scholarly journals Study of human thyroglobulin gene polymorphism

1996 ◽  
Vol 42 (5) ◽  
pp. 34-36
Author(s):  
D. A. Kadyrova ◽  
B. A. Atakhanova ◽  
M. L. Rakhimova ◽  
G. D. Umarova ◽  
Ya. Kh. Turakulov
Keyword(s):  
Genetic Analysis ◽  
Congenital Hypothyroidism ◽  
Population Genetic ◽  
Molecular Genetic ◽  
Restriction Enzymes ◽  
Healthy Individuals ◽  
Population Genetic Analysis ◽  
Genetic Studies ◽  
Blood Samples ◽  
Thyroglobulin Gene

The main goal of this work was to conduct a population genetic analysis of RFLP detected in the TG gene and to develop a system of molecular genetic studies of hereditary thyroid diseases associated with polynucleotide rearrangements in the structure of TG. A population genetic analysis of RFLP detected in the TG gene was carried out. When splitting blood samples of healthy Tashkent residents with EcoRV and Taql restriction enzymes, 2 pairs of alternative variants of normal RFLP were detected - 13.8 or 8.5 and 5.8 or 6.2 bp respectively. In order to detect RFLP in the TG gene for congenital hypothyroidism, DNA samples from 2 families (mother, father, daughter) with a clinical diagnosis of congenital hypothyroidism were analyzed and the same variants of RFLP found in healthy individuals.

scholarly journals Development of microsatellite markers for the house cricket, Acheta domesticus (Orthoptera: Gryllidae)

2020 ◽  
Vol 21 (9) ◽  
Author(s):  
Yash Munnalal Gupta ◽  
SUPATCHAREE TANASARNPAIBOON ◽  
KITTISAK BUDDHACHAT ◽  
SURIN PEYACHOKNAGUL ◽  
PHATTHARAPORN INTHIM ◽  
...  
Keyword(s):  
Genetic Variation ◽  
Genetic Analysis ◽  
Microsatellite Markers ◽  
Population Genetic ◽  
Acheta Domesticus ◽  
House Cricket ◽  
Population Genetic Analysis ◽  
Closely Related Species ◽  
Genetic Studies ◽  
Future Population

Abstract. Gupta YM, Tanasarnpaiboon S, Buddhachat K, Peyachoknagul S, Inthim P, Homchan S. 2020. Development of microsatellite markers for the house cricket, Acheta domesticus (Orthoptera: Gryllidae). Biodiversitas 21: 4094-4099. The house cricket, Acheta domesticus, is one of the species of crickets commonly found in Thailand. Insect breeders in Thailand prefer to breed house cricket as food due to its better taste and popularity among local people. Moreover, largescale breeding industries also breed house cricket to produce cricket-based edible products. Insect breeding industry is growing rapidly and requires primary precaution for sustainable production. To facilitate breeding system to maintain genetic variation in the captive population, we have sequenced the whole genome of A. domesticus to search for simple sequence repeats (SSRs) in order to develop polymorphic microsatellite markers for preliminary population genetic analysis. A total of 112,157 SSRs with primer pairs were identified in our analysis.  Of these, 91 were randomly selected to check for amplification of microsatellite polymorphisms. From these, nine microsatellites were used to check genetic variation in forty-five individuals of A. domesticus from the Phitsanulok population (Thailand).  These microsatellite markers also showed cross-amplification with other three species of edible crickets, specifically Gryllus bimaculatus, Gryllus testaceus, and Brachytrupes portentosus. The microsatellite markers presented herein will facilitate future population genetic analysis of A. domesticus populations. Moreover, the transferability of these makers would also enable researchers to conduct genetic studies for other closely related species.

scholarly journals Quercus Conservation Genetics and Genomics: Past, Present, and Future

Forests ◽  
2021 ◽  
Vol 12 (7) ◽  
pp. 882
Author(s):  
Janet R. Backs ◽  
Mary V. Ashley
Keyword(s):  
Genetic Analysis ◽  
Conservation Genetics ◽  
Population Genetic ◽  
Gap Analysis ◽  
Phylogenetic Study ◽  
Population Genetic Analysis ◽  
Genetic Studies ◽  
Quercus Species ◽  
The Subject ◽  
Genetics And Genomics

