scholarly journals The influence of xenical on indicators of quality of life in patients with metabolic syndrome

2004 ◽  
Vol 50 (1) ◽  
pp. 22-26
Author(s):  
A. S. Ametov ◽  
T. Yu. Demidova ◽  
A. L. Tselikovskaya

Life quality (LQ) is a multifaceted concept that implies how a human being satisfies his/her physical, mental, and social state. LQ is an indicator that depends on the severity of disease, on therapeutic exposures and reflects his/her subjective assessment of the status during treatment or disease. Life quality was assessed in 60 patients with the metabolic syndrome before and 24 weeks after xenical therapy in combination with a moderate low-calorie diet. The study has revealed that the patients have a low life quality that greatly increases after a complex therapy with xenical and a low-calorie diet.

Diabetes Care ◽  
2005 ◽  
Vol 28 (6) ◽  
pp. 1485-1486 ◽  
Author(s):  
F. Muzio ◽  
L. Mondazzi ◽  
D. Sommariva ◽  
A. Branchi

2004 ◽  
Vol 89 (2) ◽  
pp. 756-760 ◽  
Author(s):  
Marta Garaulet ◽  
Nathalie Viguerie ◽  
Stefan Porubsky ◽  
Eva Klimcakova ◽  
Karine Clement ◽  
...  

Adiponectin, a newly discovered adipose-tissue-specific protein, is thought to be involved in the regulation of insulin action. The aim of the present study was to determine whether adiponectin contributes to the improvement in insulin sensitivity during very-low-calorie diet (VLCD). Biopsies of sc abdominal adipose tissue and blood sampling for analysis of plasma adiponectin and related hormones and metabolites were performed before and at the end of a 4-wk VLCD in 33 nonmorbidly obese women (body mass index, 34.4 ± 4.1 kg/m2). VLCD produced a decrease in weight (7.1 ± 0.4 kg) and in insulin and leptin levels and led to an improvement in insulin sensitivity. Adiponectin gene expression and plasma levels were not modified during calorie restriction. Before VLCD, we found negative correlations between plasma adiponectin and variables related to the metabolic syndrome. Adiponectin mRNA levels showed a negative correlation with lipoprotein a plasma values. The correlations observed before VLCD were not found after VLCD. The data suggest that adiponectin is related to the protection against the metabolic syndrome but is not involved in the regulation of VLCD-induced improvement of insulin sensitivity.


Nutrition ◽  
2019 ◽  
Vol 65 ◽  
pp. 126-130 ◽  
Author(s):  
Leila Sicupira Carneiro de Souza Leão ◽  
Luana Azevedo de Aquino ◽  
Juliana Furtado Dias ◽  
Rosalina Jorge Koifman

2019 ◽  
Vol 28 ◽  
pp. S114-S115
Author(s):  
Tovi Vo ◽  
Lucy Marney ◽  
Julie Mundy ◽  
Gabrielle Edney ◽  
Rayleene Griffin

2022 ◽  
pp. 113706
Author(s):  
Nicole M. Gilbertson ◽  
Natalie Z.M. Eichner ◽  
Julian M. Gaitán ◽  
John M. Pirtle ◽  
Jennifer L. Kirby ◽  
...  

2020 ◽  
Author(s):  
Sara Beigrezaei ◽  
Zeinab Yazdanpanah ◽  
Sepideh Soltani ◽  
Seiedeh Hamideh Rajaei ◽  
Sahar Mohseni-Takalloo ◽  
...  

Abstract Background: Exercise and weight loss diets are two independent non-pharmaceutical strategies known to improve several aspects of body composition and health. We plan to systematically review randomized controlled trials investigating weight loss diets alone compared to weight loss diets in conjunction with exercise on energy intake, body weight, body composition, cardiometabolic risk factors, sex hormones, and mental health. Methods and analysis: PubMed/MEDLINE, EMBASE, ISI (Web of sciences), Scopus, and Google Scholar will be searched to retrieve potential controlled clinical trials investigating the effects of exercise in conjunction with weight-loss diets compared with weight-loss diets alone on energy intake, body weight and composition (fat mass, fat-free mass), anthropometrics (waist circumference), cardiometabolic markers, sex hormones [testosterone, estradiol, and sex hormone binding globulin (SHBG)], liver and kidney enzymes (alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyl transferase (GGT), uric acid, blood urea nitrogen (BUN), and glomerular filtration rate (GFR), quality of life, and depression in adults will be included. The weighted mean difference (WMD) and its corresponding 95% confidence intervals (CIs) will be derived using the random effects model. Several subgroup analyses such as gender, age, BMI, exercise protocol, and diet used for weight loss will be conducted to explore possible sources of heterogeneity. Publication bias will be explored by inspecting funnel plots and by conducting asymmetry tests. Overall quality of the evidence will be assessed by using the NutriGrade scoring system, which is designed to judge the overall quality of meta-analyses of clinical trials conducted in the field of nutrition. Discussion: This proposed systematic review and meta-analysis aims to compare the effects of a low-calorie diet with low-calorie diet plus exercise on the risk factors for chronic diseases. We hope this systematic review and meta-analysis will provide valuable information regarding the values which exercise add to weight-loss diets. No primary data are going to be collected; therefore, ethical approval is not required. The resulting manuscripts will be disseminated in peer-reviewed journals and at international and local conferences. Systematic review registration: This protocol in being considered for registration in the International Prospective Register of Systematic Reviews (PROSPERO).


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