surgical Results ◽  
Postoperative Results ◽  
Epileptiform Discharges ◽  
Pathologic Classification

This report details clinical and experimental studies of focal cortical dysplasia. The first part deals with 14 surgical cases of children with intractable epilepsy. At surgery, intraoperative electrocorticography was performed to localize the epileptic foci under neuroleptanalgesia. Thirteen patients showed epileptiform discharges on this preresection electrocorticography. All foci in noneloquent areas were resected. Patients who had undergone total lesionectomy with complete focus resection showed the most favorable postoperative results. However, the positive correlation between the intraoperative electrocorticographic findings and the pathologic classification of cortical dysplasia was not found in the present study. Nine patients have been seizure free with reduced medication and two patients have achieved worthwhile improvement. We conclude that intraoperative electrocorticography can improve the surgical outcome for intractable epilepsy by localizing epileptic foci for resection. The second part describes a kainic acid—induced experimental model of focal cortical dysplasia, which demonstrated not only the epileptic properties of the dysplasia but also the perilesional epileptogenicity. The findings supported the surgical results for the patients with focal cortical dysplasia. ( J Child Neurol 2005;20:351—356).

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