scholarly journals Evaluation of effectiveness of contact transscleral diode laser cyclocoagulation drainage after neovascular glaucoma surgery

2017 ◽  
Vol 20 (4) ◽  
pp. 257-262
Author(s):  
Dmitry V. Lipatov ◽  
Timofey A. Chistykov ◽  
Anatoly G. Kuzmin ◽  
Anna A. Tolkacheva
Keyword(s):  
Intraocular Pressure ◽  
Diode Laser ◽  
Postoperative Period ◽  
Glaucoma Surgery ◽  
Neovascular Glaucoma ◽  
Elevated Intraocular Pressure ◽  
Patients With Diabetes ◽  
History Of ◽  
Ophthalmic Branch ◽  
Attending Physicians

Relevance. Recently, drainage surgery has gained prevalence in the treatment of neovascular glaucoma. Unfortunately, studies have reported that their effectiveness does not exceed 70%80%. During the postoperative period, the attending physicians major concern is the normalisation of high IOP. Aim.To evaluate the effectiveness of contact transscleral diode laser cyclocoagulation drainage after neovascular glaucoma surgery, which did not lead to the normalisation of elevated intraocular pressure. Materials and methods. This study enrolled eight patients in the ophthalmic branch of the Endocrinology Research Center. All patients previously underwent a drainage operation for uncompensated secondary neovascular glaucoma with a history of diabetic retinopathy. During the postoperative period, because intraocular pressure failed to stabilise, we performed contact transscleral diode laser cyclocoagulation as per the original methodology. Results. After the execution of contact transscleral diode laser cyclocoagulation, intraocular pressure was compensated in all patients, and any complication was noted for up to 6 months. Conclusion. Contact transscleral diode laser cyclocoagulation can be used to normalise abnormal IOP after drainage surgery for the treatment of neovascular glaucoma in patients with diabetes mellitus.

scholarly journals Incidence of elevated intraocular pressure after intravitreal injection in Japanese patients with age-related macular degeneration

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maiko Maruyama-Inoue ◽  
Tatsuya Inoue ◽  
Shaheeda Mohamed ◽  
Yoko Kitajima ◽  
Shoko Ikeda ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intraocular Pressure ◽  
Macular Degeneration ◽  
Intravitreal Injection ◽  
Odds Ratio ◽  
Japanese Patients ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Elevated Intraocular Pressure ◽  
History Of

AbstractThe purpose of this study was to report the incidence of elevated intraocular pressure (IOP) after intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF) in Japanese patients with age-related macular degeneration (AMD). A retrospective study of chart review of patients who underwent ≥ 10 intravitreal anti-VEGF injections between April 2009 and December 2019 was conducted. Elevated IOP was defined as IOP ≥ 25 mmHg at one visit. Cases with elevated IOP resulting from IVI were identified. Furthermore, the association between elevated IOP and some parameters, as the risk factors that influence elevated IOP, was investigated. A total of 402 eyes of 370 patients were included in this study. Twenty-eight eyes of 26 patients (7.0%) were identified as cases with elevated IOP after IVI. The mean time of elevation after baseline was 50.6 ± 26.5 months. History of glaucoma (p = 0.021; odds ratio, 5.85), treatment modality (p = 0.019; odds ratio, 6.32), and total number of injections (p = 0.003; odds ratio, 1.03) were significantly associated with elevated IOP. A late complication of elevated IOP is associated with IVI in patients with AMD. Particularly, history of glaucoma and treat and extend regimen with frequent injections were found to be risk factors of elevated IOP.

scholarly journals Comparison between the Express Implant and Transscleral Diode Laser in Neovascular Glaucoma

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Faried Mohammed Wagdy ◽  
Adel Galal Zaky
Keyword(s):  
Previous History ◽  
Visual Outcome ◽  
Glaucoma Surgery ◽  
Neovascular Glaucoma ◽  
Panretinal Photocoagulation ◽  
History Of ◽  
Therapeutic Tools ◽  
Endothelial Growth Factor ◽  
Glaucoma Filtration Device ◽  
Filtration Device

