scholarly journals Influence of weight loss on the clinical manifestations of osteoarthritis of the knee-joints.

2017 ◽  
Vol 20 (4) ◽  
pp. 11-18
Author(s):  
Inna Vladimirovna Solov'eva ◽  
Ekaterina Aleksandrovna Strebkova ◽  
Lyudmila Ivanovna Alekseeva ◽  
Ashot Musaelovich Mkrtumyan
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Body Weight ◽  
Clinical Manifestations ◽  
Knee Joints ◽  
Osteoarthritis Of The Knee ◽  
Obese Patients ◽  
Original Publication ◽  
Treatment Of Obesity

Obesity consistently associated with the development of a number of chronic diseases, leading to a decrease in quality of life, disability and death. The article examines the connection between obesity and disease of the musculoskeletal system, describes the mechanisms by means of which obesity leads to the development of osteoarthritis. It is evident that reduction of body mass can slow the progression of osteoporosis. The own experience of non-pharmacological and pharmacological treatment of obesity with the use of orlistat in 50 obese patients with osteoarthritis of the knee IIIII stage is presented. Treatment has resulted in a decrease in body weight, waist circumference, accompanied by a decrease in symptoms osteoarthritis among all the patients. Our results showed that the addition of orlistat to standard osteoarthritis scheme leads to significant reduction in weight and reduction of clinical manifestations of osteoarthritis. According to the above, the drugs that have impact on weight loss, should be included in the treatment regimen of patients with osteoarthritis and obesity. This article is the PeReint of the original publication in Obesity and Metaboilism (2014) 11(4); pp. 41-47. doi: 10.14341/omet2014441-47

scholarly journals Influence of weight loss on the clinical manifestations of osteoarthritis of the knee-joints.

2014 ◽  
Vol 11 (4) ◽  
pp. 41-47 ◽  
Author(s):  
Inna Vladimirovna Solov'eva ◽  
Ekaterina Aleksandrovna Strebkova ◽  
Lyudmila Ivanovna Alekseeva ◽  
Ashot Musaelovich Mkrtumyan
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Body Weight ◽  
Waist Circumference ◽  
Clinical Manifestations ◽  
Knee Joints ◽  
Osteoarthritis Of The Knee ◽  
Obese Patients ◽  
Treatment Of Obesity

Obesity consistently associated with the development of a number of chronic diseases, leading to a decrease in quality of life, disability and death. The article examines the connection between obesity and disease of the musculoskeletal system, describes the mechanisms by means of which obesity leads to the development of osteoarthritis. It is evident that reduction of body mass can slow the progression of osteoporosis. The own experience of non-pharmacological and pharmacological treatment of obesity with the use of orlistat in 50 obese patients with osteoarthritis of the knee II–III stage is presented. Treatment has resulted in a decrease in body weight, waist circumference, accompanied by a decrease in symptoms osteoarthritis among all the patients. Our results showed that the addition of orlistat to standard osteoarthritis scheme leads to significant reduction in weight and reduction of clinical manifestations of osteoarthritis. According to the above, the drugs that have impact on weight loss, should be included in the treatment regimen of patients with osteoarthritis and obesity.

scholarly journals Experience of using sibutramine in combination with microcrystalline cellulose in clinical practice

2020 ◽  
pp. 214-218
Author(s):  
N. A. Petunina ◽  
M. E. Telnova ◽  
E. V. Goncharova ◽  
L. V. Trukhina ◽  
N. S. Martirosyan
Keyword(s):  
Quality Of Life ◽  
Cardiovascular Disease ◽  
Weight Loss ◽  
Body Weight ◽  
Microcrystalline Cellulose ◽  
Positive Impact ◽  
Comprehensive Treatment ◽  
The Metabolic Syndrome ◽  
Treatment Of Obesity

For many years, interest in the issue of obesity has not faded, as obesity is now one of the most common pathologies in the world that directly affects quality of life and lifespan. Even a slight weight loss (5-10% of baseline values) in obese patients is known to improve metabolism and reduce the risk of a range of comorbidities. The article reflects the importance of comprehensive treatment of obesity, presents positive experience of using Reduxin (sibutramine in combination with microcrystalline cellulose) to reduce body weight and risk factors for cardiovascular disease in a specific clinical example in a patient with exogenous-constitutional obesity and eating disorders. The case of obesity in a young man of 24 years old is presented, when other components of the metabolic syndrome (except for arterial hypertension) were not formed. Thus, following the results of 24-week complex treatment, clinically significant reduction of body weight (by 21.7% of initial values) was observed in the patient. The data of psychological researches have shown that the patient has no increase of anxiety and depression level during treatment, but at the same time the indicators of quality of life according to the results of health questionnaire testing have improved. This clinical case corresponds to the results of the PrimaVera program and demonstrates that weight loss during sibutramine therapy in combination with microcrystalline cellulose has a positive impact on the overall health and emotional status of patients and leads to improved quality of life. Therefore, successful treatment of obesity and the maintenance of other outcomes are key to preventing cardiovascular disease.

scholarly journals ОПТИМІЗАЦІЯ КОМПЛЕКСНОГО ЛІКУВАННЯ ІЗ ЗАСТОСУВАННЯМ ПРЕФОРМОВАНИХ ФАКТОРІВ У ЖІНОК У ПОСТМЕНОПАУЗАЛЬНОМУ ПЕРІОДІ, ХВОРИХ НА ОСТЕОАРТРОЗ КОЛІННИХ СУГЛОБІВ

