scholarly journals The Role of Periodontal Disease in Preterm Labour - A Prospective Cohort Study (A Path Analysis) from Iran

2021 ◽  
Vol 10 (17) ◽  
pp. 1228-1234
Author(s):  
Mohammad Mahdi Farshad

BACKGROUND Periodontal infections are the most common oral diseases in pregnancy. This condition can cause complications during pregnancy. Therefore, this study was designed to determine the factors affecting preterm birth and their relationship with periodontal diseases. METHODS This was a prospective cohort study and the population, consisted of old women in the age group of 18 – 45 years attending prenatal care centers in their second trimester of pregnancy. After obtaining informed and free consent from the female parent, a periodontal examination was performed and her medical information was recorded. Examination of Rumford’s teeth was performed to assess the severity of gingivitis, plaque, calculus, and attachment loss. AMOS software was used to investigate the association between preterm labor and delivery and to provide a conceptual model. RESULTS The consequences showed a direct association between preterm labour and factors, such as attachment loss, calculus, bleeding on probing (BOP), age, current diabetes, gestational diabetes, gestational hypertension, lack of calcium, folic acid, and iron supplementation, mothers’ depression, polyhydramnios, smoking severity, and history of premature rupture of the membrane. The results also indicated an indirect relationship between irregular tooth brushing and preterm birth. CONCLUSIONS Attachment loss, calculus, bleeding on probing, are directly related to premature labour and irregular tooth brushing is indirectly associated with early birth. Due to the direct relationship between periodontal diseases and preterm delivery, regular brushing, oral hygiene, oral examinations during pregnancy and follow-up treatment of periodontal disease during pregnancy are recommended. KEY WORDS Periodontal Disease, Preterm Labour, Cohort Study, Path Analysis, Pregnancy

2020 ◽  
Author(s):  
Mohammad MAHDI Farshad ◽  
Afshin Khorsand ◽  
Masoomeh kheirkhah ◽  
Ahmad Reza Shamshiri

Abstract Background: Periodontal infections are the most common oral diseases in pregnancy. This condition can cause complications during pregnancy. Therefore, this study was designed to determine the factors affecting preterm birth and their relationship with periodontal diseases. Methods: This was a prospective cohort study and the population, consisted of women 18-45 years attending prenatal care centers in their second trimester of pregnancy. After obtaining informed and free consent from the female parent, a periodontal examination was performed and her medical information was recorded. Examination of Rumford’s teeth was performed to assess the severity of gingivitis, plaque, calculus, and attachment loss, and AMOS software was used to investigate the association between preterm labor and delivery and to provide a conceptual model. Results: The consequences showed a direct association between preterm labor and factors, such as attachment loss, calculus , bleeding on probing (BOP), age, current diabetes, gestational diabetes, gestational hypertension, lack of Calcium, Folic acid, and Fe supplementation, mothers’ depression, polyhy dramnios, smoking severity and history of premature rupture of the membrane. The results also indicated an indirect relationship between an irregular tooth brushing and preterm birth. Conclusion: Attachment loss, calculus, bleeding on probing are directly related to premature labor and irregular tooth brushing is indirectly associated with early birth. Due to the direct relationship between periodontal diseases and preterm delivery, regular brushing, oral hygiene, oral examinations during pregnancy and follow-up treatment of periodontal disease during pregnancy are recommended. Keywords: Periodontal disease, Preterm labor, Cohort study, Path analysis, Pregnancy


2021 ◽  
Vol 28 (1) ◽  
pp. 36-41
Author(s):  
Didem Ekiz ◽  
Şeyda Erşahan ◽  
Ali Ekiz ◽  
Nurcan Altaş ◽  
Burak Özköse ◽  
...  