Purpose. To compare the outcomes of Ex-PRESS glaucoma filtration device and transscleral cyclophotocoagulation (TSCP) in the management of neovascular glaucoma (NVG). Patients and Methods. A total of 30 eyes (12 express shunts and 18 TSCP) of 28 patients were included. The eyes had NVG with intraocular pressure (IOP) more than 21 mmHg of the maximally tolerated medication treatment after previous panretinal photocoagulation and antivascular endothelial growth factor (anti-VEGF) injection, with no previous history of a cyclodestruction procedure or glaucoma surgery, were randomized either for Ex-PRESS glaucoma filtration device or TSCP. The patients were followed up weekly for the first month and then monthly for 12 months as regard to the IOP, number of topical antiglaucoma drugs required, visual outcome, and postoperative complications. Results. IOP was successfully controlled with both techniques in 83.3% of the eyes. Both techniques had fewer complications and required fewer subsequent procedures. Conclusion. Both the Ex-PRESS glaucoma filtration device and TSCP might constitute safe and alternative therapeutic tools for patients with NVG. However, TSCP is an easier procedure, less time consuming, and does not require a learning curve.

scholarly journals Iris-Occlusion of XEN Gel Stent following Ab Externo Transconjunctival Implantation Technique

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Sunil Ruparelia ◽  
Nir Shoham-Hazon
Keyword(s):  
Intraocular Pressure ◽  
Postoperative Complications ◽  
Minimally Invasive ◽  
Stent Implantation ◽  
Rare Case ◽  
Surgical Techniques ◽  
Glaucoma Surgery ◽  
Implantation Technique ◽  
Xen Gel Stent ◽  
Elevated Intraocular Pressure

The use of minimally invasive glaucoma surgery (MIGS) devices has become increasingly common for the management of elevated intraocular pressure (IOP) in the context of glaucoma. These technologies have traditionally been associated with fewer postoperative complications than conventional surgical techniques. However, we report on a rare case of transient XEN occlusion associated with pupil dilation following XEN gel stent implantation. This case highlights that in future XEN implantations, it may be preferable to position the XEN at a lesser angle to the iris to prevent such an occlusion. The use of different positionings of XEN is performed to optimize outcomes. However, it is highlighted that complications may arise in certain circumstances.

scholarly journals Glaucoma and its predictors among adult patients attending ophthalmic outpatient department: a hospital-based study, North West Ethiopia

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Gashaw Mehiret Wubet ◽  
Abiyu Ayalew Assefa
Keyword(s):  
Intraocular Pressure ◽  
Family History ◽  
Public Awareness ◽  
Statistical Significance ◽  
Positive Family History ◽  
Contributing Factors ◽  
North West ◽  
Elevated Intraocular Pressure ◽  
North West Ethiopia ◽  
History Of

Abstract Background Nearly 1.9% of global blindness is caused by glaucoma and this is sadly high in Africa which is around 15% and In Ethiopia, glaucoma is responsible for 5.2% of blindness. It is also the fifth cause of blindness in Ethiopia. Scarce information is available regarding glaucoma in Ethiopia; hence we determined the proportion of glaucoma and its associated factors in North West Ethiopia which will be utilized for future related researches and different stakeholders. Methods Institution based cross-sectional study was conducted from September 1/2020 to February 30/21 among 258 adults aged 40 and above years old. The participants were selected using the systematic random sampling technique. The data was collected using an interview-administered questionnaire. Binary and Multi-variable logistic regressions were fitted to identify independent predictors of glaucoma. P-value less than 0.05 were used as a cutoff point for declaring statistical significance. Results The prevalence of glaucoma was 66(26%) with a 95% CI of 17.7, 35.4%). Individuals with Positive family history of glaucoma (AOR: 3.72, 95% CI: 1.03–3.53), age (AOR: 3.21, 95% CI: 1.92–5.99) and elevated intraocular pressure (AOR: 3.09, 95% CI: 1.45–6.59) were statistically significant contributing factors for the development of glaucoma. Conclusion The study found a relatively high proportion of glaucoma in the study area, which is primarily a disease of the elderly. Age, elevated intraocular pressure, and positive family history of glaucoma was contributing factors for the emergence of glaucoma. Therefore, establishing public awareness programs about the identified risk factors for the prevention and early detection of cases is essential.

