scholarly journals Oral administration of labetalol might improve not only the blood pressure but also clinical symptoms in Japanese women with gestational hypertension

2014 ◽  
Vol 2 (2) ◽  
pp. 82-87 ◽  
Author(s):  
Ayano Matsuura ◽  
Tamao Yamamoto ◽  
Tomoe Arakawa ◽  
Yoshikatsu Suzuki
Keyword(s):  
Blood Pressure ◽  
Oral Administration ◽  
Clinical Symptoms ◽  
Gestational Hypertension ◽  
Japanese Women

scholarly journals Gestational Hypertension as Risk Factor of Hypertension in Middle-Aged and Older Women

2020 ◽  
Vol 17 (11) ◽  
pp. 4052
Author(s):  
Mariko Watanabe ◽  
Toshimi Sairenchi ◽  
Keiko Nishida ◽  
Koji Uchiyama ◽  
Yasuo Haruyama ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Risk Factor ◽  
Older Women ◽  
Case Control Study ◽  
Gestational Hypertension ◽  
Japanese Women ◽  
Middle Aged ◽  
Antihypertensive Medications ◽  
And Child Health ◽  
Control Study

The association of gestational hypertension (GH) with future hypertension in Japanese women is unclear. Hence, this study aimed to examine the association between GH and the risk of future hypertension in middle-aged-to-older Japanese women. A case-control study was performed, including 62 hypertensive women (case) and 75 nonhypertensive women (control). GH during the first pregnancy was diagnosed on the basis of the Maternal and Child Health Handbook record. Hypertensive women were recruited from outpatients in the hospital and residents who completed an annual health check-up in a community. Hypertension was defined as blood pressure with systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg, or taking antihypertensive medications. The average age (SD) of the cases and controls at the time of recruitment was 63.1 (8.4) and 57.7 (9.4), respectively. The multivariable-adjusted odds ratio of GH for hypertension in middle-aged-to-older women was 4.2 (95% confidence interval, 1.0–17.5) after adjustment for potential confounding factors such as age and body-mass index (BMI) upon recruitment, prepregnancy BMI, and age at first delivery. In conclusion, GH can be an independent risk factor for future hypertension among Japanese women.

Diagnosing Gestational Hypertension and Preeclampsia With the 24-Hour Mean of Blood Pressure

Hypertension ◽  
1997 ◽  
Vol 30 (6) ◽  
pp. 1531-1537 ◽  
Author(s):  
Ramón C. Hermida ◽  
Diana E. Ayala
Keyword(s):  
Blood Pressure ◽  
Gestational Hypertension

scholarly journals BLOOD CHANGES AND CLINICAL SYMPTOMS FOLLOWING ORAL ADMINISTRATION OF PHOSPHATES

1924 ◽  
Vol 60 (2) ◽  
pp. 311-326
Author(s):  
Harald A. Salvesen ◽  
A.Baird Hastings ◽  
J.F. McIntosh
Keyword(s):  
Oral Administration ◽  
Clinical Symptoms

scholarly journals Progesterone increases blood pressure in spontaneous gestational hypertension in rats

2005 ◽  
Vol 18 (1) ◽  
pp. 36-43 ◽  
Author(s):  
L SHARKEY ◽  
S KIRCHAIN ◽  
S MCCUNE ◽  
G SIMPSON ◽  
E ARCHAMBAULT ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Gestational Hypertension

Renal and cardiac oxidative/nitrosative stress in salt-loaded pregnant rat

2007 ◽  
Vol 293 (4) ◽  
pp. R1657-R1665 ◽  
Author(s):  
Annie Beauséjour ◽  
Véronique Houde ◽  
Karine Bibeau ◽  
Rébecca Gaudet ◽  
Jean St-Louis ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Pressure ◽  
Nitrosative Stress ◽  
Gestational Hypertension ◽  
Sodium Intake ◽  
Pregnant Rats ◽  
High Sodium ◽  
High Sodium Intake ◽  
Arterial Blood ◽  
Cardiac Ventricle

Sodium supplementation given for 1 wk to nonpregnant rats induces changes that are adequate to maintain renal and circulatory homeostasis as well as arterial blood pressure. However, in pregnant rats, proteinuria, fetal growth restriction, and placental oxidative stress are observed. Moreover, the decrease in blood pressure and expansion of circulatory volume, normally associated with pregnancy, are prevented by high-sodium intake. We hypothesized that, in these pregnant rats, a loss of the balance between prooxidation and antioxidation, particularly in kidneys and heart, disturbs the normal course of pregnancy and leads to manifestations such as gestational hypertension. We thus investigated the presence of oxidative/nitrosative stress in heart and kidneys following high-sodium intake in pregnant rats. Markers of this stress [8-isoprostaglandin F2α (8-iso-PGF2α) and nitrotyrosine], producer of nitric oxide [nitric oxide synthases (NOSs)], and antioxidants [superoxide dismutase (SOD) and catalase] were measured. Then, molecules (Na+-K+-ATPase and aconitase) or process [apoptosis (Bax and Bcl-2), inflammation (monocyte chemoattractant protein-1, connective tissue growth factor, and TNF-α)] susceptible to free radicals was determined. In kidneys from pregnant rats on 1.8% NaCl-water, NOSs, apoptotic index, and nitrotyrosine expression were increased, whereas Na+-K+-ATPase mRNA and activity were decreased. In the left cardiac ventricle of these rats, heightened nitrotyrosine, 8-iso-PGF2α, and catalase activity together with reduced endothelial NOS protein expression and SOD and aconitase activities were observed. These findings suggest that oxidative/nitrosative stress in kidney and left cardiac ventricle destabilizes the normal course of pregnancy and could lead to gestational hypertension.

scholarly journals Relationship Between Body Mass Index and Blood Pressure, Serum Lipids and Lipoproteins in Young Japanese Women.

2002 ◽  
Vol 29 (2) ◽  
pp. 519-521 ◽  
Author(s):  
Tatsuya KAMIHAMA ◽  
Hiroyuki IMAMURA ◽  
Chihiro NISHIMURA ◽  
Kazuhiro UCHIDA ◽  
Noriko MIYAMOTO ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Body Mass ◽  
Serum Lipids ◽  
Japanese Women ◽  
Young Japanese Women ◽  
Lipids And Lipoproteins

Offspring’s blood pressure and metabolic phenotype after exposure to gestational hypertension in utero

2013 ◽  
Vol 28 (1) ◽  
pp. 87-98 ◽  
Author(s):  
Satu Miettola ◽  
Anna-Liisa Hartikainen ◽  
Marja Vääräsmäki ◽  
Aini Bloigu ◽  
Aimo Ruokonen ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Gestational Hypertension ◽  
In Utero ◽  
Metabolic Phenotype
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