scholarly journals Post-Hatch Neuron Incorporation in The Zebra Finch Caudomedial Nidopallium (NCM) in Relation to Vocal Learning

2016 ◽  
Author(s):  
Kemal Asik
Keyword(s):  
Zebra Finch ◽  
Vocal Learning ◽  
Caudomedial Nidopallium

scholarly journals Behavior-Linked FoxP2 Regulation Enables Zebra Finch Vocal Learning

2015 ◽  
Vol 35 (7) ◽  
pp. 2885-2894 ◽  
Author(s):  
J. B. Heston ◽  
S. A. White
Keyword(s):  
Zebra Finch ◽  
Vocal Learning

scholarly journals Blocking neuroestrogen synthesis modifies neural representations of learned song without altering vocal imitation accuracy in developing songbirds

2019 ◽  
Author(s):  
Daniel M. Vahaba ◽  
Amelia Hecsh ◽  
Luke Remage-Healey
Keyword(s):  
Memory Consolidation ◽  
Temporal Cortex ◽  
Vocal Learning ◽  
Song Learning ◽  
Auditory Memory ◽  
Vocal Imitation ◽  
Neural Representations ◽  
Estrogen Synthesis ◽  
Auditory Experience ◽  
Caudomedial Nidopallium

ABSTRACTBirdsong, like human speech, is learned early in life by first memorizing an auditory model. Once memorized, birds compare their own burgeoning vocalizations to their auditory memory, and adjust their song to match the model. While much is known about this latter part of vocal learning, less is known about how initial auditory experiences are formed and consolidated. In both adults and developing songbirds, there is strong evidence suggesting the caudomedial nidopallium (NCM), a higher order auditory forebrain area, is the site of auditory memory consolidation. However, the mechanisms that facilitate this consolidation are poorly understood. One likely mechanism is 17β-estradiol (E2), which is associated with speech-language development and disorders in humans, and is abundant in both mammalian temporal cortex and songbird NCM. Circulating E2 is also elevated during the auditory memory phase, and in NCM immediately after song learning sessions, suggesting it functions to encode recent auditory experience. Therefore, we tested a role for E2 production in auditory memory consolidation during development using a comprehensive set of investigations to ask this question at the level of neuroanatomy, neurophysiology, and behavior. Our results demonstrate that while systemic estrogen synthesis blockade regulates juvenile song production, inhibiting E2 synthesis locally within NCM does not adversely affect song learning outcomes. Surprisingly, early life E2 manipulations in NCM modify the neural representations of birds’ own song and the model tutor song in both NCM and a downstream sensorimotor nucleus (HVC). Further, we show that the capacity to synthesize neuroestrogens remains high throughout development alongside substantial changes in NCM cell density across age. Taken together, these findings suggest that E2 plays a multifaceted role during development, and demonstrate that contrary to prediction, unilateral post-training estrogen synthesis blockade in the auditory cortex does not negatively impact vocal learning. Acute downregulation of neuroestrogens are therefore likely permissive for juvenile auditory memorization, while neuroestrogen synthesis influences communication production and representation in adulthood.

Delta-9-THC exposure during zebra finch sensorimotor vocal learning increases cocaine reinforcement in adulthood

2019 ◽  
Vol 185 ◽  
pp. 172764 ◽  
Author(s):  
Ahmed Aldhafiri ◽  
Julien C. Dodu ◽  
Ali Alalawi ◽  
Nariman Emadzadeh ◽  
Ken Soderstrom
Keyword(s):  
Zebra Finch ◽  
Vocal Learning
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