scholarly journals Obesity, but not polycystic ovary syndrome, affects circulating markers of low-grade inflammation in young women without major cardiovascular risk factors

HORMONES ◽  
2015 ◽  
pp. 251-257 ◽  
Author(s):  
Cristiano Roberto Barcellos ◽  
Michelle Patrocínio Rocha ◽  
Sylvia Asaka Hayashida ◽  
Wagner Silva Dantas ◽  
Viviane dos Reis Vieira Yance ◽  
...  
Open Medicine ◽  
2008 ◽  
Vol 3 (3) ◽  
pp. 257-270 ◽  
Author(s):  
Ioana Ilie ◽  
Carmen Pepene ◽  
Ileana Duncea ◽  
Razvan Ilie

AbstractPolycystic ovary syndrome (PCOS) is possibly the most common endocrinopathy of reproductive age, characterized by hyperandrogenism and oligomenorrhea. Additionally, approximately one-third to one-half of all women and adolescent girls with PCOS tend to fulfill many of the metabolic syndrome criteria, and many view PCOS as a premetabolic syndrome condition, predisposing to a high risk for cardiovascular disease. Endothelial dysfunction, impaired arterial structure, or proinflammatory markers are early features of atherosclerosis, and can be used as surrogate indicators of future coronary artery disease in women with PCOS. However, as the latest studies show, these symptoms are the result of deleterious effects that cardiovascular risk factors, in particular insulin resistance and obesity, produce on the vascular wall, rather than to the presence of PCOS per se. The relationship between hyperandrogenemia and the risk of cardiovascular disease is controversial and needs to be clarified. Further research is warranted to understand the pathogenesis of cardiovascular disease in PCOS, and to identify subtypes of PCOS in which the presence of cardiovascular risk factors may result in increased cardiovascular events, leading to high morbidity or mortality rates caused by cardiovascular disease.


2005 ◽  
Vol 113 (S 1) ◽  
Author(s):  
S Tan ◽  
S Hahn ◽  
K Pleger ◽  
S Sack ◽  
BL Herrmann ◽  
...  

2009 ◽  
pp. 1-7
Author(s):  
Tanzeela Akram ◽  
Shahid Hasan ◽  
Muhammad Imran ◽  
Asima Karim ◽  
Muhammad Arslan

2007 ◽  
Vol 88 (2) ◽  
pp. 519-522 ◽  
Author(s):  
Ivan Araujo Penna ◽  
Paulo Roberto Bastos Canella ◽  
Carolina Sales Vieira ◽  
Marcos Felipe Silva de Sá ◽  
Rosana Maria dos Reis ◽  
...  

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