scholarly journals THE STUDY OF GENDER AND AGE FEATURES OF POSTURAL DISORDERS IN HORIZONTAL PLANE IN CHILDREN AND ADOLESCENTS ACCORDING TO COMPUTER OPTICAL TOPOGRAPHY

2012 ◽  
pp. 38-48
Author(s):  
Vladimir Sarnadsky ◽  
Keyword(s):  
Children And Adolescents ◽  
Horizontal Plane ◽  
Gender And Age ◽  
Optical Topography ◽  
Age Features ◽  
Postural Disorders

Risperidone-treated Children and Adolescents with Behavioral Disorders: Do Drug Dose and Patients’ Gender and Age Relate to Drug and Metabolite Plasma Levels?

2017 ◽  
Vol 41 (S1) ◽  
pp. S104-S104
Author(s):  
D. Piacentino ◽  
M. Grözinger ◽  
A. Saria ◽  
F. Scolati ◽  
D. Arcangeli ◽  
...  
Keyword(s):  
Regression Analysis ◽  
Children And Adolescents ◽  
Behavioral Disorders ◽  
Plasma Levels ◽  
Linear Models ◽  
Parent Drug ◽  
Drug Dose ◽  
Cut Elimination ◽  
Younger Patients ◽  
Gender And Age

IntroductionBehavioral disorders, such as conduct disorder, influence choice of treatment and its outcome. Less is known about other variables that may have an influence.Objectives/AimsWe aimed to measure the parent drug and metabolite plasma levels in risperidone-treated children and adolescents with behavioral disorders and investigate the role of drug dose and patients’ gender and age.MethodsWe recruited 115 children/adolescents with DSM-5 behavioral disorders (females = 24; age range: 5–18 years) at the Departments of Psychiatry of the Hospitals of Bolzano, Italy, and Innsbruck, Austria. We measured risperidone and its metabolite 9-hydroxyrisperidone plasma levels and the parent drug-to-metabolite ratio in the plasma of all patients by using LC-MS/MS. A subsample of 15 patients had their risperidone doses measured daily. We compared risperidone and 9-hydroxyrisperidone plasma levels, as well as risperidone/9-hydroxyrisperidone ratio, in males vs. females and in younger (≤ 14 years) vs. older (15–18 years) patients by using Mann-Whitney U test. We fitted linear models for the variables “age” and “daily risperidone dose” by using log-transformation, regression analysis and applying the R2 statistic.ResultsFemales had significantly higher median 9-hydroxyrisperidone plasma levels (P = 0.000). Younger patients had a slightly lower median risperidone/9-hydroxyrisperidone ratio (P = 0.052). At the regression analysis, daily risperidone doses and metabolite, rather than parent drug–plasma levels were correlated (R2 = 0.35).ConclusionsGender is significantly associated with plasma levels, with females being slower metabolizers than males. Concerning age, younger patients seem to be rapid metabolizers, possibly due to a higher activity of CYP2D6. R2 suggests a clear-cut elimination of the metabolite.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Analysis of energy value of diets depending on diet in children and adolescents with overweight and obesity

2021 ◽  
pp. 58-61
Author(s):  
L. Yu. Volkova ◽  
S. V. Orlova
Keyword(s):  
Health Care ◽  
Children And Adolescents ◽  
Negative Relationship ◽  
Overweight And Obesity ◽  
Calorie Intake ◽  
Caloric Content ◽  
Calorie Content ◽  
Modern Health Care ◽  
Urgent Task ◽  
Gender And Age

The study of diet as a factor influencing the formation of an exogenous constitutional form of obesity in children and adolescents is an urgent task of modern health care. The distribution of energy by meals has a significant impact on the degree of overweight and the severity of obesity. In the course of the study, a weak positive correlation (r = 0.26) was revealed between the proportion of dinner in terms of calorie content and the degree of overweight: the higher the proportion of dinner in the overall structure of the caloric content of the diet, the higher the degree of obesity in a child. With regard to breakfast, an inverse negative relationship was revealed (r = -0.27): the lower the proportion of breakfast in terms of calorie content, the higher the BMI value by gender and age. The high proportion of calories in the evening meals (afternoon snack and dinner) is more important for the degree of obesity in boys (r = 0.40) than in girls (r = 0.34). The older the child, the stronger the correspondence between excess calorie intake in evening meals and the degree of excess weight (at 8-10 years old r = 0.26; at 11-13 years old r = 0.31; at 14-18 years old r = 0.48).

THE FEATURES OF FORMATION SOMATIC PATHOLOGIES AT INFLUENCE OF LOCAL VIBRATION IN THE CONDITIONS OF METALLURGICAL MANUFACTURE

2021 ◽  
Author(s):  
E.L. Bazarova ◽  
◽  
I.S. Osherov ◽  
N.A. Roslaya ◽  
Keyword(s):  
Working Conditions ◽  
Negative Impact ◽  
Age Groups ◽  
Average Degree ◽  
Production Environment ◽  
Local Vibration ◽  
Relative Risks ◽  
Gender And Age ◽  
Age Features ◽  
The Impact

Abstract: Relevance. Local vibration is a significant factor in the production environment of metallurgical production, which affects health and efficiency. The aim of the study is to identify the exposure, gender and age features of the formation of general somatic morbidity associated with the impact of local vibration in the production of titanium alloys. Scope and methods. The prevalence of general somatic pathology was compared in 2596 workers who have contact with local vibration, with varying degrees of harmfulness of working conditions, and non-exposed persons according to the results of periodic medical examination using the methodology of occupational risk analysis of the Research Institute of Occupational Medicine. academician N. F. Izmerov. Results. At comparison of prevalence of a somatic pathology at workers in contact to local vibration to not exhibited persons according to medical inspection, and at different degree of harm of working conditions, are revealed the raised risks of formation of diseases nervous, kostno-muscular, endocrine systems, respiratory organs, digestion, an ear, a skin, an arterial hypertensia, the mental frustration, the raised weight of a body, gynecologic diseases with a tendency of growth of the majority of them at the big levels of vibration, more often at small, less often - average degree of communication with working conditions. The frequency of pathology in exposed workers was higher in all age groups. Average degree of communication with working conditions of a gynecologic pathology at the age of 18-25 years was marked. At men frequency of a pathology of respiratory organs, digestion is revealed authentically big, than at women; an ear; skin at the big relative risks 1,2-1,3, of the raised arterial pressure and hyperglycemia. Conclusion. A higher frequency of visceral pathology of a number of body systems under the influence of local vibration of high levels may justify the need to develop differentiated preventive programs to minimize its negative impact, taking into account the identified features in sex and age groups.

Gender and age features frequencies of COVID-19

2021 ◽  
Vol 29 (Special Issue) ◽  
Author(s):  
E. M. Osmanov ◽  
◽  
R. R. Manyakov ◽  
L. M. Tuktamysheva ◽  
R. V. Yusupov ◽  
...  
Keyword(s):  
Gender And Age ◽  
Age Features
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