Micropulse transscleral cyclophotocoagulation using a standard protocol in patients with refractory glaucoma naive of cyclodestruction

2019 ◽  
pp. 112067211987758 ◽  
Author(s):  
Soufiane Souissi ◽  
Christophe Baudouin ◽  
Antoine Labbé ◽  
Pascale Hamard
Keyword(s):  
Intraocular Pressure ◽  
Diode Laser ◽  
Glaucoma Surgery ◽  
Refractory Glaucoma ◽  
Corrected Visual Acuity ◽  
Pressure Lowering ◽  
Transscleral Cyclophotocoagulation ◽  
The Mean ◽  
Diode Laser Cyclophotocoagulation

Purpose: To assess the efficacy and safety of a standardized micropulse transscleral diode laser cyclophotocoagulation procedure in refractory glaucoma. Methods: Retrospective, interventional study in a series of 37 consecutive patients with refractory glaucoma, cyclodestructive procedure-naive, who underwent micropulse transscleral diode laser cyclophotocoagulation from December 2016 to October 2017. A successful laser treatment was defined as (1) intraocular pressure between 6 and 18 mm Hg; (2) 20% of baseline intraocular pressure reduction; (3) no additional glaucoma medications; (4) no decrease in vision due to complications or change in intraocular pressure; and (5) no need for additional glaucoma surgery except micropulse transscleral diode laser cyclophotocoagulation retreatment. Results: Mean age was 60.2 years. Mean follow-up was 9.7 ± 3.9 months. The mean preoperative intraocular pressure (28.7 mm Hg) significantly decreased to 21.0 mm Hg at 1 month, 18.5 mm Hg at 3 months, 18.4 mm Hg at 6 months, and 18.5 mm Hg at 12 months ( p < 0.01 at all time points). The mean number of preoperative glaucoma medications (4.7) decreased to 4.0 at 1 month ( p = 0.14), 4.5 at 3 months ( p < 0.05), 3.9 at 6 months ( p < 0.05), and 3.6 at 12 months ( p < 0.05). At 1 year, the success rate was 35% with a mean intraocular pressure lowering of 36%. One patient had hypotony and a loss of best-corrected visual acuity. Mild transient postoperative inflammation was observed in 8% of the cases. Conclusion: Using a standardized procedure, micropulse transscleral diode laser cyclophotocoagulation allows a mild intraocular pressure decrease with a low rate of complications and thus achieves a relatively good profit risk benefit, mostly for moderately hypertensive refractory glaucoma.

scholarly journals Combining Ab Interno Kahook Trabeculectomy with Gonioscopy-Assisted Transluminal Trabeculotomy Reduces Intraocular Pressure

2019 ◽  
Vol 184 (11-12) ◽  
pp. 934-936
Author(s):  
Jared R Widder ◽  
Joseph W Schmitz
Keyword(s):  
Intraocular Pressure ◽  
Surgical Technique ◽  
Open Angle Glaucoma ◽  
Glaucoma Surgery ◽  
Active Duty ◽  
Pharmacologic Therapy ◽  
Open Angle ◽  
Elevated Intraocular Pressure ◽  
Kahook Dual Blade ◽  
Ab Interno

Abstract Minimally invasive glaucoma surgery (MIGS) provides a safe option for individuals with mild to moderate open-angle glaucoma to reduce their need for pharmacologic therapy or more extensive ab externo surgeries. In this report, we describe a surgical technique using both the Kahook Dual Blade and Gonioscopy-assisted transluminal trabeculotomy (GATT), to treat a 23-year-old active duty female with idiopathic uveitis and subsequent corticosteroid-induced glaucoma who presented with consistently elevated intraocular pressure (IOP) measurements despite maximal pharmacologic interventions. This combination was effective in consistently lowering intraocular pressure for at least 12 months in a young, phakic, active duty patient with uveitis and steroid-responsive open-angle glaucoma.

