scholarly journals THE TIME DELAY OF AIR/OXYGEN MIXTURE DELIVERY AFTER THE CHANGE OF SET FIO2: AN IMPROVEMENT OF A NEONATAL MATHEMATICAL MODEL

2020 ◽  
Vol 49 (3) ◽  
pp. 77-82
Author(s):  
Leoš Tejkl ◽  
Jakub Ráfl ◽  
Petr Kudrna

<p>Oxygen therapy is an essential treatment of premature infants suffering from hypoxemia. Normoxemia is maintained by an adjustment of the fraction of oxygen (FiO<sub>2</sub>) in the inhaled gas mixture that is set manually or automatically based on peripheral oxygen saturation (SpO<sub>2</sub>). Automatic closed-loop systems could be more successful in controlling SpO<sub>2</sub> than traditional manual approaches. Computer models of neonatal oxygen transport have been developed as a tool for design, validation, and comparison of the automatic control algorithms. The aim of this study was to investigate and implement the time delay of oxygen delivery after a change of set FiO<sub>2</sub> during noninvasive ventilation support to enhance an available mathematical model of neonatal oxygen transport. The time delay of oxygen delivery after the change of FiO<sub>2</sub> during the noninvasive nasal Continuous Positive Airway Pressure (nCPAP) ventilation support and during the High Flow High Humidity Nasal Cannula (HFHHNC) ventilation support was experimentally measured using an electromechanical gas blender and a physical model of neonatal lungs. Results show the overall time delay of the change in the oxygen fraction can be divided into the baseline of delay, with a typical time delay 5.5 s for nCPAP and 6.5 s for HFHHNC s, and an exponential rising phase with a time constant about 2–3 s. A delay subsystem was implemented into the mathematical model for a more realistic performance when simulating closed-loop control of oxygenation.</p>

2014 ◽  
Vol 2014 ◽  
pp. 1-11
Author(s):  
Yong-Ren Pu ◽  
Thomas A. Posbergh

The problem of stabilization of rigid bodies has received a great deal of attention for many years. People have developed a variety of feedback control laws to meet their design requirements and have formulated various but mostly open loop numerical algorithms for the dynamics of the corresponding closed loop systems. Since the conserved quantities such as energy, momentum, and symmetry play an important role in the dynamics, we investigate the conserved quantities for the closed loop control systems which formally or asymptotically stabilize rigid body rotation and modify the open loop numerical algorithms so that they preserve these important properties. Using several examples, the authors first use the open loop algorithm to simulate the tumbling rigid body actions and then use the resulting closed loop one to stabilize them.


1999 ◽  
Vol 122 (3) ◽  
pp. 454-460 ◽  
Author(s):  
Vikram Kapila ◽  
Anthony Tzes ◽  
Qiguo Yan

Input shaping techniques reduce the residual vibration in flexible structures by convolving the command input with a sequence of impulses. The exact cancellation of the residual structural vibration via input shaping is dependent on the amplitudes and instances of impulse application. A majority of the current input shaping schemes are inherently open-loop where impulse application at inaccurate instances can lead to system performance degradation. In this paper, we develop a closed-loop control design framework for input shaped systems. This framework is based on the realization that the dynamics of input shaped systems give rise to time delays in the input. Thus, we exploit the feedback control theory of time delay systems for the closed-loop control of input shaped flexible structures. A Riccati equation-based and a linear matrix inequality-based frameworks are developed for the stabilization of systems with uncertain, multiple input delays. Next, the aforementioned framework is applied to two input shaped flexible structure systems. This framework guarantees closed-loop system stability and performance when the impulse train is applied at inaccurate instances. Two illustrative numerical examples demonstrate the efficacy of the proposed closed-loop input shaping controller. [S0022-0434(00)00103-9]


10.29007/btv1 ◽  
2019 ◽  
Author(s):  
Diego Manzanas Lopez ◽  
Patrick Musau ◽  
Hoang-Dung Tran ◽  
Taylor T. Johnson

This benchmark suite presents a detailed description of a series of closed-loop control systems with artificial neural network controllers. In many applications, feed-forward neural networks are heavily involved in the implementation of controllers by learning and representing control laws through several methods such as model predictive control (MPC) and reinforcement learning (RL). The type of networks that we consider in this manuscript are feed-forward neural networks consisting of multiple hidden layers with ReLU activation functions and a linear activation function in the output layer. While neural network con- trollers have been able to achieve desirable performance in many contexts, they also present a unique challenge in that it is difficult to provide any guarantees about the correctness of their behavior or reason about the stability a system that employs their use. Thus, from a controls perspective, it is necessary to verify them in conjunction with their corresponding plants in closed-loop. While there have been a handful of works proposed towards the verification of closed-loop systems with feed-forward neural network controllers, this area still lacks attention and a unified set of benchmark examples on which verification techniques can be evaluated and compared. Thus, to this end, we present a range of closed-loop control systems ranging from two to six state variables, and a range of controllers with sizes in the range of eleven neurons to a few hundred neurons in more complex systems.


2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Yan Qi ◽  
Min Zhang ◽  
Zhiguo Yan

This paper deals with the problem of mixed H2/H∞ control for Itô-type stochastic time-delay systems. First, the H2/H∞ control problem for stochastic time-delay systems is presented, which considers the mean square stability, H2 control performance index, and the ability of disturbance attenuation of the closed-loop systems. Second, by choosing an appropriate Lyapunov–Krasoviskii functional and using matrix inequality technique, some sufficient conditions for the existence of state feedback H2/H∞ controller for stochastic time-delay systems are obtained in the form of linear matrix inequalities. Third, two convex optimization problems with linear matrix inequality constraints are formulated to design the optimal mixed H2/H∞ controller which minimizes the guaranteed cost of the closed-loop systems with known and unknown initial functions, and the corresponding algorithm is given to optimize H2/H∞ performance index. Finally, a numerical example is employed to show the effectiveness and feasibility of the proposed method.


Author(s):  
L. Johan Persson ◽  
Andrew R. Plummer ◽  
Christopher R. Bowen ◽  
Ian Brooks

This paper describes the design, simulation and testing of a piezoelectric spool valve. An actuator has been connected to the valve and tested under closed loop control. A mathematical model of the valve was produced and a prototype of the valve was tested. The mathematical model is validated against the experimental data. Step and frequency responses for both the valve and actuator are presented. It was found that displacement of the hydraulic fluid by the ring bender had an impact on the valve performance. To reduce the effect of the piezoelectric hysteresis, closed loop spool position control was evaluated. A noticeable difference can be observed between open loop and closed loop performance.


2021 ◽  
Vol 26 (2) ◽  
pp. 162-171
Author(s):  
E.L. Litinskaia ◽  

Insulin therapy automation is an actual research line in the glycemic control of diabetes mellitus type 1 patients. Development of closed-loop systems and methods will allow blood glucose maintaining in the physiological range. The work proposes the personalized insulin therapy system considered as a closed-loop control system based on feedback and external disturbances compensation principles. Automatic feedback-based glycemic control includes proportional reg-ulation of basal insulin infusion rate in relation to optimized thresholds inside the target range. To achieve bidirectional glycemic regulation the author proposes model predictive control for calculation of not only optimal profile of bolus infusion but also recommended corrective dose of carbohydrates. Besides, the comparative analysis of trends in measured and predicted profiles of blood glucose allows detecting and compensation of its unpredicted deviations. In silico testing of developed algorithms on nine virtual adults for 72 hours shows an ability for glucose maintaining in the target range for whole system operation time.


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