scholarly journals Evaluation of Mean Platelet Volume and Other Complete Blood Count Parameters in Children with Atopic Asthma

2018 ◽  
Vol 6 (3) ◽  
pp. 181-185
Author(s):  
Dilek GIRAY ◽  
◽  
Mehmet OZDEMIR ◽  
Keyword(s):  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Atopic Asthma ◽  
Platelet Volume

scholarly journals The Role of Mean Platelet Volume on Distinction of Submucosal Myomas from Other Etiologies in Increased Endometrial Thickness

2016 ◽  
Vol 22 (1) ◽  
Author(s):  
Kerem Doğa Seçkin ◽  
Mehmet Fatih Karslı ◽  
Burak Yücel ◽  
Elif Akkaş Yılmaz ◽  
Murat Öz ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
White Blood Count ◽  
Control Group ◽  
Platelet Volume ◽  
Significant Difference

<p>OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding.<br />STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups.<br />RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p&gt;0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p&lt;0,05).<br />CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure.</p>

Complete Blood Count and Derived Indices: Evolution Pattern and Prognostic Value in Adult Burned Patients

2020 ◽  
Vol 41 (6) ◽  
pp. 1260-1266
Author(s):  
Martín Angulo ◽  
Laura Moreno ◽  
Ignacio Aramendi ◽  
Gimena dos Santos ◽  
Julio Cabrera ◽  
...  
Keyword(s):  
Mean Platelet Volume ◽  
Blood Count ◽  
Validation Cohort ◽  
Complete Blood Count ◽  
Platelet Volume ◽  
Discovery Cohort ◽  
Distribution Width ◽  
Lymphocyte Ratio ◽  
Inflammatory Status ◽  
Evolution Pattern

Abstract Certain parameters of complete blood count (CBC) such as red cell distribution width (RDW) and mean platelet volume, as well as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and RDW-to-platelet ratio (RPR) have been associated with inflammatory status and outcome in diverse medical conditions. The aim of this study was to describe the evolution pattern of these parameters in adult burned patients. Adult burned patients admitted to the National Burn Center in Uruguay between May 2017 and February 2018 (discovery cohort) and between March 2018 and August 2019 (validation cohort) were included. Patients’ characteristics and outcomes were recorded, as well as CBC parameters on days 1, 3, 5, and 7 after thermal injury. Eighty-eight patients were included in the discovery cohort. Total body surface area burned was 14 [7–23]% and mortality was 15%. Nonsurvivors presented higher RDW and mean platelet volume (P &lt; .01). NLR decreased after admission in all patients (P &lt; .01), but was higher in nonsurvivors (P &lt; .01). Deceased patients also presented higher RPR on days 3, 5, and 7 (P &lt; .001). On the contrary, PLR was reduced in nonsurvivors (P &lt; .05). There was a significant correlation between NLR on admission and burn extension and severity. Kaplan–Meier analysis revealed that NLR, PLR, and RPR could identify patients with increased mortality. These findings were confirmed in the validation cohort (n = 95). Basic CBC parameters and derived indices could be useful as biomarkers to determine prognosis in adults with thermal injuries.

scholarly journals Postpartum hemorrhage risk is driven by changes in blood composition through pregnancy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Matthew R. Robinson ◽  
Marion Patxot ◽  
Miloš Stojanov ◽  
Sabine Blum ◽  
David Baud
Keyword(s):  
Platelet Count ◽  
Blood Cell ◽  
Postpartum Hemorrhage ◽  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Platelet Volume ◽  
Distribution Width ◽  
Cell Counts ◽  
Blood Cell Counts

