Structure-biological Activity Relationship of Analogues of 2-Chlorobenzylidenemalononitrile -A Riot-control Agent

2005 ◽  
Vol 55 (4) ◽  
pp. 447-457 ◽  
Author(s):  
P. K. Gutch ◽  
Pravin Kumar ◽  
M.V.S. Suryanarayana ◽  
R. C. Malhotra
2000 ◽  
Vol 53 (12) ◽  
pp. 909 ◽  
Author(s):  
Yoshikazu Hiraga ◽  
Mariko Ago ◽  
Munetaka Tokumasu ◽  
Ken Kaku ◽  
Katsuo Ohkata

Analogues of hippospongic acid A, which inhibit the gastrulation of sea urchin embryos, were synthesized. From a study on structure—activity relationships, the conjugated carboxylic acid moiety was found to be an essential feature for biological activity.


2014 ◽  
Vol 71 (7) ◽  
pp. 928-936 ◽  
Author(s):  
Benjamin M Nugent ◽  
Ann M Buysse ◽  
Michael R Loso ◽  
Jon M Babcock ◽  
Timothy C Johnson ◽  
...  

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