scholarly journals First National Congress on Alternatives to Animal Testing and post-congress workshops in India

ALTEX ◽  
2018 ◽  
pp. 258-260 ◽  
Author(s):  
Mohammad Akbarsha
Keyword(s):  
Animal Testing ◽  
Alternatives To Animal Testing ◽  
National Congress

Alternatives to Animal Testing in the Quality Control of Immunobiologicals: Current Status and Future Prospects

1994 ◽  
Vol 22 (6) ◽  
pp. 420-434
Author(s):  
Coenraad F.M. Hendriksen ◽  
Bernward Garthoff ◽  
Henrik Aggerbeck ◽  
Lucas Bruckner ◽  
Peter Castle ◽  
...  
Keyword(s):  
Quality Control ◽  
Current Status ◽  
Future Prospects ◽  
Animal Testing ◽  
Alternatives To Animal Testing

Research on the development of alternatives to animal testing for pharmaceutical products and international standardisation

Impact ◽  
2021 ◽  
Vol 2021 (8) ◽  
pp. 44-45
Author(s):  
Hajime Kojima
Keyword(s):  
Research Group ◽  
Pharmaceutical Products ◽  
In Vitro Assays ◽  
Animal Testing ◽  
3 Dimensional ◽  
Alternatives To Animal Testing ◽  
Gene Assay ◽  
Innovative Work ◽  
Regulatory Acceptance

Scientists are working to develop new and innovative alternatives to animal testing that don't rely on the use of animals. Takao Ashikaga, Hajime Kojima and Yoko Hirabayashi are part of JaCVAM which works to promote the use of alternatives to animal testing. The goal is to replace, reduce or refine (3Rs) the use of animal under International harmonization. Hirabayashi is also the representative of a research group that is funded by the AMED and the representative of a research group funded by the MHLW. A challenge the researchers are facing in their quest to ensure the welfare of experimental animals and also ensure the safety of various pharmaceutical and chemicals is the lack of biomarkers to more accurately predict toxicity for regulatory acceptance. This means that without animal testing more costly and complex non-animal methods are required and presents a barrier to the adoption of non-animal methods for international standerisation. As such, there is a need to develop an easy way to obtain a lot of information. Hirabayashi and the team are working on the development of AI that can be used to evaluate the safety of different compounds. The researchers are developing in vitro assays such as ordinary 2-dimensional culture, 3-dimensional culture including organoids or spheroids, reporter gene assay and organ-on-a chip; and in silico assays such as computer toxicology using QSAR and Read Across. The researchers hope that their innovative work will contribute to the 3Rs, benefiting animal welfare for regulatory use.

scholarly journals A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Genotoxicity. A COLIPA analysis

2010 ◽  
Vol 57 (2-3) ◽  
pp. 315-324 ◽  
Author(s):  
Stefan Pfuhler ◽  
Annette Kirst ◽  
Marilyn Aardema ◽  
Norbert Banduhn ◽  
Carsten Goebel ◽  
...  
Keyword(s):  
Safety Assessment ◽  
Animal Testing ◽  
Tiered Approach ◽  
Alternatives To Animal Testing

scholarly journals Alternatives to animal testing: A review

2015 ◽  
Vol 23 (3) ◽  
pp. 223-229 ◽  
Author(s):  
Sonali K. Doke ◽  
Shashikant C. Dhawale
Keyword(s):  
Animal Testing ◽  
Alternatives To Animal Testing

scholarly journals A tiered approach to the use of alternatives to animal testing for the safety assessment of cosmetics: Skin irritation

2009 ◽  
Vol 54 (2) ◽  
pp. 188-196 ◽  
Author(s):  
Martin Macfarlane ◽  
Penny Jones ◽  
Carsten Goebel ◽  
Eric Dufour ◽  
Joanna Rowland ◽  
...  
Keyword(s):  
Safety Assessment ◽  
Skin Irritation ◽  
Animal Testing ◽  
Tiered Approach ◽  
Alternatives To Animal Testing
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