Quercus species (oaks) have been an integral part of the landscape in the northern hemisphere for millions of years. Their ability to adapt and spread across different environments and their contributions to many ecosystem services is well documented. Human activity has placed many oak species in peril by eliminating or adversely modifying habitats through exploitative land usage and by practices that have exacerbated climate change. The goal of this review is to compile a list of oak species of conservation concern, evaluate the genetic data that is available for these species, and to highlight the gaps that exist. We compiled a list of 124 Oaks of Concern based on the Red List of Oaks 2020 and the Conservation Gap Analysis for Native U.S. Oaks and their evaluations of each species. Of these, 57% have been the subject of some genetic analysis, but for most threatened species (72%), the only genetic analysis was done as part of a phylogenetic study. While nearly half (49%) of published genetic studies involved population genetic analysis, only 16 species of concern (13%) have been the subject of these studies. This is a critical gap considering that analysis of intraspecific genetic variability and genetic structure are essential for designing conservation management strategies. We review the published population genetic studies to highlight their application to conservation. Finally, we discuss future directions in Quercus conservation genetics and genomics.

scholarly journals Adaptive Evolution of Relish, a Drosophila NF-κB/IκB Protein

Genetics ◽  
2000 ◽  
Vol 154 (3) ◽  
pp. 1231-1238 ◽  
Author(s):  
David J Begun ◽  
Penn Whitley
Keyword(s):  
Immune Response ◽  
Innate Immunity ◽  
Genetic Analysis ◽  
Adaptive Evolution ◽  
Strong Evidence ◽  
Population Genetic ◽  
Microbial Pathogens ◽  
Population Genetic Analysis ◽  
Evolutionary Conflict ◽  
A Site

Abstract NF-κB and IκB proteins have central roles in regulation of inflammation and innate immunity in mammals. Homologues of these proteins also play an important role in regulation of the Drosophila immune response. Here we present a molecular population genetic analysis of Relish, a Drosophila NF-κB/IκB protein, in Drosophila simulans and D. melanogaster. We find strong evidence for adaptive protein evolution in D. simulans, but not in D. melanogaster. The adaptive evolution appears to be restricted to the IκB domain. A possible explanation for these results is that Relish is a site of evolutionary conflict between flies and their microbial pathogens.

Population genetic analysis of Enterocytozoon bieneusi in humans

2012 ◽  
Vol 42 (3) ◽  
pp. 287-293 ◽  
Author(s):  
Wei Li ◽  
Vitaliano Cama ◽  
Yaoyu Feng ◽  
Robert H. Gilman ◽  
Caryn Bern ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Population Genetic ◽  
Enterocytozoon Bieneusi ◽  
Population Genetic Analysis

scholarly journals Population genetic analysis and phylogeny reconstruction in Eucalyptus (Myrtaceae) using high-throughput, genome-wide genotyping

2011 ◽  
Vol 59 (1) ◽  
pp. 206-224 ◽  
Author(s):  
Dorothy A. Steane ◽  
Dean Nicolle ◽  
Carolina P. Sansaloni ◽  
César D. Petroli ◽  
Jason Carling ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
High Throughput ◽  
Population Genetic ◽  
Phylogeny Reconstruction ◽  
Population Genetic Analysis ◽  
Genome Wide

Rhodnius pallescens microsatellite markers for population genetic analysis in Rhodnius ecuadoriensis: preliminary assessment

2019 ◽  
Vol 40 (2) ◽  
Author(s):  
Mario J. Grijalva
Keyword(s):  
Genetic Analysis ◽  
Microsatellite Markers ◽  
Population Genetic ◽  
Preliminary Assessment ◽  
Population Genetic Analysis ◽  
Rhodnius Ecuadoriensis ◽  
Rhodnius Pallescens

Rhodnius ecuadoriensis Lent & León (Hemiptera: Reduviidae) es el prinicipal vector de    la enfermedad de Chagas en Ecuador, donde la estructura genética de sus poblaciones es poco conocida. Nosotros probamos seis Repeticiones Cortas en Tamdem (RCT) de R. pallescens Barber en poblaciones selváticas y domésticas de R. ecuadoriensis. Dos microsatelites fueron monomórficos, dos dieron resultados ambiguos y dos fueron polimórficos (16 y 19 alelos) y fueron utilizados para análisis. Los resultados de las frecuencias alélicas, AMOVA y los pruebas Bayesianas para genética favorecen la teorí­a de la existencia de una sola población. Estos resultados preliminares sugieren que las poblaciones selváticas y domésticas d R. ecuadoriensis intercambian frecuentemente migrantes. Por consiguiente el control de la Enfermedad de Chagas requiere vigilancia entomológica continua en la costa del Ecuador.

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