scholarly journals Acute Glaucoma Filtering Surgery Failure following Herpes Zoster Ophthalmicus Infection

2021 ◽  
pp. 324-329
Author(s):  
Stylianos A. Kandarakis ◽  
Andreas Diagourtas ◽  
Petros Petrou ◽  
Filippos Vingopoulos ◽  
Konstantinos Droutsas ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Herpes Zoster ◽  
Open Angle Glaucoma ◽  
Filtering Surgery ◽  
Herpes Zoster Ophthalmicus ◽  
History Of ◽  
The Right ◽  
Ophthalmic Branch ◽  
Acute Failure ◽  
Common Infection

Herein, we report a case of acute failure of a previously successful trabeculectomy, following an infection with herpes zoster ophthalmicus (HZO). HZO remains a common infection, especially among elderly and immunocompromised patients. There is a strong link between HZO infection, the incidence of secondary glaucoma, and the need for glaucoma filtering surgery. Though, to our knowledge, there are no cases reporting on the effect that a concomitant infection may have on a previously successful trabeculectomy. In our case, a 76-year-old immunocompetent male with primary open-angle glaucoma in both eyes and a history of a successful right eye trabeculectomy 1 year earlier presented with acute primary HZO involving the ophthalmic branch of the right trigeminal nerve. Appropriate topical and systemic treatment was immediately initiated. Three days later, the trabeculectomy bleb showed hyperemia and flattening and concomitant rise of intraocular pressure was noted. A week later, the cutaneous signs were improving yet the trabeculectomy had failed and high intraocular pressure was established, requiring both topical and systemic antiglaucoma medications. Our study suggests that a previously successful trabeculectomy may manifest signs of compromise and subsequent failure following a HZO infection.

Intracameral Avastin Dramatically Resolves Iris Neovascularization and Reverses Neovascular Glaucoma

2008 ◽  
Vol 18 (2) ◽  
pp. 255-262 ◽  
Author(s):  
K.V. Chalam ◽  
S.K. Gupta ◽  
S. Grover ◽  
V.S. Brar ◽  
S. Agarwal
Keyword(s):  
Visual Acuity ◽  
Intraocular Pressure ◽  
Outcome Measure ◽  
Glaucoma Surgery ◽  
Pressure Control ◽  
Neovascular Glaucoma ◽  
Slit Lamp ◽  
Snellen Visual Acuity ◽  
Iris Neovascularization ◽  
Biologic Effect

Purpose To report the biologic effect of intracameral bevacizumab in patients with iris neovascularization secondary to proliferative retinal vasculopathies. Methods Sixteen eyes of 15 patients with iris neovascularization associated with or without neovascular glaucoma secondary to proliferative retinal vasculopathies received intracameral bevacizumab (1.25 mg). Ophthalmic evaluations included Snellen visual acuity (VA), complete ophthalmic examination, fluorescein iris angiography, and slit lamp photography Main outcome measure was change in degree of iris neovascularization. Secondary outcomes included fluorescein iris angiographic leakage, control of intraocular pressure, and changes in VA. Results All patients with neovascularization demonstrated by slit lamp photography and fluorescein angiography (16/16 eyes) had complete (or at least partial) reduction in leakage of the neovascularization within 3 weeks after the injection. Leakage from iris neovascularization resolved in 12 of 16 (75%) eyes. In two cases recurrent leakage was seen as early as 4 weeks necessitating repeat injection. Intraocular pressure was controlled with maximum medical therapy in eight of nine eyes reducing the need for glaucoma surgery. Visual acuity improved from a median of hand motions to 20/200. Conclusions In summary, intracameral bevacizumab was effective in reversing iris neovascularization in the majority of patients. It also facilitated intraocular pressure control in patients with associated glaucoma.

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