Objective In current obstetric literature, the influence of periodontal disease on adverse perinatal outcome is a matter of debate. In this prospective cohort study, we aimed to investigate whether there is an association between periodontal status and preterm birth (PTB) via previously unused methodology. Methods In this prospective cohort study, we examined the periodontal status of mothers within 24 hours following birth. In total, 226 puerperal women were examined and placed in two groups; a PTB group consisting of 71 patients, and a term birth (TB) group consisting of 155 patients. All risk factors known to be etiologic factors for PTB were excluded. The patients were classified into three main groups in both groups based on oral examination findings: gingivitis (G), periodontitis (P), and healthy (H). Results Both groups were identical in terms of demographic factors. Regarding possibly influencing factors including smoking, passive smoking and tooth brushing habits, both groups were also identical. The distribution of G, P and H among the groups were similar and the difference was not significant (p=1). p-values among the PTB and TB groups were 40.8% and 40.6%, respectively, and the difference was not significant. When collected data were reanalyzed by splitting the PTB group into early and late PTB, the results were similar and the difference was not significant. Conclusion The confusion over this conflicting association likely results from confounding factors, other factors that can cause PTB and lack of consensus over the diagnostic criteria for periodontal disease. Finally, our prospective cohort study, which strictly excluded possible confounding variables, has not confirmed any association between periodontitis and preterm birth.


2017 ◽  
Vol 216 (6) ◽  
pp. 600.e1-600.e9 ◽  
Author(s):  
David B. Nelson ◽  
Donald D. McIntire ◽  
Jeffrey McDonald ◽  
John Gard ◽  
Paula Turrichi ◽  
...  

PEDIATRICS ◽  
2016 ◽  
Vol 137 (4) ◽  
pp. e20152056-e20152056 ◽  
Author(s):  
P. Thunqvist ◽  
P. M. Gustafsson ◽  
E. S. Schultz ◽  
T. Bellander ◽  
E. Berggren-Brostro m ◽  
...  

2020 ◽  
Author(s):  
Evangelia Elenis ◽  
Anna-Karin Wikström ◽  
Marija Simic

Abstract Background: Preterm birth (occurring before 37 completed weeks of gestation) affects 15 million infants annually, 7.5% of which die due to related complications. The detection and early diagnosis are therefore paramount in order to prevent the development of prematurity and its consequences. So far, focus has been laid on the association between reduced intrauterine fetal growth during late gestation and prematurity. The aim of the current study was to investigate the association between accelerated fetal growth in early pregnancy and the risk of preterm birth. Methods: This prospective cohort study included 69 617 singleton pregnancies without congenital malformations and with available biometric measurements during the first and second trimester. Estimation of fetal growth was based on measurements of biparietal diameter (BPD) at first and second trimester scan. We investigated the association between accelerated fetal growth and preterm birth prior to 37 weeks of gestation. The outcome was further stratified into very preterm birth (before 32 weeks of gestation) or moderate preterm birth (between 32 and 37 weeks of gestation) and medically induced or spontaneous preterm birth and was further explored. Results: The odds of prematurity were increased among fetuses with accelerated BPD growth (> 90th centile) estimated between first and second ultrasound scan, even after adjustment for possible confounders (aOR 1.36; 95% CI 1.20-1.54). The findings remained significant what regards moderate preterm births but not earlier births. Regarding medically induced preterm birth, the odds were found to be elevated in the group of fetuses with accelerated growth in early pregnancy (aOR 1.34; 95% CI 1.11-1.63). On the contrary, fetuses with delayed fetal growth exhibited lower risk for both overall and spontaneous preterm birth.Conclusions: Fetuses with accelerated BPD growth in early pregnancy, detected by ultrasound examination during the second trimester, exhibited increased risk of being born preterm. The findings of the current study suggest that fetal growth in early pregnancy should be taken into account when assessing the likelihood for preterm birth.


2009 ◽  
Vol 38 (5) ◽  
pp. 1380-1389 ◽  
Author(s):  
Q. Zhang ◽  
C. V Ananth ◽  
Z. Li ◽  
J. C Smulian

2016 ◽  
Vol 48 (1) ◽  
pp. 38-42 ◽  
Author(s):  
J. Min ◽  
H. A. Watson ◽  
N. L. Hezelgrave ◽  
P. T. Seed ◽  
A. H. Shennan

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