AbstractThe extent to which women differ in the course of blood cell counts throughout pregnancy, and the importance of these changes to pregnancy outcomes has not been well defined. Here, we develop a series of statistical analyses of repeated measures data to reveal the degree to which women differ in the course of pregnancy, predict the changes that occur, and determine the importance of these changes for post-partum hemorrhage (PPH) which is one of the leading causes of maternal mortality. We present a prospective cohort of 4082 births recorded at the University Hospital, Lausanne, Switzerland between 2009 and 2014 where full labour records could be obtained, along with complete blood count data taken at hospital admission. We find significant differences, at a $$p<0.001$$ p < 0.001 level, among women in how blood count values change through pregnancy for mean corpuscular hemoglobin, mean corpuscular volume, mean platelet volume, platelet count and red cell distribution width. We find evidence that almost all complete blood count values show trimester-specific associations with PPH. For example, high platelet count (OR 1.20, 95% CI 1.01–1.53), high mean platelet volume (OR 1.58, 95% CI 1.04–2.08), and high erythrocyte levels (OR 1.36, 95% CI 1.01–1.57) in trimester 1 increased PPH, but high values in trimester 3 decreased PPH risk (OR 0.85, 0.79, 0.67 respectively). We show that differences among women in the course of blood cell counts throughout pregnancy have an important role in shaping pregnancy outcome and tracking blood count value changes through pregnancy improves identification of women at increased risk of postpartum hemorrhage. This study provides greater understanding of the complex changes in blood count values that occur through pregnancy and provides indicators to guide the stratification of patients into risk groups.

Evaluation of Mean Platelet Volume Level as a Biomarker in Acute Appendicitis

2020 ◽  
Vol 22 (2) ◽  
pp. 83-88
Author(s):  
Ayesha Rahman ◽  
SM Syeed Ul Alam ◽  
Sanjana Sharmin Shashi ◽  
AZM Mostaque Hossain ◽  
Salma Sultana
Keyword(s):  
Acute Appendicitis ◽  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Clinical History ◽  
P Value ◽  
Platelet Volume ◽  
College Hospital ◽  
Neutrophil Percentage ◽  
Wbc Count

Background: Acute appendicitis is one of the important causes of emergency surgeries. Diagnosis of acute appendicitis remains to be challenging with up to 30% negative exploration rates. In addition to careful clinical history and physical examination, we still need easily applicable, cheap and effective biomarker. Complete blood count is the primary investigation for any inflammatory condition. Total WBC count and neutrophil percentage are widely used biomarkers to diagnose acute appendicitis. Mean platelet volume (MPV) is an emerging biomarker that has been considered to be affected by inflammatory burden. MPV value is also estimated during complete blood count. This study may help to reveal the change of MPV in acute appendicitis. Study design: This was a prospective observational type of study. Study setting and period: The study was carried out in the Surgery In-patient Department of Dhaka Medical College Hospital, Dhaka from 15-11-2013 till 15-04-2014. Materials: A total of 150 patients of both sex aged 15-65 years who got admitted in the surgery department for acute appendicitis were selected. Pediatric patients (aged less than 14years), patients with co morbid illness like ischemic heart disease, inflammatory bowel disease, general peritonitis and the patients having lack of necessary investigations were excluded from the study. Methods: The variables like total WBC count, neutrophil percentage, platelet count and mean platelet volume (MPV) of all 150 selected patients were noted after admission by doing complete blood count and compared with normal value. The appendix samples obtained after surgery were sent for histopathological confirmation and reports were collected. Results: A total of 150 patients with the mean age of 25.72 (ranging 15-65) years were studied. Among them 93(62%) were male and 57(38%) were female. Mean MPV value was 11.7 ± 0.183 fL (p value 0.02). 122 patients have increased MPV value (81.33%). Among them 113 were eventually diagnosed as acute appendicitis. Negative exploration rate was 14%.Negative exploration was less among MPV raised patients (7.38%). Whereas negative exploration was more among normal MPV patients (21.42%).Total WBC count and neutriphil percentage are important biomarkers to diagnose acute appendicitis which is accepted. However this study revealed MPV value is an important biomarker in acute appendicitis also which is statistically significant and can reduce negative exploration. Conclusion: In this study mean platelet volume increases in acute appendicitis. MPV can be used as a biomarker in diagnosis of acute appendicitis. Journal of Surgical Sciences (2018) Vol. 22 (2) : 83-88

scholarly journals Effects of Isotretinoin on the Platelet Counts and the Mean Platelet Volume in Patients with Acne Vulgaris

