scholarly journals Chronic kidney disease progression in a patient with primary hyperparathyroidism

2016 ◽  
Vol 13 (3) ◽  
pp. 71-75 ◽  
Author(s):  
Svetlana Sergeevna Mirnaya ◽  
Natalia Georgievna Mokrysheva
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Case Report ◽  
Renal Transplantation ◽  
Kidney Disease ◽  
Primary Hyperparathyroidism ◽  
Chronic Kidney Disease Stage ◽  
Disease Stage ◽  
Chronic Kidney Disease Progression ◽  
Kidney Disease Progression

Nowadays cases of severe primary hyperparathyroidism (PHPT) are rare. Doctors of different specialties are informed better about PHPT “masks” and overall PHPT is diagnosed much earlier. We present a case report of a patient with nephrolithiasis and primary hyperparathyroidism with both bone and visceral complications, who showed deterioration of renal function up to chronic kidney disease stage 5 and was referred to renal transplantation.

scholarly journals Cutaneous Manifestations in Patients with Chronic Kidney Disease on Hemodialysis and its Correlation with Renal Function, Dialysis Cycle and Haemoglobin

2018 ◽  
Vol 3 (2) ◽  
pp. 468-474
Author(s):  
Manish Pradhan ◽  
Gaurav Chettri ◽  
Dipa Rai ◽  
Sagar Paudel
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Serum Creatinine ◽  
Skin Disease ◽  
Skin Diseases ◽  
Chronic Kidney Disease Stage ◽  
Disease Stage ◽  
Cutaneous Manifestations ◽  
Skin Manifestation

Introduction: Skin is the mirror of an internal disease, including the renal system. Chronic kidney disease presents with variety of skin diseases, which is caused either by kidney disease or by treatment modalities.Objective: To evaluate the revalence of various skin disease in patients with chronic renal disease and relation of various skin diseases with serum creatinine, blood urea, hemoglobin and number of hemodialysis cycle.Methodology: A cross-sectional analytical study was conducted in hundred patients of either sex, aged 18 years and above; with chronic kidney disease (stage V) admitted for dialysis in Nephrology department of Nobel Medical College and teaching hospital, Biratnagar, Nepal. The study groups were evaluated for various skin manifestation and parameters of renal function like blood urea and serum creatinine.Results: Among the total patients (n=100), 84 patients presented with complain of skin manifestation but on detail examination 97 patients had at least one skin disease. The causes leading to chronic kidney disease were found to be hypertension 58%, diabetes mellitus 49%, IgA nephropathy 7%, systemic lupus erythematosus 7% and glomerulonephritis 4%. Xerosis was the commonest skin disease encountered in these patients amounting to 71% among which 43 were hypertensive and 34 were diabetic. Xerosis was followed by pruritus (62%), pallor (54%), mucosal changes (39%), skin infection (36%), hair changes (34%), pigmentation (33%) and nail changes (29%). Serum creatinine showed statistically significant association with pruritus ( =0.030) and  pigmentation ( =0.010), similarly blood urea showed significant association with pruritus ( =0.001). Similarly, number of dialysis cycle showed significant association with pigmentation of skin ( =<0.001).Conclusion: Chronic kidney disease is associated with variety of skin diseases. The commonest were xerosis and pruritus. Early detection and appropriate intervention can relieve and decrease suffering.  BJHS 2018;3(2)6:468-474.

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