World Science ◽  
2019 ◽  
Vol 2 (11(51)) ◽  
pp. 47-51
Author(s):  
Якименко О. О. ◽  
Кравчук О. Є. ◽  
Коломієць С. М. ◽  
Богдан Н. М.
Keyword(s):  
Quality Of Life ◽  
Drug Therapy ◽  
Effective Treatment ◽  
Clinical Course ◽  
Clinical Manifestations ◽  
Knee Joints ◽  
Osteoarthritis Of The Knee ◽  
Complex Treatment ◽  
Standard Drug

The article presents the issues of complex treatment of osteoarthritis of the knee with the use of preformed factors in postmenopausal women compared to standard drug therapy. The study included 60 women aged 50 to 75 years with clinical manifestations of osteoarthritis of the knee joints in the postmenopausal period. Complex treatment with preformed factors has been found to be an effective treatment for this category of patients, improving the clinical course of osteoarthritis by 53% and improving quality of life.

scholarly journals QUALITY OF LIFE AFTER VERTICAL GASTRECTOMY EVALUATED BY THE BAROS QUESTIONNAIRE

2017 ◽  
Vol 30 (1) ◽  
pp. 14-17 ◽  
Author(s):  
Giselle Abigail MENDES ◽  
Guilherme Pedroso VARGAS
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Sleeve Gastrectomy ◽  
Clinical Improvement ◽  
Average Percentage ◽  
Vertical Gastrectomy ◽  
Satisfactory Outcome ◽  
Treatment Of Obesity ◽  
Late Postoperative Period

ABSTRACT Background: The satisfactory outcome in the surgical treatment of obesity must include, in addition to weight loss, a significant change in the pre-existing comorbidities and in the quality of life. Aim: To evaluate the quality of life in the late postoperative period in patients that underwent videolaparoscopic sleeve gastrectomy. Methods: It was applied the questionnaire "Bariatric Analysis and Reporting Outcome System" (BAROS) in patients that underwent videolaparoscopic sleeve gastrectomy. Results: A total of 47 patients between 21-60 years old were evaluated. The total mean of BMI before surgery was 43.06±5.87 kg/m². The average percentage of the reduction of excess weight after surgery was 85.46±23.6%. The score obtained by patients in the questionnaire about the improvement in the quality of life showed excellent (36.17%), very good (40.43%), good (21.28%) and reasonable (2.13%) results. There was clinical improvement after surgery in all comorbidities investigated. Conclusion: The weight loss was critical to improve the quality of life and offered the resolution or clinical improvement in all of the investigated comorbidities in patients submitted to sleeve gastrectomy.

Experience of weight loss and its burden in patients with non-small cell lung cancer: Results of an online survey.

2016 ◽  
Vol 34 (26_suppl) ◽  
pp. 71-71 ◽  
Author(s):  
Ana Maria Rodriguez ◽  
Elizabeth M Duus ◽  
John Friend
Keyword(s):  
Quality Of Life ◽  
Lung Cancer ◽  
Weight Loss ◽  
Body Weight ◽  
Advanced Nsclc ◽  
Small Cell ◽  
Small Cell Lung ◽  
Appetite Loss ◽  
Nsclc Patients

71 Background: The main objectives of this study were to characterize and compare the burden of non-small cell lung cancer (NSCLC) patients who reported considerable weight loss ( ≥ 5% of their body weight in the past 6 months or ≥ 2% for a BMI less than 20 kg/m2) to those who did not. Methods: 95 advanced NSCLC patients were surveyed from the online patient-powered community PatientsLikeMe. Self-reported demographic and clinical characteristics were recorded. Appetite, distress and concerns, health-related quality of life (QLQ-C15-PAL) and anorexia-cachexia symptoms/concerns (FAACT A/CS) were summarized. The results obtained between patients who lost considerable weight and those who did not were compared, using a two-tailed t-test or a Kruskal-Wallis test. Patients with weight loss were additionally asked open-ended questions on burden and concerns. Results: 35 (37%) patients were classified as having considerable weight loss at the time of the survey and 60 (63%) where classified without. Most patients were female (81%), American (81%), and mean age was 59 years. 61% of patients indicated not receiving either chemotherapy or radiotherapy at the time of the survey. Patients with weight loss reported significantly (p < 0.05) lower overall quality of life (55.2 vs. 66.9), worsened anorexia-cachexia symptoms/concerns (30.7 vs. 36.0), and higher symptomology, specifically fatigue (64.8 vs. 49.1), nausea (19.5 vs. 9.2), and appetite loss (41.0 vs. 23.9) – than patients without weight loss. In addition, significantly more patients who lost weight reported moderate/high distress levels than patients who did not (71% vs. 38%). For patients with weight loss, change in food taste, fatigue, and decrease in appetite were the most frequently reported symptoms with the greatest impact on their lives. Conclusions: Our results support that weight loss negatively affects cancer patients’ quality of life and is associated with more distress and symptoms—particularly fatigue, and appetite loss. Weight loss-related symptoms also significantly impact their lives. Interventions targeted at maintaining/increasing body weight may help to improve well-being and reduce key symptoms in advanced NSCLC patients with considerable weight loss.

scholarly journals Predictive factors for body weight loss and its impact on quality of life following gastrectomy

2017 ◽  
Vol 23 (26) ◽  
pp. 4823 ◽  
Author(s):  
Kazuaki Tanabe ◽  
Masazumi Takahashi ◽  
Takashi Urushihara ◽  
Yoichi Nakamura ◽  
Makoto Yamada ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Weight Loss ◽  
Body Weight ◽  
Predictive Factors ◽  
Body Weight Loss
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