scholarly journals Effects of low dose radiation on survival of lung cancer patients

2017 ◽  
Author(s):  
Huriye Senay KIZILTAN ◽  
Alpaslan MAYADAGLI ◽  
Ali Hikmet ERIS ◽  
Ozgur KABLAN ◽  
Sezgi Turan EROGUZ ◽  
...  
2018 ◽  
Vol 6 (2) ◽  
pp. 108-111
Author(s):  
Huriye Senay KIZILTAN ◽  
◽  
Alpaslan MAYADAGLI ◽  
Ali Hikmet ERIS ◽  
Ozgur KABLAN ◽  
...  

Author(s):  
Hamid Ghaznavi ◽  
Farideh Elahimanesh ◽  
Jamil Abdolmohammadi ◽  
Meysam Mirzaie ◽  
Sadegh Ghaderi

Abstract Background: The Coronavirus disease 2019 (COVID-19) is spreading rapidly throughout the world. Lung is the primary organ which the COVID-19 virus affects and leads to pneumonia, an acute respiratory distress syndrome. COVID-19 infects the lower respiratory system, and the lung’s response to this infection is recruiting macrophages and monocytes leading to inflammation, this response causes widespread damage to the lung’s airways. Aim: The purpose of this study is to review studies of using low-dose radiation as a treatment for the inflammation of the tissue and pneumonia resulting from COVID-19. These studies were compared with the risk of developing lung cancer during performed dose for the treatment of COVID-19 in radiation therapy. Materials and methods: Our study focused on in vitro, in vivo and clinical reports of using low-dose radiation for the treatment of inflammation, pneumonia and COVID-19. The risk of lung cancer resulting from suggested dose in these studies was also evaluated. Conclusion: From the review of articles, we have found that low-dose radiation can lead to improvement in inflammation in different line cells and animals; in addition, it has been effective in treating inflammation and pneumonia caused by COVID-19 in human up to 80%. Since suggested doses do not remarkably increase the lung cancer risk, low-dose radiation can be an adjuvant treatment for COVID-19 patients.


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1610-1610
Author(s):  
Ping Yang ◽  
Kathleen J. Yost ◽  
Matthew M. Clark ◽  
Mariza de Andrade ◽  
Katherine M. Piderman ◽  
...  

1610 Background: Low dose computed tomography (LDCT) scans have reduced lung cancer deaths by 20.3% in high risk populations, although there is an unknown balance between the benefits and harms of LDCT scans as a screening tool. Our purpose was to compare health-related QOL issues among lung cancer patients who were initially detected by LDCT scans; 4 comparison groups included: lung cancer diagnosed by a screening chest X-ray, as an incidental finding from procedures taken for other medical reasons, or based on symptoms indicative for lung cancer and routinely diagnosed, and individuals who were LDCT screened but found no lung cancer (controls who participated in Mayo’s lung cancer CT screening trial). Methods: A total of 1,658 lung cancer patients (cared at Mayo Clinic) in the 4 groups (37, 151, 389, and 1081 respectively) and 488 controls were compared on following patient-reported outcomes (collected via validated tools): overall QOL, four symptoms (cough, pain, dyspnea, fatigue), mental/ physical/ emotional/ social/ spiritual QOL, and other concerns (e.g., family/ friends/ financial/ legal). A clinically significant deficit was defined as at least 10-points in difference (or <50 points) on a 0-100 scale. The rates of deficits were compared via Fisher’s exact tests and average QOL values via Kruskal-Wallis tests. Results: Overall QOL and individual symptoms were significantly worse (p<0.05) in all lung cancer groups than in controls, except for pain. LDCT-screened patients reported the greatest deficit among the 4 lung cancer groups in physical (41%), emotional (24%), social (38%), and spiritual QOL (24%); whereas chest X-ray detected patients had the least deficit in overall QOL (22%) and pain (32%). All 4 lung cancer groups experienced much worse fatigue (52-64%) than the controls (32%). Conclusions: Our preliminary results suggest that LDCT-screening detected lung cancer patients reported a different QOL profile from other lung cancer patients and non-lung cancer controls. The clinical course, smoking behavior, and QOL related health issues associated with LDCT screening for lung cancer warrant thorough investigation.


2010 ◽  
Vol 94 ◽  
pp. S41-S42
Author(s):  
H. Keller ◽  
D. Vines ◽  
M. Lakshman ◽  
M. Dunne ◽  
P. Lindsay ◽  
...  

2021 ◽  
Author(s):  
Edmund M. Qiao ◽  
Rohith S. Voora ◽  
Vinit Nalawade ◽  
Nikhil V. Kotha ◽  
Alexander S. Qian ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document