scholarly journals A New Strategy of Validities’ Computation for Multimodel Approach: Experimental Validation

2017 ◽  
Vol 8 (7) ◽  
Author(s):  
Abdennacer BEN ◽  
Samia TALMOUDI ◽  
Moufida LAHMARI
Keyword(s):  
Experimental Validation ◽  
New Strategy

scholarly journals IDSSR: An Efficient Pipeline for Identifying Polymorphic Microsatellites from a Single Genome Sequence

2019 ◽  
Vol 20 (14) ◽  
pp. 3497 ◽  
Author(s):  
Xuan-Min Guang ◽  
Jin-Quan Xia ◽  
Jian-Qing Lin ◽  
Jun Yu ◽  
Qiu-Hong Wan ◽  
...  
Keyword(s):  
Genome Sequence ◽  
Experimental Validation ◽  
High Reliability ◽  
Molecular Ecology ◽  
Polymorphic Ssrs ◽  
Screening Experiments ◽  
Single Genome ◽  
New Strategy ◽  
Nucleotide Insertions ◽  
Single Genome Sequence

Simple sequence repeats (SSRs) are known as microsatellites, and consist of tandem 1–6-base motifs. They have become one of the most popular molecular markers, and are widely used in molecular ecology, conservation biology, molecular breeding, and many other fields. Previously reported methods identify monomorphic and polymorphic SSRs and determine the polymorphic SSRs via experimental validation, which is potentially time-consuming and costly. Herein, we present a new strategy named insertion/deletion (INDEL) SSR (IDSSR) to identify polymorphic SSRs by integrating SSRs with nucleotide insertions/deletions (INDEL) solely based on a single genome sequence and the sequenced pair-end reads. These INDEL indexes and polymorphic SSRs were identified, as well as the number of repeats, repeat motifs, chromosome location, annealing temperature, and primer sequences, enabling future experimental approaches to determine the correctness and polymorphism. Experimental validation with the giant panda demonstrated that our method has high reliability and stability. The efficient SSR pipeline would help researchers obtain high-quality genetic markers for plants and animals of interest, save labor, and reduce costly marker-screening experiments. IDSSR is freely available at https://github.com/Allsummerking/IDSSR.

A new strategy for prenatal diagnosis in a sporadic haemophilia B family

Haemophilia ◽  
2001 ◽  
Vol 7 (4) ◽  
pp. 416-418 ◽  
Author(s):  
M. Acquila ◽  
F. Bottini ◽  
A. Valetto ◽  
D. Caprino ◽  
P. G. Mori ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Haemophilia B ◽  
New Strategy

Guidelines Bring New Strategy in Low-Risk AF

2012 ◽  
Vol 45 (15) ◽  
pp. 12-13
Author(s):  
BRUCE JANCIN
Keyword(s):  
Low Risk ◽  
New Strategy

New Strategy for the Synthesis of 2-Deoxy-C-aryl-nucleoside Frameworks

2006 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
S.M. Mahalingam ◽  
S. Vijayasaradhi ◽  
I.S. Aidhen
Keyword(s):  
New Strategy

Experimental validation of the predicted TGR5 binding mode model

2015 ◽  
Vol 53 (01) ◽  
Author(s):  
L Spomer ◽  
CGW Gertzen ◽  
D Häussinger ◽  
H Gohlke ◽  
V Keitel
Keyword(s):  
Experimental Validation ◽  
Binding Mode

New strategy to search lead compounds with unique structures from plants

Planta Medica ◽  
2015 ◽  
Vol 81 (11) ◽  
Author(s):  
T Villani ◽  
K Gustafson ◽  
J Zhen ◽  
JE Simon ◽  
Q Wu
Keyword(s):  
Lead Compounds ◽  
New Strategy

Latin America in Difficult Search of Its Way

2004 ◽  
pp. 107-117
Author(s):  
Z. Romanova
Keyword(s):  
Latin America ◽  
Demographic Structure ◽  
Financial Problems ◽  
Strategy Of Development ◽  
Small Countries ◽  
New Strategy

The article is devoted to the analysis of economic and financial problems and contradictions accumulated in Latin America under conditions of globalization and market liberation. The originated unfavorable changes gave rise to the need of policy correction in big and small countries. The author analyses a new strategy of development adequate for Latin America with its specific geopolitical situation, demographic structure and history.

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