scholarly journals Sertoli cell tumor and gonadoblastoma in an untreated 29-year-old 46,XY phenotypic male with Frasier syndrome carrying a WT1 IVS9+4C>T mutation

HORMONES ◽  
2012 ◽  
Vol 11 (3) ◽  
pp. 361-367 ◽  
Author(s):  
Sophia Kitsiou-Tzeli ◽  
Maria Deligiorgi ◽  
Sophia Malaktari-Skarantavou ◽  
Charalampos Vlachopoulos ◽  
Spyridon Megremis ◽  
...  
Keyword(s):  
Sertoli Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor ◽  
Frasier Syndrome ◽  
Phenotypic Male

Inoperable Ovarian Sertoli Cell Tumor in an Elderly Patient, Case Report and Review of Literature

2017 ◽  
Vol 10 (1) ◽  
Author(s):  
Bedoudou H ◽  
Aboueljaoud B ◽  
Mai A ◽  
Banani A ◽  
Alaoui Lamrani Y ◽  
...  
Keyword(s):  
Elderly Patient ◽  
Case Report ◽  
Sertoli Cell ◽  
Cell Tumor ◽  
Review Of Literature ◽  
Sertoli Cell Tumor ◽  
Patient Case

Testicular Tumors—Some New and a Few Perennial Problems

2008 ◽  
Vol 132 (4) ◽  
pp. 548-564 ◽  
Author(s):  
Robert H. Young
Keyword(s):  
Germ Cell ◽  
Sertoli Cell ◽  
Leydig Cell ◽  
Yolk Sac ◽  
Cell Tumor ◽  
Yolk Sac Tumor ◽  
Female Gonad ◽  
Sertoli Cell Tumor ◽  
Older Patient ◽  
Testicular Tumors

Abstract The histopathology of testicular tumors is presented, emphasizing new, unusual, or underemphasized aspects. Within the category of seminoma of the usual type, the recent literature has drawn attention to the presence in occasional tumors of solid or hollow tubules or spaces of varying sizes and shape that may result in cribriform or microcystic patterns, causing potential confusion with other neoplasms, most notably Sertoli cell tumor or yolk sac tumor. Although regions of typical neoplasia and awareness of this phenomenon usually will be diagnostic, immunohistochemistry may play a role in excluding Sertoli cell tumor or yolk sac tumor. Although immunohistochemistry can play an undoubted helpful role in this and selected other areas of testicular tumor evaluation, careful evaluation of the gross and routine microscopic features will solve the vast majority of diagnostic problems. An excellent review of immunohistochemistry in this area by R. E. Emerson, MD, and T. M. Ulbright, MD, is cited herein. Spermatocytic seminoma remains a crucial pitfall in diagnosis, and the pathologist must always be alert to the possible diagnosis when looking at a seminomatous neoplasm, particularly in an older patient, although about one third of these tumors occur in the usual seminoma age range. The embryonal carcinoma has a great diversity of patterns, which are briefly noted. The enigmatic and picturesque tumor, polyembryoma, which virtually never occurs in pure form but may be a confusing component of a variety of mixed germ cell tumors, is discussed and illustrated. The phenomenon of burnt-out germ cell neoplasia is also briefly noted and an excellent recent contribution is referred to. Within the sex cord–stromal family of neoplasms, recent contributions and elaborations of unusual morphologic features of Leydig cell tumors and Sertoli cell tumors are presented. Within the Leydig cell family, cyst formation, adipose metaplasia, calcification or ossification, and spindle cell patterns may be particularly confusing, and in the Sertoli cell family, a great array of patterns caused by differing admixtures of tubular, solid, and stromal components occur. The peculiar lesion, intratubular large cell hyalinizing Sertoli cell tumor, of young boys with Peutz-Jeghers syndrome, is briefly discussed. Some of the problems in the family of hematopoietic neoplasms are reviewed, these processes posing diverse problems in differential diagnosis and their correct recognition having crucial therapeutic implications. Although secondary tumors to the testis have not received the same attention in the literature as the similar phenomenon in the female gonad, remarkable examples of testicular spread of diverse neoplasms, usually carcinoma but rarely melanoma, are seen, and the pathologist should be alert to this possibility, particularly when examining an unusual morphology in an older patient. Finally, a few comments are made on the common paratesticular neoplasm, the adenomatoid tumor, highlighting its varied patterns and recent description of some of the issues that may arise when they undergo total or subtotal infarction.

Sertoli Cell Tumor

2022 ◽  
pp. 1349-1354
Author(s):  
Cynthia M. Faux ◽  
Marcie L. Logsdon
Keyword(s):  
Sertoli Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor

NSE positive Sertoli cell tumor of the testis: case report and literature review

2020 ◽  
Vol 216 (8) ◽  
pp. 152990
Author(s):  
Gregor Mikuz ◽  
Elisabeth Wadl ◽  
Pavlos Raptis ◽  
Klaus Jeschke ◽  
Hermann Rogatsch
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Sertoli Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor

Large-Cell Calcifying Sertoli Cell Tumor

1989 ◽  
Vol 141 (4) ◽  
pp. 953-954 ◽  
Author(s):  
Joseph J. Buchino ◽  
John J. Buchino ◽  
Eric R. Uhlenhuth
Keyword(s):  
Sertoli Cell ◽  
Large Cell ◽  
Cell Tumor ◽  
Sertoli Cell Tumor
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