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Arzu Ataseven ◽  
Aynur Ugur Bilgin
Keyword(s):  
Bone Marrow ◽  
Retrospective Study ◽  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Acne Vulgaris ◽  
Blood Cell Count ◽  
Platelet Volume ◽  
Platelet Counts ◽  
The Mean

Aim. The aim of this study was to evaluate the platelet counts and the mean platelet volume in patients who received isotretinoin for the treatment of acne vulgaris.Method. A total of 110 patients were included in this retrospective study. Complete blood count parameters were recorded prior to and three-months following the treatment.Results. Both platelet counts and the mean platelet volume were significantly decreased following the treatment. No significant differences were noted on the levels of hemoglobin, hematocrit, and white blood cell count.Conclusion. Platelet counts and mean platelet volume significantly decreased following isotretinoin treatment. Since the decrease of platelet counts and the mean platelet volume was seen concomitantly, it is concluded that the effect of isotretinoin was through the suppression of bone marrow.

scholarly journals CTAD as a universal anticoagulant

2003 ◽  
Vol 25 (1) ◽  
pp. 17-20 ◽  
Author(s):  
M. Yokota ◽  
N. Tatsumi ◽  
I. Tsuda ◽  
T. Nishioka ◽  
T. Takubo
Keyword(s):  
Platelet Count ◽  
Whole Blood ◽  
Partial Thromboplastin Time ◽  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Activated Partial Thromboplastin Time ◽  
Medical Laboratory ◽  
Platelet Volume ◽  
Coagulation Tests

The feasibility of CTAD (a mixture of citrate, theophylline, adenosine and dipyridamole) as a new anticoagulant for medical laboratory use was studied prospectively. Whole blood anticoagulated with CTAD exhibited results very similar to those of blood anticoagulated with EDTA on complete blood count and automated white cell differential except for a slight decrease in platelet count and mean platelet volume. Chemistry test data for plasma obtained from CTAD whole blood were close to those obtained for matched sera. Among coagulation tests, prothrombin time, activated partial thromboplastin time and fibrinogen concentrations were close to those obtained with citrate plasma. Based on the results, CTAD was judged to be a good candidate as a new anticoagulant.

The effect of pre-eclampsia on complete blood count, platelet count and mean platelet volume

2006 ◽  
Vol 85 (5) ◽  
pp. 320-322 ◽  
Author(s):  
Temel Ceyhan ◽  
Cengiz Beyan ◽  
İskender Başer ◽  
Kürşat Kaptan ◽  
Sadettin Güngör ◽  
...  
Keyword(s):  
Platelet Count ◽  
Mean Platelet Volume ◽  
Blood Count ◽  
Complete Blood Count ◽  
Platelet Volume

scholarly journals Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Giuseppe Lippi ◽  
Gian Luca Salvagno ◽  
Elisa Danese ◽  
Cantor Tarperi ◽  
Gian Cesare Guidi ◽  
...  
Keyword(s):  
Blood Cell ◽  
Endurance Exercise ◽  
Red Blood Cell ◽  
Mean Platelet Volume ◽  
Complete Blood Count ◽  
Mean Corpuscular Hemoglobin ◽  
Reference Ranges ◽  
Platelet Volume ◽  
Distribution Width ◽  
Haemoglobin Content

Although physical exercise strongly influences several laboratory parameters, data about the hematological changes after medium distance running are scarce. We studied 31 middle-trained athletes (mean training regimen217±32 min/week) who performed a 21.1 km, half-marathon run. Blood samples were collected before the run, at the end, and 3 and 20 hours thereafter. The complete blood count was performed on Advia 2120 and included red blood cell (RBC), reticulocyte, and platelet counts; hemoglobin; mean corpuscular volume (MCV); mean corpuscular hemoglobin (MCH); reticulocyte haemoglobin content (Ret CHR); RBC distribution width (RDW), mean platelet volume (MPV). No significant variations were observed for MCH and Ret CHR. The RBC, reticulocyte, and hemoglobin values modestly decreased after the run. The MCV significantly increased at the end of running but returned to baseline 3 hours thereafter. The RDW constantly increased, reaching a peak 20 hours after the run. The platelet count and MPV both increased after the run and returned to baseline 3 hours thereafter. These results may have implications for definition of reference ranges and antidoping testing, and may also contribute to explaining the relationship between endurance exercise and mortality, since previous studies reported that RDW and MPV may be significantly associated with cardiovascular disease.

scholarly journals Study the relationship between nasal polyps, platelet count, mean platelet volume, neutrophil/lymphocyte ratio in patients attending otolaryngology OPD in a tertiary care teaching hospital, West Bengal

2017 ◽  
Vol 3 (2) ◽  
pp. 228
Author(s):  
Manuprita Sharma ◽  
Santosh Raman ◽  
Bidhan Ray ◽  
Rupali Verma Bagga ◽  
Ramesh Kumar Sahu ◽  
...  
Keyword(s):  
Platelet Count ◽  
Nasal Polyp ◽  
Mean Platelet Volume ◽  
Complete Blood Count ◽  
Tertiary Care ◽  
Control Group ◽  
Blood Cell Count ◽  
Platelet Volume ◽  
Distribution Width ◽  
The Relationship

<p class="abstract"><strong>Background:</strong> Nasal obstruction is a common cause of marked nasal septal deviation. It is related strongly with hypoxia. Hypoxic conditions increase mean platelet volume levels. Many studies in literature point out that inflammation related to nasal polyp is mostly dependent on eosinophils and their inflammatory products. Beside eosinophils, platelets may have a role in nasal polyp development. Platelets are involved in hemostasis, tissue repairing and inflammation. Recently, mean platelet volume (MPV) was recognized as a simple inflammatory marker in the inflammatory disease<span lang="EN-IN">. </span>This study investigated the relationship of nasal polyps with MPV (mean platelet volume), platelet count and NLR (neutrophil to lymphocyte ratio).</p><p class="abstract"><strong>Methods:</strong> The cross-sectional observational study we investigated CBC (complete blood count) parameters of the patients that consulted ENT clinic in a tertiary care teaching hospital, Haldia because of nasal polyp. <span>About 76 patients and 42 controls were included in this study. In all groups, WBC (white blood cell count), RBC (red blood cell count), RDW (red cell distribution width), platelet count, MPV, PDW (platelet distribution width) and NLR parameters from CBC (complete blood count) were compared between patients and controls</span><span lang="EN-IN">.  </span></p><p class="abstract"><strong>Results:</strong> Mean WBC values were 6.89±1.33×103/μL in patients with NPs, vs. 7.11±2.32×103/μL in the control group. Mean haemoglobin (Hb) values were 13.19±1.34 g/dL in patients with NPs, vs. 14.1±1.67 g/dl in the control group. Mean MPV values were 9.11 ± 1.08 fL in patients with NPs, vs. 8.32±0.53 fL in the control group. Mean PLT values were 232.38 ± 39.97×103/μL in patients with NPs, vs. 271.44±45.14×103 in the control group. MPV was higher in nasal polyp patients, whereas platelet count was higher in controls. The difference was significant for the mean absolute neutrophil, platelet count, and lymphocyte counts, NLR, PDW and MPV values between the study group and the control group<span lang="EN-IN">. </span></p><p class="abstract"><strong>Conclusions:</strong> Platelet count and NLR were significantly lower in patients than the controls, whereas MPV was significantly higher in nasal polyp patients<span lang="EN-IN">.</span></p>

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